1LBQ
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![BU of 1lbq by Molmil](/molmil-images/mine/1lbq) | The crystal structure of Saccharomyces cerevisiae ferrochelatase | Descriptor: | Ferrochelatase | Authors: | Karlberg, T, Lecerof, D, Gora, M, Silvegren, G, Labbe-Bois, R, Hansson, M, Al-Karadaghi, S. | Deposit date: | 2002-04-04 | Release date: | 2002-11-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Metal binding to Saccharomyces cerevisiae ferrochelatase Biochemistry, 41, 2002
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2H1V
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![BU of 2h1v by Molmil](/molmil-images/mine/2h1v) | Crystal structure of the Lys87Ala mutant variant of Bacillus subtilis ferrochelatase | Descriptor: | Ferrochelatase, MAGNESIUM ION | Authors: | Hansson, M.D, Karlberg, T, Arys Rahardja, M, Al-Karadaghi, S, Hansson, M. | Deposit date: | 2006-05-17 | Release date: | 2007-01-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Amino Acid Residues His183 and Glu264 in Bacillus subtilis Ferrochelatase Direct and Facilitate the Insertion of Metal Ion into Protoporphyrin IX Biochemistry, 46, 2007
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3GOQ
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![BU of 3goq by Molmil](/molmil-images/mine/3goq) | |
1L8X
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![BU of 1l8x by Molmil](/molmil-images/mine/1l8x) | Crystal Structure of Ferrochelatase from the Yeast, Saccharomyces cerevisiae, with Cobalt(II) as the Substrate Ion | Descriptor: | COBALT (II) ION, Ferrochelatase | Authors: | Karlberg, T, Lecerof, D, Gora, M, Silvegren, G, Labbe-Bois, R, Hansson, M, Al-Karadaghi, S. | Deposit date: | 2002-03-22 | Release date: | 2002-11-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Metal Binding to Saccharomyces cerevisiae Ferrochelatase Biochemistry, 41, 2002
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2AC2
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![BU of 2ac2 by Molmil](/molmil-images/mine/2ac2) | Crystal structure of the Tyr13Phe mutant variant of Bacillus subtilis Ferrochelatase with Zn(2+) bound at the active site | Descriptor: | Ferrochelatase, ZINC ION | Authors: | Shipovskov, S, Karlberg, T, Fodje, M, Hansson, M.D, Ferreira, G.C, Hansson, M, Reimann, C.T, Al-Karadaghi, S. | Deposit date: | 2005-07-18 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Metallation of the Transition-state Inhibitor N-methyl Mesoporphyrin by Ferrochelatase: Implications for the Catalytic Reaction Mechanism. J.Mol.Biol., 352, 2005
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2AC4
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![BU of 2ac4 by Molmil](/molmil-images/mine/2ac4) | Crystal structure of the His183Cys mutant variant of Bacillus subtilis Ferrochelatase | Descriptor: | Ferrochelatase | Authors: | Shipovskov, S, Karlberg, T, Fodje, M, Hansson, M.D, Ferreira, G.C, Hansson, M, Reimann, C.T, Al-Karadaghi, S. | Deposit date: | 2005-07-18 | Release date: | 2005-09-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Metallation of the Transition-state Inhibitor N-methyl Mesoporphyrin by Ferrochelatase: Implications for the Catalytic Reaction Mechanism. J.Mol.Biol., 352, 2005
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1DAR
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![BU of 1dar by Molmil](/molmil-images/mine/1dar) | ELONGATION FACTOR G IN COMPLEX WITH GDP | Descriptor: | ELONGATION FACTOR G, GUANOSINE-5'-DIPHOSPHATE | Authors: | Al-Karadaghi, S, Aevarsson, A, Garber, M, Zheltonosova, J, Liljas, A. | Deposit date: | 1996-02-15 | Release date: | 1996-07-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The structure of elongation factor G in complex with GDP: conformational flexibility and nucleotide exchange. Structure, 4, 1996
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8SR0
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![BU of 8sr0 by Molmil](/molmil-images/mine/8sr0) | CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 local refined | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, favezelimab Fab heavy chain, ... | Authors: | Mishra, A.K, Shahid, S, Karade, S.S, Mariuzza, R.A. | Deposit date: | 2023-05-05 | Release date: | 2023-09-06 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker. Structure, 31, 2023
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8SO3
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![BU of 8so3 by Molmil](/molmil-images/mine/8so3) | CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, favezelimab Fab heavy chain, ... | Authors: | Mishra, A.K, Shahid, S, Karade, S.S, Mariuzza, R.A. | Deposit date: | 2023-04-28 | Release date: | 2023-09-06 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.61 Å) | Cite: | CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker. Structure, 31, 2023
