1JU5

Ternary complex of an Crk SH2 domain, Crk-derived phophopeptide, and Abl SH3 domain by NMR spectroscopy

Summary for 1JU5

Related1AWO 1BBZ 2ABL 1AYA 2PLD 1SPS
DescriptorCrk, Abl (3 entities in total)
Functional Keywordscrk, sh2, abl, sh3, adaptor protein, phosphopeptide, protein binding-transferase complex, protein binding/transferase
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm (By similarity) P46108 Q64010
Cytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor P00519
Total number of polymer chains3
Total molecular weight20375.51
Authors
Donaldson, L.W.,Pawson, T.,Kay, L.E.,Forman-Kay, J.D. (deposition date: 2001-08-23, release date: 2002-11-06, Last modification date: 2011-07-13)
Primary citation
Donaldson, L.W.,Gish, G.,Pawson, T.,Kay, L.E.,Forman-Kay, J.D.
Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide
Proc.Natl.Acad.Sci.USA, 99:14053-14058, 2002
PubMed: 12384576 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.212518799
MImport into Mendeley
Experimental method
SOLUTION NMR
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers312.9%21.4%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

Molmil generated image of 1ju5
no rotation
Molmil generated image of 1ju5
rotated about x axis by 90°
Molmil generated image of 1ju5
rotated about y axis by 90°