8V6R
Crystal structure of EcThsA in complex with ADPR
Summary for 8V6R
Entry DOI | 10.2210/pdb8v6r/pdb |
Descriptor | Thoeris protein ThsA Macro domain-containing protein, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE (3 entities in total) |
Functional Keywords | antiphage immunity, nucleotide signalling, immune system |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 56733.63 |
Authors | Shi, Y.,Masic, V.,Mosaiab, T.,Goulart, C.C.,Hartley-Tassell, L.,Sorbello, M.,Vasquez, E.,Mishra, B.P.,Holt, S.,Gu, W.,Kobe, B.,Ve, T. (deposition date: 2023-12-02, release date: 2024-06-12, Last modification date: 2024-07-10) |
Primary citation | Shi, Y.,Masic, V.,Mosaiab, T.,Rajaratman, P.,Hartley-Tassell, L.,Sorbello, M.,Goulart, C.C.,Vasquez, E.,Mishra, B.P.,Holt, S.,Gu, W.,Kobe, B.,Ve, T. Structural characterization of macro domain-containing Thoeris antiphage defense systems. Sci Adv, 10:eadn3310-eadn3310, 2024 Cited by PubMed: 38924412DOI: 10.1126/sciadv.adn3310 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.14 Å) |
Structure validation
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