1AYA

CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE

Summary for 1AYA

DescriptorPROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN), PEPTIDE PDGFR-1009 (3 entities in total)
Functional Keywordshydrolase(sh2 domain)
Biological sourceMus musculus (house mouse)
Cellular locationCytoplasm P35235
Membrane; Single-pass type I membrane protein P05622
Total number of polymer chains4
Total molecular weight25658.57
Authors
Lee, C.-H.,Kuriyan, J. (deposition date: 1994-05-15, release date: 1994-08-31, Last modification date: 2011-07-13)
Primary citation
Lee, C.H.,Kominos, D.,Jacques, S.,Margolis, B.,Schlessinger, J.,Shoelson, S.E.,Kuriyan, J.
Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
Structure, 2:423-438, 1994
PubMed: 7521735 (PDB entries with the same primary citation)
DOI: 10.1016/S0969-2126(00)00044-7
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.05 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers71.0%7.4%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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More Biological unit images

Molmil generated image of 1aya
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Molmil generated image of 1aya
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (1aya.pdb1.gz [21.55 KB])
Coordinate files for Biological unit (1aya.pdb2.gz [20.07 KB])