4BP3
Crystal Structure of Plasmodium Falciparum Spermidine Synthase in Complex with DECARBOXYLATED S-ADENOSYLMETHIONINE5' AND 4- METHYLANILINE
Summary for 4BP3
Entry DOI | 10.2210/pdb4bp3/pdb |
Related | 4BP1 |
Descriptor | SPERMIDINE SYNTHASE, 4-METHYLANILINE, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, ... (6 entities in total) |
Functional Keywords | transferase, aminopropyl transferase, polyamine pathway, rossmann-like fold |
Biological source | PLASMODIUM FALCIPARUM |
Total number of polymer chains | 3 |
Total formula weight | 98650.95 |
Authors | Sprenger, J.,Halander, J.C.,Svensson, B.,Al-Karadaghi, S.,Persson, L. (deposition date: 2013-05-23, release date: 2014-06-25, Last modification date: 2023-12-20) |
Primary citation | Sprenger, J.,Svensson, B.,Halander, J.,Carey, J.,Persson, L.,Al-Karadaghi, S. Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design Acta Crystallogr.,Sect.D, 71:484-, 2015 Cited by PubMed: 25760598DOI: 10.1107/S1399004714027011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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