6NIR
 
 | | Crystal structure of a GII.4 norovirus HOV protease | | Descriptor: | HOV protease, HOV protease fragment | | Authors: | Prasad, B.V.V, Hu, L. | | Deposit date: | 2018-12-31 | | Release date: | 2019-01-23 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.704 Å) | | Cite: | GII.4 Norovirus Protease Shows pH-Sensitive Proteolysis with a Unique Arg-His Pairing in the Catalytic Site.
J. Virol., 93, 2019
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8TKA
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8TL8
 | | Structure of Orthoreovirus RNA Chaperone SigmaNS R6A mutant in complex with bile acid | | Descriptor: | GLYCOCHOLIC ACID, Protein sigma-NS | | Authors: | Prasad, B.V.V, Zhao, B, Hu, L, Neetu, N. | | Deposit date: | 2023-07-26 | | Release date: | 2024-03-06 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure of orthoreovirus RNA chaperone sigma NS, a component of viral replication factories.
Nat Commun, 15, 2024
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8TL1
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4IMZ
 | | Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus | | Descriptor: | Genome polyprotein, SODIUM ION, THIOCYANATE ION, ... | | Authors: | Prasad, B.V.V, Muhaxhiri, Z, Deng, L, Shanker, S, Sankaran, B, Estes, M.K, Palzkill, T, Song, Y. | | Deposit date: | 2013-01-03 | | Release date: | 2013-02-20 | | Last modified: | 2013-04-10 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural basis of substrate specificity and protease inhibition in norwalk virus.
J.Virol., 87, 2013
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4IN1
 | | Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus | | Descriptor: | 3C-like protease, SULFATE ION | | Authors: | Prasad, B.V.V, Muhaxhiri, Z, Deng, L, Shanker, S, Sankaran, B, Estes, M.K, Palzkill, T, Song, Y. | | Deposit date: | 2013-01-03 | | Release date: | 2013-02-20 | | Last modified: | 2020-01-29 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural basis of substrate specificity and protease inhibition in norwalk virus.
J.Virol., 87, 2013
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4IN2
 | | Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus | | Descriptor: | C-like protease | | Authors: | Prasad, B.V.V, Muhaxhiri, Z, Deng, L, Shanker, S, Sankaran, B, Estes, M.K, Palzkill, T, Song, Y. | | Deposit date: | 2013-01-03 | | Release date: | 2013-02-20 | | Last modified: | 2013-04-10 | | Method: | X-RAY DIFFRACTION (2.401 Å) | | Cite: | Structural basis of substrate specificity and protease inhibition in norwalk virus.
J.Virol., 87, 2013
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4INH
 | | Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus | | Descriptor: | DIMETHYL SULFOXIDE, Genome polyprotein, peptide inhibitor, ... | | Authors: | Prasad, B.V.V, Muhaxhiri, Z, Deng, L, Shanker, S, Sankaran, B, Estes, M.K, Palzkill, T, Song, Y. | | Deposit date: | 2013-01-04 | | Release date: | 2013-02-20 | | Last modified: | 2013-04-10 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural basis of substrate specificity and protease inhibition in norwalk virus.
J.Virol., 87, 2013
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4IMQ
 | | Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus | | Descriptor: | 3C-like protease, PEPTIDE INHIBITOR, syc8, ... | | Authors: | Prasad, B.V.V, Muhaxhiri, Z, Deng, L, Shanker, S, Sankaran, B, Estes, M.K, Palzkill, T, Song, Y. | | Deposit date: | 2013-01-03 | | Release date: | 2013-02-20 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural basis of substrate specificity and protease inhibition in norwalk virus.
J.Virol., 87, 2013
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8G0W
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6XQR
 | | OXA-48 bound by Compound 2.2 | | Descriptor: | Beta-lactamase, CHLORIDE ION, [1,1'-biphenyl]-4,4'-disulfonic acid | | Authors: | Taylor, D.M, Hu, L, Prasad, B.V.V, Palzkill, T. | | Deposit date: | 2020-07-10 | | Release date: | 2021-12-15 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of Escherichia coli Producing OXA-48.
Acs Infect Dis., 7, 2021
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7R6Z
 | | OXA-48 bound by Compound 3.3 | | Descriptor: | 1,2-ETHANEDIOL, 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid, Beta-lactamase, ... | | Authors: | Taylor, D.M, Hu, L, Prasad, B.V.V, Sankaran, B, Palzkill, T. | | Deposit date: | 2021-06-24 | | Release date: | 2021-12-01 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of Escherichia coli Producing OXA-48.
Acs Infect Dis., 7, 2021
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8SJ3
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2GU0
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3F5T
 | | X-ray Structure of H5N1 NS1 | | Descriptor: | Nonstructural protein 1 | | Authors: | Bornholdt, Z.A, Prasad, B.V.V. | | Deposit date: | 2008-11-04 | | Release date: | 2008-11-25 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus
Nature, 456, 2008
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4WB4
 | | wt SA11 NSP4_CCD | | Descriptor: | CALCIUM ION, Non-structural glycoprotein NSP4 | | Authors: | Viskovska, M, Sastri, N.P, Hyser, J.M, Tanner, M.R, Horton, L.B, Sankaran, B, Prasad, B.V.V, Estes, M.K. | | Deposit date: | 2014-09-02 | | Release date: | 2014-09-24 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Structural Plasticity of the Coiled-Coil Domain of Rotavirus NSP4.
J.Virol., 88, 2014
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4WBA
 | | Q/E mutant SA11 NSP4_CCD | | Descriptor: | GLYCEROL, Non-structural glycoprotein NSP4, PHOSPHATE ION | | Authors: | Viskovska, M, Sastri, N.P, Hyser, J.M, Tanner, M.R, Horton, L.B, Sankaran, B, Prasad, B.V.V, Estes, M.K. | | Deposit date: | 2014-09-02 | | Release date: | 2014-09-24 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.799 Å) | | Cite: | Structural Plasticity of the Coiled-Coil Domain of Rotavirus NSP4.
J.Virol., 88, 2014
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2AEN
 | | Crystal structure of the rotavirus strain DS-1 VP8* core | | Descriptor: | ETHANOL, GLYCEROL, Outer capsid protein VP4, ... | | Authors: | Monnier, N, Higo-Moriguchi, K, Sun, Z.-Y.J, Prasad, B.V.V, Taniguchi, K, Dormitzer, P.R. | | Deposit date: | 2005-07-22 | | Release date: | 2006-02-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.604 Å) | | Cite: | High-resolution molecular and antigen structure of the VP8*
core of a sialic acid-independent human rotavirus strain
J.Virol., 80, 2006
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2C86
 | | x-ray structure of the N and C-terminal domain of coronavirus nucleocapsid protein. | | Descriptor: | NUCLEOCAPSID PROTEIN | | Authors: | Jayaram, H, Fan, H, Bowman, B.R, Ooi, A, Jayaram, J, Collinson, E.W, Lescar, J, Prasad, B.V.V. | | Deposit date: | 2005-12-02 | | Release date: | 2006-06-21 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | X-Ray Structures of the N- and C-Terminal Domains of a Coronavirus Nucleocapsid Protein: Implications for Nucleocapsid Formation.
J.Virol., 80, 2006
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2CA1
 | | Crystal structure of the IBV coronavirus nucleocapsid | | Descriptor: | NUCLEOCAPSID PROTEIN | | Authors: | Jayaram, H, Fan, H, Bowman, B.R, Ooi, A, Jayaram, J, Collison, E.W, Lescar, J, Prasad, B.V.V. | | Deposit date: | 2005-12-16 | | Release date: | 2006-06-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | X-Ray Structures of the N- and C-Terminal Domains of a Coronavirus Nucleocapsid Protein: Implications for Nucleocapsid Formation.
J.Virol., 80, 2006
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7S5S
 | | CTX-M-15 WT in complex with BLIP WT | | Descriptor: | Beta-lactamase, Beta-lactamase inhibitory protein | | Authors: | Lu, S, Palzkill, T, Hu, L.Y, Prasad, B.V.V, Sankaran, B. | | Deposit date: | 2021-09-11 | | Release date: | 2022-11-30 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | An active site loop toggles between conformations to control antibiotic hydrolysis and inhibition potency for CTX-M beta-lactamase drug-resistance enzymes.
Nat Commun, 13, 2022
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2R7J
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2R7P
 | | Crystal Structure of H225A NSP2 and AMPPNP complex | | Descriptor: | Non-structural RNA-binding protein 35, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Kumar, M, Prasad, B.V.V. | | Deposit date: | 2007-09-09 | | Release date: | 2007-10-23 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystallographic and Biochemical Analysis of Rotavirus NSP2 with Nucleotides Reveals a Nucleoside Diphosphate Kinase-Like Activity
J.Virol., 81, 2007
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2R7C
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2R8F
 | | Crystal structure of H225A NSP2 and ATP-gS complex | | Descriptor: | Non-structural RNA-binding protein 35, PHOSPHATE ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | Authors: | Kumar, M, Prasad, B.V.V. | | Deposit date: | 2007-09-10 | | Release date: | 2007-10-23 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystallographic and Biochemical Analysis of Rotavirus NSP2 with Nucleotides Reveals a Nucleoside Diphosphate Kinase-Like Activity
J.Virol., 81, 2007
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