2HTE

The crystal structure of spermidine synthase from p. falciparum in complex with 5'-methylthioadenosine

Summary for 2HTE

• Entry DOI: 10.2210/pdb2hte/pdb
• Related: 1ZDZ
• Descriptor: Spermidine synthase, UNKNOWN ATOM OR ION, 5'-DEOXY-5'-METHYLTHIOADENOSINE, ... (6 entities in total)
• Functional Keywords: transferase, spermidine synthase, structural genomics consortium, sgc
• Biological source: Plasmodium falciparum
• Total number of polymer chains: 3
• Total formula weight: 98156.13

Authors

Qiu, W.,Dong, A.,Ren, H.,Wu, H.,Wasney, G.,Vedadi, M.,Lew, J.,Kozieradski, I.,Edwards, A.M.,Arrowsmith, C.H.,Weigelt, J.,Sundstrom, M.,Plotnikov, A.N.,Bochkarev, A.,Hui, R.,Structural Genomics Consortium (SGC) (deposition date: 2006-07-25, release date: 2006-08-08, Last modification date: 2023-08-30)

• Primary citation: Vedadi, M.,Lew, J.,Artz, J.,Amani, M.,Zhao, Y.,Dong, A.,Wasney, G.A.,Gao, M.,Hills, T.,Brokx, S.,Qiu, W.,Sharma, S.,Diassiti, A.,Alam, Z.,Melone, M.,Mulichak, A.,Wernimont, A.,Bray, J.,Loppnau, P.,Plotnikova, O.,Newberry, K.,Sundararajan, E.,Houston, S.,Walker, J.,Tempel, W.,Bochkarev, A.,Kozieradzki, I.,Edwards, A.,Arrowsmith, C.,Roos, D.,Kain, K.,Hui, R.; Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.; Mol.Biochem.Parasitol., 151:100-110, 2007; PubMed: 17125854; DOI: 10.1016/j.molbiopara.2006.10.011

Experimental method

X-RAY DIFFRACTION (2 Å)