6IU9
| Crystal structure of cytoplasmic metal binding domain with iron ions | Descriptor: | FE (II) ION, VIT1, ZINC ION | Authors: | Kato, T, Nishizawa, T, Yamashita, K, Kumazaki, K, Ishitani, R, Nureki, O. | Deposit date: | 2018-11-27 | Release date: | 2019-02-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of plant vacuolar iron transporter VIT1. Nat Plants, 5, 2019
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6IU5
| Crystal structure of cytoplasmic metal binding domain with zinc ions | Descriptor: | CHLORIDE ION, VIT1, ZINC ION | Authors: | Kato, T, Nishizawa, T, Yamashita, K, Kumazaki, K, Ishitani, R, Nureki, O. | Deposit date: | 2018-11-27 | Release date: | 2019-02-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal structure of plant vacuolar iron transporter VIT1. Nat Plants, 5, 2019
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6IU4
| Crystal structure of iron transporter VIT1 with cobalt ion | Descriptor: | COBALT (II) ION, VIT1, ZINC ION | Authors: | Kato, T, Nishizawa, T, Yamashita, K, Taniguchi, R, Kumazaki, K, Ishitani, R, Nureki, O. | Deposit date: | 2018-11-27 | Release date: | 2019-02-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Crystal structure of plant vacuolar iron transporter VIT1. Nat Plants, 5, 2019
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6IU8
| Crystal structure of cytoplasmic metal binding domain with cobalt ions | Descriptor: | COBALT (II) ION, VIT1, ZINC ION | Authors: | Kato, T, Nishizawa, T, Yamashita, K, Kumazaki, K, Ishitani, R, Nureki, O. | Deposit date: | 2018-11-27 | Release date: | 2019-02-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of plant vacuolar iron transporter VIT1. Nat Plants, 5, 2019
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6IU6
| Crystal structure of cytoplasmic metal binding domain with nickel ions | Descriptor: | NICKEL (II) ION, VIT1, ZINC ION | Authors: | Kato, T, Nishizawa, T, Yamashita, K, Kumazaki, K, Ishitani, R, Nureki, O. | Deposit date: | 2018-11-27 | Release date: | 2019-02-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of plant vacuolar iron transporter VIT1. Nat Plants, 5, 2019
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6IU3
| Crystal structure of iron transporter VIT1 with zinc ions | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, VIT1, ZINC ION | Authors: | Kato, T, Nishizawa, T, Yamashita, K, Taniguchi, R, Kumazaki, K, Ishitani, R, Nureki, O. | Deposit date: | 2018-11-27 | Release date: | 2019-02-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of plant vacuolar iron transporter VIT1. Nat Plants, 5, 2019
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7VR8
| Inward-facing structure of human EAAT2 in the substrate-free state | Descriptor: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, ... | Authors: | Kato, T, Kusakizako, T, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2021-10-22 | Release date: | 2022-08-10 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Structural insights into inhibitory mechanism of human excitatory amino acid transporter EAAT2. Nat Commun, 13, 2022
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7VR7
| Inward-facing structure of human EAAT2 in the WAY213613-bound state | Descriptor: | (2S)-2-azanyl-4-[[4-[2-bromanyl-4,5-bis(fluoranyl)phenoxy]phenyl]amino]-4-oxidanylidene-butanoic acid, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | Authors: | Kato, T, Kusakizako, T, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2021-10-22 | Release date: | 2022-08-10 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Structural insights into inhibitory mechanism of human excitatory amino acid transporter EAAT2. Nat Commun, 13, 2022
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6K9Q
| Structure of the native supercoiled hook as a universal joint | Descriptor: | Flagellar hook protein FlgE | Authors: | Kato, T, Miyata, T, Makino, F, Horvath, P, Namba, K. | Deposit date: | 2019-06-17 | Release date: | 2020-02-12 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of the native supercoiled flagellar hook as a universal joint. Nat Commun, 10, 2019
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7WLS
