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8H4M

Crystal Structure of GTP-bound Irgb6_T95D mutant

Summary for 8H4M
Entry DOI10.2210/pdb8h4m/pdb
DescriptorT-cell-specific guanine nucleotide triphosphate-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE (3 entities in total)
Functional Keywordstoxoplasma gondii, pv, irg, gtpase, hydrolase, immune system
Biological sourceMus musculus (house mouse)
Total number of polymer chains1
Total formula weight47867.88
Authors
Saijo-Hamano, Y.,Okuma, H.,Sakai, N.,Kato, T.,Imasaki, T.,Nitta, R. (deposition date: 2022-10-10, release date: 2023-10-18)
Primary citationOkuma, H.,Saijo-Hamano, Y.,Sherif, A.A.,Hashizaki, E.,Sakai, N.,Kato, K.,Imasaki, T.,Nitta, E.,Sasai, M.,Kosako, H.,Standley, D.M.,Yamamoto, M.,Nitta, R.
Structural basis of Irgb6 inactivation by Toxoplasma gondii through the phosphorylation of switch I
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.68 Å)
Structure validation

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