2ABL

SH3-SH2 DOMAIN FRAGMENT OF HUMAN BCR-ABL TYROSINE KINASE

Summary for 2ABL

DescriptorABL TYROSINE KINASE (2 entities in total)
Functional Keywordstransferase, tyrosine kinase, sh3, sh2, oncoprotein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor P00519
Total number of polymer chains1
Total molecular weight18122.95
Authors
Nam, H.-J.,Frederick, C.A. (deposition date: 1996-11-17, release date: 1997-09-04, Last modification date: 2011-07-13)
Primary citation
Nam, H.J.,Haser, W.G.,Roberts, T.M.,Frederick, C.A.
Intramolecular interactions of the regulatory domains of the Bcr-Abl kinase reveal a novel control mechanism.
Structure, 4:1105-1114, 1996
PubMed: 8805596 (PDB entries with the same primary citation)
DOI: 10.1016/S0969-2126(96)00116-5
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers2012.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution