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PDB: 157 件

3RIE
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The structure of Plasmodium falciparum spermidine synthase in complex with 5'-methylthioadenosine and N-(3-aminopropyl)-trans-cyclohexane-1,4-diamine
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL, ...
著者Williams, M, Sprenger, J, Persson, L, Louw, A.I, Birkholtz, L, Al-Karadaghi, S.
登録日2011-04-13
公開日2012-04-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A novel inhibitor of Plasmodium falciparum spermidine synthase: a twist in the tail.
Malar J, 14, 2015
2PSS
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The structure of Plasmodium falciparum spermidine synthase in its apo-form
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, GLYCEROL, SULFATE ION, ...
著者Dufe, V.T, Qiu, W, Muller, I.B, Hui, R, Walter, R.D, Al-Karadaghi, S, Structural Genomics Consortium (SGC)
登録日2007-05-07
公開日2008-04-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.
J.Mol.Biol., 373, 2007
4EC2
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Crystal structure of trimeric frataxin from the yeast Saccharomyces cerevisiae, complexed with ferrous
分子名称: FE (II) ION, Frataxin homolog, mitochondrial
著者Soderberg, C.A.G, Rajan, S, Gakh, O, Isaya, G, Al-Karadaghi, S.
登録日2012-03-26
公開日2013-01-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.002 Å)
主引用文献The molecular basis of iron-induced oligomerization of frataxin and the role of the ferroxidation reaction in oligomerization.
J.Biol.Chem., 288, 2013
8TI5
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Crystal structure of Tyr p 36.0101
分子名称: Profilin, SULFATE ION
著者O'Malley, A, Sankaran, S, Chruszcz, M.
登録日2023-07-19
公開日2024-05-08
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structural homology of mite profilins to plant profilins is not indicative of allergic cross-reactivity.
Biol.Chem., 405, 2024
4OPH
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X-ray structure of full-length H6N6 NS1
分子名称: Nonstructural protein 1
著者Carrillo, B, Choi, J.M, Bornholdt, Z.A, Sankaran, S, Rice, A.P, Prasad, B.V.V.
登録日2014-02-05
公開日2014-02-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.158 Å)
主引用文献The Influenza A Virus Protein NS1 Displays Structural Polymorphism.
J.Virol., 88, 2014
8TI6
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Crystal structure of Tyr p 36.0101
分子名称: Profilin, Proline-rich peptide, SULFATE ION
著者O'Malley, A, Sankaran, S, Chruszcz, M.
登録日2023-07-19
公開日2024-05-08
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Structural homology of mite profilins to plant profilins is not indicative of allergic cross-reactivity.
Biol.Chem., 405, 2024
2PT6
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The structure of Plasmodium falciparum spermidine synthase in complex with decarboxylated S-adenosylmethionine
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, GLYCEROL, ...
著者Dufe, V.T, Qiu, W, Muller, I.B, Hui, R, Walter, R.D, Al-Karadaghi, S, Structural Genomics Consortium (SGC)
登録日2007-05-08
公開日2008-04-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.
J.Mol.Biol., 373, 2007
2OXI
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REFINED CRYSTAL STRUCTURE OF CU-SUBSTITUTED ALCOHOL DEHYDROGENASE AT 2.1 ANGSTROMS RESOLUTION
分子名称: ALCOHOL DEHYDROGENASE, COPPER (II) ION, DIMETHYL SULFOXIDE, ...
著者Al-Karadaghi, S, Cedergren-Zeppezauer, E.S.
登録日1993-11-08
公開日1994-01-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Refined structure of Cu-substituted alcohol dehydrogenase at 2.1 A resolution.
Acta Crystallogr.,Sect.D, 51, 1995
2OHX
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REFINED CRYSTAL STRUCTURE OF LIVER ALCOHOL DEHYDROGENASE-NADH COMPLEX AT 1.8 ANGSTROMS RESOLUTION
分子名称: ALCOHOL DEHYDROGENASE, DIMETHYL SULFOXIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Al-Karadaghi, S, Cedergren-Zeppezauer, E.S.
