2PSS

The structure of Plasmodium falciparum spermidine synthase in its apo-form

Summary for 2PSS

Entry DOI	10.2210/pdb2pss/pdb
Related	2HTE 2I7C
Descriptor	Spermidine synthase, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, GLYCEROL, ... (5 entities in total)
Functional Keywords	transferase, spermidine synthase, structural genomics consortium, sgc, structural biology of malarial parasites and other apicomplexans
Biological source	Plasmodium falciparum
Total number of polymer chains	3
Total formula weight	110798.35
Authors	Dufe, V.T.,Qiu, W.,Muller, I.B.,Hui, R.,Walter, R.D.,Al-Karadaghi, S.,Structural Genomics Consortium (SGC) (deposition date: 2007-05-07, release date: 2008-04-01, Last modification date: 2023-08-30)
Primary citation	Dufe, V.T.,Qiu, W.,Muller, I.B.,Hui, R.,Walter, R.D.,Al-Karadaghi, S. Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO. J.Mol.Biol., 373:167-177, 2007 Cited by PubMed: 17822713 DOI: 10.1016/j.jmb.2007.07.053 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation