7TO9
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7TO7
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7T2Q
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![BU of 7t2q by Molmil](/molmil-images/mine/7t2q) | PEGylated Calmodulin-1 (K148U) | Descriptor: | CALCIUM ION, Calmodulin-1, MAGNESIUM ION, ... | Authors: | Mackay, J.P, Payne, R.J, Patel, K, Dowman, L.J. | Deposit date: | 2021-12-06 | Release date: | 2022-10-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Site-selective photocatalytic functionalization of peptides and proteins at selenocysteine. Nat Commun, 13, 2022
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2HI3
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![BU of 2hi3 by Molmil](/molmil-images/mine/2hi3) | Solution structure of the homeodomain-only protein HOP | Descriptor: | Homeodomain-only protein | Authors: | Mackay, J.P, Kook, H, Epstein, J.A, Simpson, R.J, Yung, W.W. | Deposit date: | 2006-06-28 | Release date: | 2007-01-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Analysis of the structure and function of the transcriptional coregulator HOP Biochemistry, 45, 2006
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2MPL
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2RPN
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![BU of 2rpn by Molmil](/molmil-images/mine/2rpn) | A crucial role for high intrinsic specificity in the function of yeast SH3 domains | Descriptor: | Actin-binding protein, Actin-regulating kinase 1 | Authors: | Stollar, E.J, Garcia, B, Chong, A, Forman-Kay, J, Davidson, A. | Deposit date: | 2008-06-12 | Release date: | 2009-06-16 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p J.Biol.Chem., 284, 2009
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6UK1
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![BU of 6uk1 by Molmil](/molmil-images/mine/6uk1) | Crystal structure of nucleotide-binding domain 2 (NBD2) of the human Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | Authors: | Wang, C, Vorobiev, S.M, Vernon, R.M, Khazanov, N, Senderowitz, H, Forman-Kay, J.D, Hunt, J.F. | Deposit date: | 2019-10-03 | Release date: | 2020-10-07 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.693 Å) | Cite: | A thermodynamically stabilized form of the second nucleotide binding domain from human CFTR shows a catalytically inactive conformation To Be Published
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1DDM
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![BU of 1ddm by Molmil](/molmil-images/mine/1ddm) | SOLUTION STRUCTURE OF THE NUMB PTB DOMAIN COMPLEXED TO A NAK PEPTIDE | Descriptor: | NUMB ASSOCIATE KINASE, NUMB PROTEIN | Authors: | Zwahlen, C, Li, S.C, Kay, L.E, Pawson, T, Forman-Kay, J.D. | Deposit date: | 1999-11-11 | Release date: | 2000-04-10 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Multiple modes of peptide recognition by the PTB domain of the cell fate determinant Numb. EMBO J., 19, 2000
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1KA7
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![BU of 1ka7 by Molmil](/molmil-images/mine/1ka7) | SAP/SH2D1A bound to peptide n-Y-c | Descriptor: | SH2 DOMAIN PROTEIN 1A, peptide n-Y-c | Authors: | Hwang, P.M, Li, C, Morra, M, Lillywhite, J, Gertler, F, Terhorst, C, Kay, L.E, Pawson, T, Forman-Kay, J, Li, S.-C. | Deposit date: | 2001-10-31 | Release date: | 2001-11-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome. EMBO J., 21, 2002
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1KA6
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![BU of 1ka6 by Molmil](/molmil-images/mine/1ka6) | SAP/SH2D1A bound to peptide n-pY | Descriptor: | SH2 DOMAIN PROTEIN 1A, peptide n-pY | Authors: | Hwang, P.M, Li, C, Morra, M, Lillywhite, J, Gertler, F, Terhorst, C, Kay, L.E, Pawson, T, Forman-Kay, J, Li, S.-C. | Deposit date: | 2001-10-31 | Release date: | 2001-11-07 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome. EMBO J., 21, 2002