| Crystal structure of the multidrug efflux transporter BpeB from Burkholderia pseudomallei | Descriptor: | Efflux pump membrane transporter, TETRAETHYLENE GLYCOL, UNDECYL-MALTOSIDE | Authors: | Kato, T, Hung, L.-W, Yamashita, E, Okada, U, Terwilliger, T.C, Murakami, S. | Deposit date: | 2022-01-13 | Release date: | 2023-07-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Crystal structures of multidrug efflux transporters from Burkholderia pseudomallei suggest details of transport mechanism. Proc.Natl.Acad.Sci.USA, 120, 2023
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7WLV
| Crystal Structure of the Multidrug effulx transporter BpeF from Burkholderia pseudomallei. | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Efflux pump membrane transporter | Authors: | Kato, T, Hung, L.-W, Yamashita, E, Okada, U, Terwilliger, T.C, Murakami, S. | Deposit date: | 2022-01-13 | Release date: | 2023-07-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structures of multidrug efflux transporters from Burkholderia pseudomallei suggest details of transport mechanism. Proc.Natl.Acad.Sci.USA, 120, 2023
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6O97
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with propylamycin and bound to mRNA and A-, P-, and E-site tRNAs at 2.75A resolution | Descriptor: | (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxyc yclohexyl 2-amino-2,4-dideoxy-4-propyl-alpha-D-glucopyranoside, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Matsushita, T, Sati, G.C, Kondasinghe, N, Pirrone, M.G, Kato, T, Waduge, P, Kumar, H.S, Sanchon, A.C, Dobosz-Bartoszek, M, Shcherbakov, D, Juhas, M, Hobbie, S.N, Schrepfer, T, Chow, C.S, Polikanov, Y.S, Schacht, J, Vasella, A, Bottger, E.C, Crich, D. | Deposit date: | 2019-03-13 | Release date: | 2019-04-17 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Design, Multigram Synthesis, and in Vitro and in Vivo Evaluation of Propylamycin: A Semisynthetic 4,5-Deoxystreptamine Class Aminoglycoside for the Treatment of Drug-Resistant Enterobacteriaceae and Other Gram-Negative Pathogens. J. Am. Chem. Soc., 141, 2019
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8Z4G
| Structure of the S-ring region of the Vibrio flagellar MS-ring protein FliF with 35-fold symmetry applied | Descriptor: | Flagellar M-ring protein,Flagellar motor switch protein FliG | Authors: | Takekawa, N, Nishikino, T, Kishikawa, J, Hirose, M, Kato, T, Imada, K, Homma, M. | Deposit date: | 2024-04-17 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Structural analysis of S-ring composed of FliFG fusion proteins in marine Vibrio polar flagellar motors To Be Published
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8Z4D
| Structure of the S-ring region of the Vibrio flagellar MS-ring protein FliF with 34-fold symmetry applied | Descriptor: | Flagellar M-ring protein,Flagellar motor switch protein FliG | Authors: | Takekawa, N, Nishikino, T, Kishikawa, J, Hirose, M, Kato, T, Imada, K, Homma, M. | Deposit date: | 2024-04-17 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Structural analysis of S-ring composed of FliFG fusion proteins in marine Vibrio polar flagellar motors To Be Published
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8W8M
| Cryo-EM structure of helical filament of MyD88 TIR | Descriptor: | Myeloid differentiation primary response protein MyD88 | Authors: | Kasai, K, Imamura, K, Narita, A, Makino, F, Miyata, T, Kato, T, Namba, K, Onishi, H, Tochio, H. | Deposit date: | 2023-09-04 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Signaling adopter protein in a self-assembled form To Be Published
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1RCH
| SOLUTION NMR STRUCTURE OF RIBONUCLEASE HI FROM ESCHERICHIA COLI, 8 STRUCTURES | Descriptor: | RIBONUCLEASE HI | Authors: | Yamazaki, T, Fujiwara, M, Kato, T, Yamasaki, K, Nagayama, K. | Deposit date: | 1995-06-23 | Release date: | 1997-02-12 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Structure of Ribonuclease Hi from Escherichia Coli Biol.Pharm.Bull., 23, 2000
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3J0R
| Model of a type III secretion system needle based on a 7 Angstrom resolution cryoEM map | Descriptor: | Protein mxiH | Authors: | Fujii, T, Cheung, M, Blanco, A, Kato, T, Blocker, A.J, Namba, K. | Deposit date: | 2011-11-03 | Release date: | 2012-02-29 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Structure of a type III secretion needle at 7-A resolution provides insights into its assembly and signaling mechanisms. Proc.Natl.Acad.Sci.USA, 109, 2012
