1SPS
BINDING OF A HIGH AFFINITY PHOSPHOTYROSYL PEPTIDE TO THE SRC SH2 DOMAIN: CRYSTAL STRUCTURES OF THE COMPLEXED AND PEPTIDE-FREE FORMS
Summary for 1SPS
Entry DOI | 10.2210/pdb1sps/pdb |
Descriptor | SRC SH2 DOMAIN, PEPTIDE YEEI (3 entities in total) |
Functional Keywords | transferase(phosphotransferase) |
Biological source | Rous sarcoma virus More |
Cellular location | Host membrane; Single-pass membrane protein (Potential): P03079 |
Total number of polymer chains | 6 |
Total formula weight | 40331.99 |
Authors | Waksman, G.,Kuriyan, J. (deposition date: 1993-03-05, release date: 1994-05-31, Last modification date: 2024-06-05) |
Primary citation | Waksman, G.,Shoelson, S.E.,Pant, N.,Cowburn, D.,Kuriyan, J. Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms. Cell(Cambridge,Mass.), 72:779-790, 1993 Cited by PubMed: 7680960DOI: 10.1016/0092-8674(93)90405-F PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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