8H4O
Crystal Structure of nucleotide-free Irgb6_T95D mutant
Summary for 8H4O
| Entry DOI | 10.2210/pdb8h4o/pdb |
| Descriptor | T-cell-specific guanine nucleotide triphosphate-binding protein 2 (2 entities in total) |
| Functional Keywords | toxoplasma gondii, pv, irg, gtpase, hydrolase, immune system |
| Biological source | Mus musculus (house mouse) |
| Total number of polymer chains | 2 |
| Total formula weight | 94689.41 |
| Authors | Saijo-Hamano, Y.,Okuma, H.,Sakai, N.,Kato, T.,Imasaki, T.,Nitta, R. (deposition date: 2022-10-11, release date: 2023-10-18, Last modification date: 2024-07-03) |
| Primary citation | Okuma, H.,Saijo-Hamano, Y.,Yamada, H.,Sherif, A.A.,Hashizaki, E.,Sakai, N.,Kato, T.,Imasaki, T.,Kikkawa, S.,Nitta, E.,Sasai, M.,Abe, T.,Sugihara, F.,Maniwa, Y.,Kosako, H.,Takei, K.,Standley, D.M.,Yamamoto, M.,Nitta, R. Structural basis of Irgb6 inactivation by Toxoplasma gondii through the phosphorylation of switch I. Genes Cells, 29:17-38, 2024 Cited by PubMed: 37984375DOI: 10.1111/gtc.13080 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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