4BP1

Crystal Structure of Plasmodium Falciparum Spermidine Synthase in Complex with 5'-Methylthioadenosine and Putrescine

Summary for 4BP1

Entry DOI	10.2210/pdb4bp1/pdb
Related	4BP3
Descriptor	SPERMIDINE SYNTHASE, 5'-DEOXY-5'-METHYLTHIOADENOSINE, 1,4-DIAMINOBUTANE, ... (6 entities in total)
Functional Keywords	transferase, aminopropyl transferase, polyamine pathway, rossmann-like fold
Biological source	PLASMODIUM FALCIPARUM
Total number of polymer chains	3
Total formula weight	98164.30
Authors	Sprenger, J.,Halander, J.C.,Svensson, B.,Al-Karadaghi, S.,Persson, L. (deposition date: 2013-05-23, release date: 2014-06-04, Last modification date: 2023-12-20)
Primary citation	Sprenger, J.,Svensson, B.,Halander, J.,Carey, J.,Persson, L.,Al-Karadaghi, S. Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design Acta Crystallogr.,Sect.D, 71:484-, 2015 Cited by PubMed: 25760598 DOI: 10.1107/S1399004714027011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.17 Å)

Structure validation