8V6S

Crystal structure of PcThsA in complex with Imidazole Adenine Dinucleotide

Summary for 8V6S

• Entry DOI: 10.2210/pdb8v6s/pdb
• Descriptor: Thoeris protein ThsA Macro domain-containing protein, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-imidazol-1-yl-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate (3 entities in total)
• Functional Keywords: antiphage immunity, nucleotide signalling, immune system
• Biological source: Pseudomonas corrugata
• Total number of polymer chains: 2
• Total formula weight: 56395.72

Authors

Shi, Y.,Masic, V.,Mosaiab, T.,Goulart, C.C.,Hartley-Tassell, L.,Sorbello, M.,Vasquez, E.,Mishra, B.P.,Holt, S.,Gu, W.,Kobe, B.,Ve, T. (deposition date: 2023-12-02, release date: 2024-06-12, Last modification date: 2024-07-10)

• Primary citation: Shi, Y.,Masic, V.,Mosaiab, T.,Rajaratman, P.,Hartley-Tassell, L.,Sorbello, M.,Goulart, C.C.,Vasquez, E.,Mishra, B.P.,Holt, S.,Gu, W.,Kobe, B.,Ve, T.; Structural characterization of macro domain-containing Thoeris antiphage defense systems.; Sci Adv, 10:eadn3310-eadn3310, 2024; PubMed: 38924412; DOI: 10.1126/sciadv.adn3310

Experimental method

X-RAY DIFFRACTION (1.6 Å)