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7VR8

Inward-facing structure of human EAAT2 in the substrate-free state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AExcitatory amino acid transporter 2polymer58163016.91UniProt (P43004)
Pfam (PF00375)
In PDB
Homo sapiens (human)Glutamate/aspartate transporter II,Sodium-dependent glutamate/aspartate transporter 2,Solute carrier family 1 member 2
2A(3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-ennon-polymer544.81Chemie (9Z9)
3ACHOLESTEROLnon-polymer386.71Chemie (CLR)
4A1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINEnon-polymer790.12Chemie (PC1)
Sequence modifications
A: 1 - 574 (UniProt: P43004)
PDBExternal DatabaseDetails
Glu 575-expression tag
Asn 576-expression tag
Leu 577-expression tag
Tyr 578-expression tag
Phe 579-expression tag
Gln 580-expression tag
Gly 581-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight63016.9
Non-Polymers*Number of molecules4
Total formula weight2511.7
All*Total formula weight65528.6
*Water molecules are not included.

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PDB entries from 2024-10-09

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