7S5S
CTX-M-15 WT in complex with BLIP WT
Summary for 7S5S
| Entry DOI | 10.2210/pdb7s5s/pdb |
| Descriptor | Beta-lactamase, Beta-lactamase inhibitory protein (3 entities in total) |
| Functional Keywords | beta-lactamase, antibiotic resistance, beta-lactamase inhibitory protein, protein complex, protein binding |
| Biological source | Escherichia coli More |
| Total number of polymer chains | 2 |
| Total formula weight | 45567.19 |
| Authors | Lu, S.,Palzkill, T.,Hu, L.Y.,Prasad, B.V.V.,Sankaran, B. (deposition date: 2021-09-11, release date: 2022-11-30, Last modification date: 2023-10-25) |
| Primary citation | Lu, S.,Hu, L.,Lin, H.,Judge, A.,Rivera, P.,Palaniappan, M.,Sankaran, B.,Wang, J.,Prasad, B.V.V.,Palzkill, T. An active site loop toggles between conformations to control antibiotic hydrolysis and inhibition potency for CTX-M beta-lactamase drug-resistance enzymes. Nat Commun, 13:6726-6726, 2022 Cited by PubMed: 36344533DOI: 10.1038/s41467-022-34564-3 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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