登録日1993-08-24
公開日1993-10-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Refined crystal structure of liver alcohol dehydrogenase-NADH complex at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 50, 1994
2PT9
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The structure of Plasmodium falciparum spermidine synthase in complex with decarboxylated S-adenosylmethionine and the inhibitor cis-4-methylcyclohexylamine (4MCHA)
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, GLYCEROL, ...
著者Dufe, V.T, Qiu, W, Muller, I.B, Hui, R, Walter, R.D, Al-Karadaghi, S, Structural Genomics Consortium (SGC)
登録日2007-05-08
公開日2008-04-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.
J.Mol.Biol., 373, 2007
8TI7
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BU of 8ti7 by Molmil
Crystal structure of profilin from Dermatophagoides pteronyssinus in complex with a poly(L-proline) peptide
分子名称: Profilin, SULFATE ION, poly(L-proline)
著者O'Malley, A, Sankaran, S, Chruszcz, M.
登録日2023-07-19
公開日2024-05-08
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.397 Å)
主引用文献Structural homology of mite profilins to plant profilins is not indicative of allergic cross-reactivity.
Biol.Chem., 405, 2024
6R0I
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BU of 6r0i by Molmil
Glycogen Phosphorylase b in complex with 4
分子名称: Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, ...
著者Koulas, M.S, Tsagkarakou, S.A, Kyriakis, E, Stravodimos, G.A, Skamnaki, V.T, Leonidas, D.D.
登録日2019-03-13
公開日2019-04-17
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl-N-acyl-beta-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors.
Molecules, 24, 2019
1XSS
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BU of 1xss by Molmil
Semi-rational engineering of a green-emitting coral fluorescent protein into an efficient highlighter.
分子名称: MAGNESIUM ION, SODIUM ION, fluorescent protein
著者Tsutsui, H, Karasawa, S, Shimizu, H, Nukina, N, Miyawaki, A.
登録日2004-10-20
公開日2005-03-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Semi-rational engineering of a coral fluorescent protein into an efficient highlighter
Embo Rep., 6, 2005
7DGX
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Structure of coiled coil domain of Trypanosoma brucei coronin
分子名称: Coronin
著者Parihar, P.S, Karade, S.S, Pratap, J.V.
登録日2020-11-12
公開日2021-11-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Structural insights into kinetoplastid coronin oligomerization domain and F-actin interaction
Curr Res Struct Biol, 3, 2021
2ZO7
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Crystal Structure of a Kusabira-Cyan Mutant (KCY-R1), a Cyan/Green-Emitting GFP-Like Protein
分子名称: CYAN/GREEN-EMITTING GFP-LIKE PROTEIN, KUSABIRA-CYAN MUTANT (KCY-R1)
著者Kikuchi, A, Fukumura, E, Karasawa, S, Miyawaki, A, Shiro, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-05-06
公開日2009-05-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal structure of a new cyan fluorescent protein and its hue-shifted variants
Biochemistry, 48, 2009
2ZO6
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Crystal Structure of Kusabira-Cyan (KCY), a Cyan-Emitting GFP-Like Protein
分子名称: CYAN-EMITTING GFP-LIKE PROTEIN, KUSABIRA-CYAN (KCY)
著者Kikuchi, A, Fukumura, E, Karasawa, S, Miyawaki, A, Shiro, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-05-06
公開日2009-05-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of a new cyan fluorescent protein and its hue-shifted variants
Biochemistry, 48, 2009
2ZMU
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Crystal Structure of Monomeric Kusabira-Orange (MKO), Orange-Emitting GFP-like Protein, at pH 9.1
分子名称: Fluorescent protein
著者Kikuchi, A, Fukumura, E, Karasawa, S, Mizuno, H, Miyawaki, A, Shiro, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-04-21
公開日2008-10-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Characterization of a Thiazoline-Containing Chromophore in an Orange Fluorescent Protein, Monomeric Kusabira Orange
Biochemistry, 47, 2008
5CX2
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Structure of coiled coil domain of Leishmania donovani coronin
分子名称: 1,2-ETHANEDIOL, Coronin, SULFATE ION
著者Nayak, A.R, Karade, S.S, Srivastava, V.K, Pratap, J.V.
