2KJI
A divergent ins protein in c. elegans structurally resemble insulin and activates the human insulin receptor
Summary for 2KJI
| Entry DOI | 10.2210/pdb2kji/pdb |
| Related | 4INS |
| Descriptor | Probable insulin-like peptide beta-type 5 (1 entity in total) |
| Functional Keywords | hormone, insulin like peptide, c. elegans, folding, ins-6, cleavage on pair of basic residues, disulfide bond, secreted |
| Biological source | Caenorhabditis elegans (nematode) |
| Total number of polymer chains | 1 |
| Total formula weight | 5304.07 |
| Authors | Hua, Q.X.,Nakarawa, S.H.,Wilken, R.,Ramos, R.R.,Jia, W.H.,Bass, J.,Weiss, M.A. (deposition date: 2009-05-28, release date: 2009-06-16, Last modification date: 2019-09-18) |
| Primary citation | Hua, Q.X.,Nakagawa, S.H.,Wilken, J.,Ramos, R.R.,Jia, W.,Bass, J.,Weiss, M.A. A divergent INS protein in Caenorhabditis elegans structurally resembles human insulin and activates the human insulin receptor. Genes Dev., 17:826-831, 2003 Cited by PubMed: 12654724DOI: 10.1101/gad.1058003 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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