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1V7M
| Human Thrombopoietin Functional Domain Complexed To Neutralizing Antibody TN1 Fab | Descriptor: | Monoclonal TN1 Fab Heavy Chain, Monoclonal TN1 Fab Light Chain, Thrombopoietin | Authors: | Feese, M.D, Tamada, T, Kato, Y, Maeda, Y, Hirose, M, Matsukura, Y, Shigematsu, H, Kato, T, Miyazaki, H, Kuroki, R. | Deposit date: | 2003-12-18 | Release date: | 2004-03-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment Proc.Natl.Acad.Sci.USA, 101, 2004
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8H4O
| Crystal Structure of nucleotide-free Irgb6_T95D mutant | Descriptor: | T-cell-specific guanine nucleotide triphosphate-binding protein 2 | Authors: | Saijo-Hamano, Y, Okuma, H, Sakai, N, Kato, T, Imasaki, T, Nitta, R. | Deposit date: | 2022-10-11 | Release date: | 2023-10-18 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis of Irgb6 inactivation by Toxoplasma gondii through the phosphorylation of switch I. Genes Cells, 29, 2024
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1V7N
| Human Thrombopoietin Functional Domain Complexed To Neutralizing Antibody TN1 Fab | Descriptor: | Monoclonal TN1 Fab Heavy Chain, Monoclonal TN1 Fab Light Chain, Thrombopoietin | Authors: | Feese, M.D, Tamada, T, Kato, Y, Maeda, Y, Hirose, M, Matsukura, Y, Shigematsu, H, Kato, T, Miyazaki, H, Kuroki, R. | Deposit date: | 2003-12-18 | Release date: | 2004-03-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment Proc.Natl.Acad.Sci.USA, 101, 2004
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8HLB
| Cryo-EM structure of biparatopic antibody Bp109-92 in complex with TNFR2 | Descriptor: | TR109 heavy chain, TR109 light chain, TR92 heavy chain, ... | Authors: | Akiba, H, Fujita, J, Ise, T, Nishiyama, K, Miyata, T, Kato, T, Namba, K, Ohno, H, Kamada, H, Nagata, S, Tsumoto, K. | Deposit date: | 2022-11-29 | Release date: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (3.63 Å) | Cite: | Development of a 1:1-binding biparatopic anti-TNFR2 antagonist by reducing signaling activity through epitope selection. Commun Biol, 6, 2023
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8H4M
| Crystal Structure of GTP-bound Irgb6_T95D mutant | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, T-cell-specific guanine nucleotide triphosphate-binding protein 2 | Authors: | Saijo-Hamano, Y, Okuma, H, Sakai, N, Kato, T, Imasaki, T, Nitta, R. | Deposit date: | 2022-10-10 | Release date: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural basis of Irgb6 inactivation by Toxoplasma gondii through the phosphorylation of switch I To Be Published
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8BVS
| Cryo-EM structure of rat SLC22A6 bound to tenofovir | Descriptor: | CHLORIDE ION, Solute carrier family 22 member 6, Synthetic nanobody (Sybody), ... | Authors: | Parker, J.L, Kato, T, Newstead, S. | Deposit date: | 2022-12-05 | Release date: | 2023-07-19 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.61 Å) | Cite: | Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1. Nat.Struct.Mol.Biol., 30, 2023
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8BVR
| Cryo-EM structure of rat SLC22A6 in the apo state | Descriptor: | PHOSPHATE ION, Solute carrier family 22 member 6, Synthetic nanobody (Sybody) | Authors: | Parker, J.L, Kato, T, Newstead, S. | Deposit date: | 2022-12-05 | Release date: | 2023-07-19 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1. Nat.Struct.Mol.Biol., 30, 2023
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8BVT
| Cryo-EM structure of rat SLC22A6 bound to probenecid | Descriptor: | 4-(dipropylsulfamoyl)benzoic acid, Solute carrier family 22 member 6, Synthetic nanobody (Sybody) | Authors: | Parker, J.L, Kato, T, Newstead, S. | Deposit date: | 2022-12-06 | Release date: | 2023-07-19 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.94 Å) | Cite: | Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1. Nat.Struct.Mol.Biol., 30, 2023
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