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3TRX
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2MX4
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![BU of 2mx4 by Molmil](/molmil-images/mine/2mx4) | NMR structure of Phosphorylated 4E-BP2 | Descriptor: | Eukaryotic translation initiation factor 4E-binding protein 2 | Authors: | Bah, A, Forman-Kay, J, Vernon, R, Siddiqui, Z, Krzeminski, M, Muhandiram, R, Zhao, C, Sonenberg, N, Kay, L. | Deposit date: | 2014-12-10 | Release date: | 2015-01-07 | Last modified: | 2015-03-18 | Method: | SOLUTION NMR | Cite: | Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch. Nature, 519, 2015
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2NMB
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![BU of 2nmb by Molmil](/molmil-images/mine/2nmb) | DNUMB PTB DOMAIN COMPLEXED WITH A PHOSPHOTYROSINE PEPTIDE, NMR, ENSEMBLE OF STRUCTURES. | Descriptor: | PROTEIN (GPPY PEPTIDE), PROTEIN (NUMB PROTEIN) | Authors: | Li, S.-C, Zwahlen, C, Vincent, S.J.F, McGlade, C.J, Pawson, T, Forman-Kay, J.D. | Deposit date: | 1998-10-29 | Release date: | 1998-11-04 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificity. Nat.Struct.Biol., 5, 1998
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4TRX
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1JU5
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![BU of 1ju5 by Molmil](/molmil-images/mine/1ju5) | Ternary complex of an Crk SH2 domain, Crk-derived phophopeptide, and Abl SH3 domain by NMR spectroscopy | Descriptor: | Abl, Crk | Authors: | Donaldson, L.W, Pawson, T, Kay, L.E, Forman-Kay, J.D. | Deposit date: | 2001-08-23 | Release date: | 2002-11-06 | Last modified: | 2021-11-10 | Method: | SOLUTION NMR | Cite: | Structure of a regulatory complex involving the Abl SH3 domain, the Crk
SH2 domain, and a Crk-derived phosphopeptide Proc.Natl.Acad.Sci.USA, 99, 2002
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2PLE
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![BU of 2ple by Molmil](/molmil-images/mine/2ple) | NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE | Descriptor: | PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF | Authors: | Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D. | Deposit date: | 1994-08-19 | Release date: | 1995-01-26 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide. Cell(Cambridge,Mass.), 77, 1994
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2PLD
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![BU of 2pld by Molmil](/molmil-images/mine/2pld) | NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE | Descriptor: | PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF | Authors: | Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D. | Deposit date: | 1994-08-19 | Release date: | 1995-01-26 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide. Cell(Cambridge,Mass.), 77, 1994
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2KIS
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![BU of 2kis by Molmil](/molmil-images/mine/2kis) | Solution structure of CA150 FF1 domain and FF1-FF2 interdomain linker | Descriptor: | Transcription elongation regulator 1 | Authors: | Murphy, J.M, Hansen, D, Wiesner, S, Muhandiram, D, Borg, M, Smith, M.J, Sicheri, F, Kay, L.E, Forman-Kay, J.D, Pawson, T. | Deposit date: | 2009-05-08 | Release date: | 2009-09-08 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Structural studies of FF domains of the transcription factor CA150 provide insights into the organization of FF domain tandem arrays. J.Mol.Biol., 393, 2009
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1EZP
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![BU of 1ezp by Molmil](/molmil-images/mine/1ezp) | GLOBAL FOLD OF MALTODEXTRIN BINDING PROTEIN COMPLEXED WITH BETA-CYCLODEXTRIN USING PEPTIDE ORIENTATIONS FROM DIPOLAR COUPLINGS | Descriptor: | MALTODEXTRIN BINDING PERIPLASMIC PROTEIN | Authors: | Mueller, G.A, Choy, W.Y, Yang, D, Forman-Kay, J.D, Venters, R.A, Kay, L.E. | Deposit date: | 2000-05-11 | Release date: | 2001-05-08 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Global folds of proteins with low densities of NOEs using residual dipolar couplings: application to the 370-residue maltodextrin-binding protein. J.Mol.Biol., 300, 2000
