4EC2
Crystal structure of trimeric frataxin from the yeast Saccharomyces cerevisiae, complexed with ferrous
Summary for 4EC2
Entry DOI | 10.2210/pdb4ec2/pdb |
Related | 2FQL 3OEQ 3OER |
Descriptor | Frataxin homolog, mitochondrial, FE (II) ION (2 entities in total) |
Functional Keywords | alpha/beta sandwich, metallochaperone, iron-storage, transport protein |
Biological source | Saccharomyces cerevisiae (Baker's yeast) |
Cellular location | Mitochondrion matrix : Q07540 |
Total number of polymer chains | 1 |
Total formula weight | 13727.03 |
Authors | Soderberg, C.A.G.,Rajan, S.,Gakh, O.,Isaya, G.,Al-Karadaghi, S. (deposition date: 2012-03-26, release date: 2013-01-30, Last modification date: 2023-09-13) |
Primary citation | Soderberg, C.A.,Rajan, S.,Shkumatov, A.V.,Gakh, O.,Schaefer, S.,Ahlgren, E.C.,Svergun, D.I.,Isaya, G.,Al-Karadaghi, S. The molecular basis of iron-induced oligomerization of frataxin and the role of the ferroxidation reaction in oligomerization. J.Biol.Chem., 288:8156-8167, 2013 Cited by PubMed: 23344952DOI: 10.1074/jbc.M112.442285 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.002 Å) |
Structure validation
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