7VR8
Inward-facing structure of human EAAT2 in the substrate-free state
Summary for 7VR8
| Entry DOI | 10.2210/pdb7vr8/pdb |
| EMDB information | 32098 |
| Descriptor | Excitatory amino acid transporter 2, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, CHOLESTEROL, ... (4 entities in total) |
| Functional Keywords | transporter, membrane protein, transport protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 65528.63 |
| Authors | Kato, T.,Kusakizako, T.,Yamashita, K.,Nishizawa, T.,Nureki, O. (deposition date: 2021-10-22, release date: 2022-08-10, Last modification date: 2022-09-28) |
| Primary citation | Kato, T.,Kusakizako, T.,Jin, C.,Zhou, X.,Ohgaki, R.,Quan, L.,Xu, M.,Okuda, S.,Kobayashi, K.,Yamashita, K.,Nishizawa, T.,Kanai, Y.,Nureki, O. Structural insights into inhibitory mechanism of human excitatory amino acid transporter EAAT2. Nat Commun, 13:4714-4714, 2022 Cited by PubMed: 35953475DOI: 10.1038/s41467-022-32442-6 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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