7R6Z

OXA-48 bound by Compound 3.3

Summary for 7R6Z

Entry DOI	10.2210/pdb7r6z/pdb
Descriptor	Beta-lactamase, 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid, 1,2-ETHANEDIOL, ... (6 entities in total)
Functional Keywords	beta-lactamase, carbapenemase, beta-lactamase inhibitor, complex, oxacillinase, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor
Biological source	Klebsiella pneumoniae
Total number of polymer chains	2
Total formula weight	57704.17
Authors	Taylor, D.M.,Hu, L.,Prasad, B.V.V.,Sankaran, B.,Palzkill, T. (deposition date: 2021-06-24, release date: 2021-12-01, Last modification date: 2023-11-15)
Primary citation	Taylor, D.M.,Anglin, J.,Hu, L.,Wang, L.,Sankaran, B.,Wang, J.,Matzuk, M.M.,Prasad, B.V.V.,Palzkill, T. Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of Escherichia coli Producing OXA-48. Acs Infect Dis., 7:3345-3354, 2021 Cited by PubMed: 34817169 DOI: 10.1021/acsinfecdis.1c00501 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation