2PSS
The structure of Plasmodium falciparum spermidine synthase in its apo-form
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0004766 | molecular_function | spermidine synthase activity |
A | 0005829 | cellular_component | cytosol |
A | 0006596 | biological_process | polyamine biosynthetic process |
A | 0008295 | biological_process | spermidine biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
B | 0003824 | molecular_function | catalytic activity |
B | 0004766 | molecular_function | spermidine synthase activity |
B | 0005829 | cellular_component | cytosol |
B | 0006596 | biological_process | polyamine biosynthetic process |
B | 0008295 | biological_process | spermidine biosynthetic process |
B | 0016740 | molecular_function | transferase activity |
C | 0003824 | molecular_function | catalytic activity |
C | 0004766 | molecular_function | spermidine synthase activity |
C | 0005829 | cellular_component | cytosol |
C | 0006596 | biological_process | polyamine biosynthetic process |
C | 0008295 | biological_process | spermidine biosynthetic process |
C | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 B 604 |
Chain | Residue |
B | HIS236 |
B | GLY238 |
B | THR239 |
B | LYS291 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE 1PG A 701 |
Chain | Residue |
A | TRP43 |
A | SER45 |
A | PHE47 |
A | SER57 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE 1PG B 702 |
Chain | Residue |
B | PHE47 |
C | TRP43 |
C | SER45 |
C | PHE47 |
C | SER57 |
B | TRP43 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL B 601 |
Chain | Residue |
B | LYS97 |
B | PHE100 |
B | LYS297 |
C | TRP234 |
C | HOH637 |
site_id | AC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL C 602 |
Chain | Residue |
B | TRP234 |
B | PHE313 |
B | HOH728 |
C | LYS97 |
site_id | AC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE GOL A 603 |
Chain | Residue |
A | LYS97 |
A | TRP234 |
A | HOH750 |
Functional Information from PROSITE/UniProt
site_id | PS01330 |
Number of Residues | 14 |
Details | PABS_1 Polyamine biosynthesis (PABS) domain signature. VLVVGGGdGgiIrE |
Chain | Residue | Details |
A | VAL120-GLU133 |