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2OXI
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![BU of 2oxi by Molmil](/molmil-images/mine/2oxi) | |
4BP3
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![BU of 4bp3 by Molmil](/molmil-images/mine/4bp3) | Crystal Structure of Plasmodium Falciparum Spermidine Synthase in Complex with DECARBOXYLATED S-ADENOSYLMETHIONINE5' AND 4- METHYLANILINE | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 4-METHYLANILINE, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, ... | Authors: | Sprenger, J, Halander, J.C, Svensson, B, Al-Karadaghi, S, Persson, L. | Deposit date: | 2013-05-23 | Release date: | 2014-06-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design Acta Crystallogr.,Sect.D, 71, 2015
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2PT6
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![BU of 2pt6 by Molmil](/molmil-images/mine/2pt6) | The structure of Plasmodium falciparum spermidine synthase in complex with decarboxylated S-adenosylmethionine | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, GLYCEROL, ... | Authors: | Dufe, V.T, Qiu, W, Muller, I.B, Hui, R, Walter, R.D, Al-Karadaghi, S, Structural Genomics Consortium (SGC) | Deposit date: | 2007-05-08 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO. J.Mol.Biol., 373, 2007
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2OHX
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2PT9
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![BU of 2pt9 by Molmil](/molmil-images/mine/2pt9) | The structure of Plasmodium falciparum spermidine synthase in complex with decarboxylated S-adenosylmethionine and the inhibitor cis-4-methylcyclohexylamine (4MCHA) | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, GLYCEROL, ... | Authors: | Dufe, V.T, Qiu, W, Muller, I.B, Hui, R, Walter, R.D, Al-Karadaghi, S, Structural Genomics Consortium (SGC) | Deposit date: | 2007-05-08 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO. J.Mol.Biol., 373, 2007
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3RIE
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![BU of 3rie by Molmil](/molmil-images/mine/3rie) | The structure of Plasmodium falciparum spermidine synthase in complex with 5'-methylthioadenosine and N-(3-aminopropyl)-trans-cyclohexane-1,4-diamine | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL, ... | Authors: | Williams, M, Sprenger, J, Persson, L, Louw, A.I, Birkholtz, L, Al-Karadaghi, S. | Deposit date: | 2011-04-13 | Release date: | 2012-04-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A novel inhibitor of Plasmodium falciparum spermidine synthase: a twist in the tail. Malar J, 14, 2015
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1C9E
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![BU of 1c9e by Molmil](/molmil-images/mine/1c9e) | STRUCTURE OF FERROCHELATASE WITH COPPER(II) N-METHYLMESOPORPHYRIN COMPLEX BOUND AT THE ACTIVE SITE | Descriptor: | MAGNESIUM ION, N-METHYLMESOPORPHYRIN CONTAINING COPPER, PROTOHEME FERROLYASE | Authors: | Lecerof, D, Fodje, M.N, Hansson, A, Hansson, M, Al-Karadaghi, S. | Deposit date: | 1999-08-02 | Release date: | 2000-03-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and mechanistic basis of porphyrin metallation by ferrochelatase. J.Mol.Biol., 297, 2000
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1C1H
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![BU of 1c1h by Molmil](/molmil-images/mine/1c1h) | CRYSTAL STRUCTURE OF BACILLUS SUBTILIS FERROCHELATASE IN COMPLEX WITH N-METHYL MESOPORPHYRIN | Descriptor: | FERROCHELATASE, MAGNESIUM ION, N-METHYLMESOPORPHYRIN | Authors: | Lecerof, D, Fodje, M, Hansson, A, Hansson, M, Al-Karadaghi, S. | Deposit date: | 1999-07-22 | Release date: | 2000-03-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and mechanistic basis of porphyrin metallation by ferrochelatase. J.Mol.Biol., 297, 2000
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2PSS
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![BU of 2pss by Molmil](/molmil-images/mine/2pss) | The structure of Plasmodium falciparum spermidine synthase in its apo-form | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, GLYCEROL, SULFATE ION, ... | Authors: | Dufe, V.T, Qiu, W, Muller, I.B, Hui, R, Walter, R.D, Al-Karadaghi, S, Structural Genomics Consortium (SGC) | Deposit date: | 2007-05-07 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO. J.Mol.Biol., 373, 2007
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1DD5
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![BU of 1dd5 by Molmil](/molmil-images/mine/1dd5) | CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA RIBOSOME RECYCLING FACTOR, RRF | Descriptor: | ACETIC ACID, RIBOSOME RECYCLING FACTOR | Authors: | Selmer, M, Al-Karadaghi, S, Hirokawa, G, Kaji, A, Liljas, A. | Deposit date: | 1999-11-08 | Release date: | 1999-12-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystal structure of Thermotoga maritima ribosome recycling factor: a tRNA mimic. Science, 286, 1999
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1DOZ
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![BU of 1doz by Molmil](/molmil-images/mine/1doz) | CRYSTAL STRUCTURE OF FERROCHELATASE | Descriptor: | FERROCHELATASE, MAGNESIUM ION | Authors: | Lecerof, D, Fodje, M, Hansson, A, Hansson, M, Al-Karadaghi, S. | Deposit date: | 1999-12-22 | Release date: | 2000-01-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and mechanistic basis of porphyrin metallation by ferrochelatase. J.Mol.Biol., 297, 2000
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4BP1
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![BU of 4bp1 by Molmil](/molmil-images/mine/4bp1) | Crystal Structure of Plasmodium Falciparum Spermidine Synthase in Complex with 5'-Methylthioadenosine and Putrescine | Descriptor: | 1,4-DIAMINOBUTANE, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 5'-DEOXY-5'-METHYLTHIOADENOSINE, ... | Authors: | Sprenger, J, Halander, J.C, Svensson, B, Al-Karadaghi, S, Persson, L. | Deposit date: | 2013-05-23 | Release date: | 2014-06-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design Acta Crystallogr.,Sect.D, 71, 2015
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2B2C
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![BU of 2b2c by Molmil](/molmil-images/mine/2b2c) | Cloning, expression, characterisation and three- dimensional structure determination of the Caenorhabditis elegans spermidine synthase | Descriptor: | spermidine synthase | Authors: | Dufe, V.T, Luersen, K, Eschbach, M.L, Haider, N, Karlberg, T, Walter, R.D, Al-Karadaghi, S. | Deposit date: | 2005-09-19 | Release date: | 2005-11-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Cloning, expression, characterisation and three-dimensional structure determination of Caenorhabditis elegans spermidine synthase FEBS LETT., 579, 2005
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4CXM
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![BU of 4cxm by Molmil](/molmil-images/mine/4cxm) | Crystal Structure of Plasmodium Falciparum Spermidine Synthase in Complex with METHYLTHIOADENOSIN AND SPERMIDINE after catalysis in crystal | Descriptor: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, SPERMIDINE, SPERMIDINE SYNTHASE | Authors: | Sprenger, J, Svensson, B, Al-Karadaghi, S, Persson, L. | Deposit date: | 2014-04-07 | Release date: | 2014-10-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design. Acta Crystallogr.,Sect.D, 71, 2015
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5ANM
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![BU of 5anm by Molmil](/molmil-images/mine/5anm) | Crystal structure of IgE Fc in complex with a neutralizing antibody | Descriptor: | IG EPSILON CHAIN C REGION, IMMUNOGLOBULIN G, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Cohen, E.S, Dobson, C.L, Kack, H, Wang, B, Sims, D.A, Lloyd, C.O, England, E, Rees, D.G, Guo, H, Karagiannis, S.N, O'Brien, S, Persdotter, S, Ekdahl, H, Butler, R, Keyes, F, Oakley, S, Carlsson, M, Briend, E, Wilkinson, T, Anderson, I.K, Monk, P.D, vonWachenfeldt, K, Eriksson, P.O, Gould, H.J, Vaughan, T.J, May, R.D. | Deposit date: | 2015-09-07 | Release date: | 2015-09-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | A Novel Ige-Neutralizing Antibody for the Treatment of Severe Uncontrolled Asthma. Mabs, 6, 2015
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1LD3
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![BU of 1ld3 by Molmil](/molmil-images/mine/1ld3) | Crystal Structure of B. subilis ferrochelatase with Zn(2+) bound at the active site. | Descriptor: | Ferrochelatase, ZINC ION | Authors: | Lecerof, D, Fodje, M.N, Leon, R.A, Olsson, U, Hansson, A, Sigfridsson, E, Ryde, U, Hansson, M, Al-Karadaghi, S. | Deposit date: | 2002-04-08 | Release date: | 2003-05-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Metal binding to Bacillus subtilis ferrochelatase and interaction between metal sites J.Biol.Inorg.Chem., 8, 2003
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