登録日2015-07-28
公開日2016-07-27
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structure of Leishmania donovani coronin coiled coil domain reveals an antiparallel 4 helix bundle with inherent asymmetry
J.Struct.Biol., 195, 2016
2ZMW
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Crystal Structure of Monomeric Kusabira-Orange (MKO), Orange-Emitting GFP-like Protein, at pH 6.0
分子名称: Fluorescent protein
著者Kikuchi, A, Fukumura, E, Karasawa, S, Mizuno, H, Miyawaki, A, Shiro, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-04-21
公開日2008-10-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Characterization of a Thiazoline-Containing Chromophore in an Orange Fluorescent Protein, Monomeric Kusabira Orange
Biochemistry, 47, 2008
8SO3
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CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, favezelimab Fab heavy chain, ...
著者Mishra, A.K, Shahid, S, Karade, S.S, Mariuzza, R.A.
登録日2023-04-28
公開日2023-09-06
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker.
Structure, 31, 2023
8SR0
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CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 local refined
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, favezelimab Fab heavy chain, ...
著者Mishra, A.K, Shahid, S, Karade, S.S, Mariuzza, R.A.
登録日2023-05-05
公開日2023-09-06
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker.
Structure, 31, 2023
2FOY
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Human Carbonic Anhydrase I complexed with a two-prong inhibitor
分子名称: Carbonic anhydrase 1, ZINC ION, {2,2'-[(2-{[4-(AMINOSULFONYL)BENZOYL]AMINO}ETHYL)IMINO]DIACETATO(2-)-KAPPAO}COPPER
著者Jude, K.M, Banerjee, A.L, Haldar, M.K, Manokaran, S, Roy, B, Mallik, S, Srivastava, D.K, Christianson, D.W.
登録日2006-01-14
公開日2006-04-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Ultrahigh resolution crystal structures of human carbonic anhydrases I and II complexed with two-prong inhibitors reveal the molecular basis of high affinity.
J.Am.Chem.Soc., 128, 2006
3BEO
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A Structural Basis for the allosteric regulation of non-hydrolyzing UDP-GlcNAc 2-epimerases
分子名称: UDP-N-acetylglucosamine 2-epimerase, URIDINE-5'-DIPHOSPHATE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
著者Velloso, L.M, Bhaskaran, S.S, Schuch, R, Fischetti, V.A, Stebbins, C.E.
登録日2007-11-19
公開日2008-02-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A structural basis for the allosteric regulation of non-hydrolysing UDP-GlcNAc 2-epimerases.
Embo Rep., 9, 2008
2KJI
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A divergent ins protein in c. elegans structurally resemble insulin and activates the human insulin receptor
分子名称: Probable insulin-like peptide beta-type 5
著者Hua, Q.X, Nakarawa, S.H, Wilken, R, Ramos, R.R, Jia, W.H, Bass, J, Weiss, M.A.
登録日2009-05-28
公開日2009-06-16
最終更新日2024-10-16
実験手法SOLUTION NMR
主引用文献A divergent INS protein in Caenorhabditis elegans structurally resembles human insulin and activates the human insulin receptor.
Genes Dev., 17, 2003
2OP7
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WW4
分子名称: NEDD4-like E3 ubiquitin-protein ligase WWP1
著者Qin, H.N, Li, M.F, Pu, H, Sankaran, S, Ahmed, S, Song, J.X.
登録日2007-01-27
公開日2007-12-11
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献NMR structure of the forth WW domain of WWP1
To be Published

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