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2HTE

The crystal structure of spermidine synthase from p. falciparum in complex with 5'-methylthioadenosine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Spermidine synthasepolymer28332221.23UniProt (Q8II73)
Pfam (PF17284)
Pfam (PF01564)
Plasmodium falciparum
2D, F, H, I, J...
(A, B, C)
UNKNOWN ATOM OR IONnon-polymer13Chemie (UNX)
3E, M, S
(A, B, C)
5'-DEOXY-5'-METHYLTHIOADENOSINEnon-polymer297.33Chemie (MTA)
4G, U
(A, C)
2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOLnon-polymer252.32Chemie (1PG)
5K
(B)
SULFATE IONnon-polymer96.11Chemie (SO4)
6W, X, Y
(A, B, C)
waterwater18.0571Chemie (HOH)
Sequence modifications
A, B, C: 1 - 283 (UniProt: Q8II73)
PDBExternal DatabaseDetails
Gly 1-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight96663.5
Non-Polymers*Number of molecules19
Total formula weight1492.7
All*Total formula weight98156.1
*Water molecules are not included.

239803

PDB entries from 2025-08-06

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