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1MM5
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![BU of 1mm5 by Molmil](/molmil-images/mine/1mm5) | Solution NMR structure of the outer membrane enzyme PagP in OG micelles | Descriptor: | CrcA protein | Authors: | Hwang, P.M, Choy, W.-Y, Lo, E.I, Chen, L, Forman-Kay, J.D, Raetz, C.R.H, Prive, G.G, Bishop, R.E, Kay, L.E. | Deposit date: | 2002-09-03 | Release date: | 2002-09-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Structure and Dynamics of the Outer Membrane Enzyme PagP by NMR Proc.Natl.Acad.Sci.USA, 99, 2002
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1MM4
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![BU of 1mm4 by Molmil](/molmil-images/mine/1mm4) | Solution NMR structure of the outer membrane enzyme PagP in DPC micelles | Descriptor: | CrcA protein | Authors: | Hwang, P.M, Choy, W.-Y, Lo, E.I, Chen, L, Forman-Kay, J.D, Raetz, C.R.H, Prive, G.G, Bishop, R.E, Kay, L.E. | Deposit date: | 2002-09-03 | Release date: | 2002-09-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Structure and Dynamics of the Outer Membrane Enzyme PagP by NMR Proc.Natl.Acad.Sci.USA, 99, 2002
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1EZO
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![BU of 1ezo by Molmil](/molmil-images/mine/1ezo) | GLOBAL FOLD OF MALTODEXTRIN BINDING PROTEIN COMPLEXED WITH BETA-CYCLODEXTRIN | Descriptor: | MALTOSE-BINDING PERIPLASMIC PROTEIN | Authors: | Mueller, G.A, Choy, W.Y, Yang, D, Forman-Kay, J.D, Venters, R.A, Kay, L.E. | Deposit date: | 2000-05-11 | Release date: | 2001-05-03 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Global folds of proteins with low densities of NOEs using residual dipolar couplings: application to the 370-residue maltodextrin-binding protein. J.Mol.Biol., 300, 2000
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3V7D
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![BU of 3v7d by Molmil](/molmil-images/mine/3v7d) | Crystal Structure of ScSkp1-ScCdc4-pSic1 peptide complex | Descriptor: | Cell division control protein 4, Protein SIC1, Suppressor of kinetochore protein 1 | Authors: | Tang, X, Orlicky, S, Mittag, T, Csizmok, V, Pawson, T, Forman-Kay, J, Sicheri, F, Tyers, M. | Deposit date: | 2011-12-20 | Release date: | 2012-05-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.306 Å) | Cite: | Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 109, 2012
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2DJY
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![BU of 2djy by Molmil](/molmil-images/mine/2djy) | Solution structure of Smurf2 WW3 domain-Smad7 PY peptide complex | Descriptor: | Mothers against decapentaplegic homolog 7, Smad ubiquitination regulatory factor 2 | Authors: | Chong, P.A, Lin, H, Wrana, J.L, Forman-Kay, J.D. | Deposit date: | 2006-04-06 | Release date: | 2006-05-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | An Expanded WW Domain Recognition Motif Revealed by the Interaction between Smad7 and the E3 Ubiquitin Ligase Smurf2. J.Biol.Chem., 281, 2006
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2AZV
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![BU of 2azv by Molmil](/molmil-images/mine/2azv) | Solution structure of the T22G mutant of N-terminal SH3 domain of DRK (calculated without NOEs) | Descriptor: | SH2-SH3 adapter protein drk | Authors: | Bezsonova, I, Singer, A.U, Choy, W.-Y, Tollinger, M, Forman-Kay, J.D. | Deposit date: | 2005-09-12 | Release date: | 2005-12-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural Comparison of the Unstable drkN SH3 Domain and a Stable Mutant Biochemistry, 44, 2005
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