2PSS
The structure of Plasmodium falciparum spermidine synthase in its apo-form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004766 | molecular_function | spermidine synthase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006596 | biological_process | polyamine biosynthetic process |
| A | 0008295 | biological_process | spermidine biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004766 | molecular_function | spermidine synthase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006596 | biological_process | polyamine biosynthetic process |
| B | 0008295 | biological_process | spermidine biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004766 | molecular_function | spermidine synthase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006596 | biological_process | polyamine biosynthetic process |
| C | 0008295 | biological_process | spermidine biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 604 |
| Chain | Residue |
| B | HIS236 |
| B | GLY238 |
| B | THR239 |
| B | LYS291 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE 1PG A 701 |
| Chain | Residue |
| A | TRP43 |
| A | SER45 |
| A | PHE47 |
| A | SER57 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 1PG B 702 |
| Chain | Residue |
| B | PHE47 |
| C | TRP43 |
| C | SER45 |
| C | PHE47 |
| C | SER57 |
| B | TRP43 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 601 |
| Chain | Residue |
| B | LYS97 |
| B | PHE100 |
| B | LYS297 |
| C | TRP234 |
| C | HOH637 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL C 602 |
| Chain | Residue |
| B | TRP234 |
| B | PHE313 |
| B | HOH728 |
| C | LYS97 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 603 |
| Chain | Residue |
| A | LYS97 |
| A | TRP234 |
| A | HOH750 |
Functional Information from PROSITE/UniProt
| site_id | PS01330 |
| Number of Residues | 14 |
| Details | PABS_1 Polyamine biosynthesis (PABS) domain signature. VLVVGGGdGgiIrE |
| Chain | Residue | Details |
| A | VAL120-GLU133 |
