7TO7

BRD3-BD1 in complex with RaPID linear peptide 1xAcK.4XE (monoAcK.4xE)

Summary for 7TO7

Entry DOI	10.2210/pdb7to7/pdb
Descriptor	Bromodomain-containing protein 3, 1xAcK.4xE (monoAcK.4xE), GLYCEROL, ... (4 entities in total)
Functional Keywords	bet, bromodomain, rapid, brd3, acetylated, transcription
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	64175.78
Authors	Mackay, J.P.,Low, J.K.K.,Patel, K. (deposition date: 2022-01-23, release date: 2023-01-25, Last modification date: 2024-02-07)
Primary citation	Low, J.K.K.,Patel, K.,Jones, N.,Solomon, P.,Norman, A.,Maxwell, J.W.C.,Pachl, P.,Matthews, J.M.,Payne, R.J.,Passioura, T.,Suga, H.,Walport, L.J.,Mackay, J.P. mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome. J.Biol.Chem., 299:105482-105482, 2023 Cited by PubMed: 37992806 DOI: 10.1016/j.jbc.2023.105482 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.93 Å)

Structure validation