2DKJ
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![BU of 2dkj by Molmil](/molmil-images/mine/2dkj) | Crystal Structure of T.th.HB8 Serine Hydroxymethyltransferase | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, SULFATE ION, serine hydroxymethyltransferase | 著者 | Kai, K, Goto, M, Miyahara, I, Hirotsu, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-04-11 | 公開日 | 2007-04-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Crystal Structure of T.th.HB8 Serine Hydroxymethyltransferase To be Published
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4K0W
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![BU of 4k0w by Molmil](/molmil-images/mine/4k0w) | X-ray crystal structure of OXA-23 A220 duplication clinical variant | 分子名称: | 1,2-ETHANEDIOL, BICARBONATE ION, Beta-lactamase, ... | 著者 | Kaitany, K.J, Klinger, N.V, Leonard, D.A, Powers, R.A. | 登録日 | 2013-04-04 | 公開日 | 2013-08-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structures of the Class D Carbapenemases OXA-23 and OXA-146: Mechanistic Basis of Activity against Carbapenems, Extended-Spectrum Cephalosporins, and Aztreonam. Antimicrob.Agents Chemother., 57, 2013
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7E7F
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![BU of 7e7f by Molmil](/molmil-images/mine/7e7f) | Human CYP11B1 mutant in complex with metyrapone | 分子名称: | CHOLIC ACID, Cytochrome P450 11B1, mitochondrial, ... | 著者 | Mukai, K, Sugimoto, H, Reiko, S, Matsuura, T, Hishiki, T, Kagawa, N. | 登録日 | 2021-02-26 | 公開日 | 2022-01-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Spatially restricted substrate-binding site of cortisol-synthesizing CYP11B1 limits multiple hydroxylations and hinders aldosterone synthesis. Curr Res Struct Biol, 3, 2021
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2VQF
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![BU of 2vqf by Molmil](/molmil-images/mine/2vqf) | Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U-G wobble pairing during decoding | 分子名称: | 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | 著者 | Kurata, S, Weixlbaumer, A, Ohtsuki, T, Shimazaki, T, Wada, T, Kirino, Y, Takai, K, Watanabe, K, Ramakrishnan, V, Suzuki, T. | 登録日 | 2008-03-14 | 公開日 | 2008-04-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Modified Uridines with C5-Methylene Substituents at the First Position of the tRNA Anticodon Stabilize U.G Wobble Pairing During Decoding. J.Biol.Chem., 283, 2008
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7DCZ
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![BU of 7dcz by Molmil](/molmil-images/mine/7dcz) | Crystal Structure of BACE1 in complex with N-{3-[(4S)-2-amino-4-methyl-4H-1,3-thiazin-4-yl]-4- fluorophenyl}-5-cyanopyridine-2-carboxamide | 分子名称: | Beta-secretase 1, GLYCEROL, IODIDE ION, ... | 著者 | Koriyama, Y, Hori, A, Ito, H, Yonezawa, S, Baba, Y, Tanimoto, N, Ueno, T, Yamamoto, S, Yamamoto, T, Asada, N, Morimoto, K, Einaru, S, Sakai, K, Kanazu, T, Matsuda, A, Yamaguchi, Y, Oguma, T, Timmers, M, Tritsmans, L, Kusakabe, K.I, Kato, A, Sakaguchi, G. | 登録日 | 2020-10-27 | 公開日 | 2021-03-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovery of Atabecestat (JNJ-54861911): A Thiazine-Based beta-Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor Advanced to the Phase 2b/3 EARLY Clinical Trial. J.Med.Chem., 64, 2021
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2VQE
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![BU of 2vqe by Molmil](/molmil-images/mine/2vqe) | Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U-G wobble pairing during decoding | 分子名称: | 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | 著者 | Kurata, S, Weixlbaumer, A, Ohtsuki, T, Shimazaki, T, Wada, T, Kirino, Y, Takai, K, Watanabe, K, Ramakrishnan, V, Suzuki, T. | 登録日 | 2008-03-13 | 公開日 | 2008-04-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Modified Uridines with C5-Methylene Substituents at the First Position of the tRNA Anticodon Stabilize U.G Wobble Pairing During Decoding. J.Biol.Chem., 283, 2008
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5GUA
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![BU of 5gua by Molmil](/molmil-images/mine/5gua) | Structure of biotin carboxyl carrier protein from pyrococcus horikoshi OT3 (delta N79) A138Y mutant | 分子名称: | 149aa long hypothetical methylmalonyl-CoA decarboxylase gamma chain | 著者 | Yamada, K, Kunishima, N, Matsuura, Y, Nakai, K, Naitow, H, Fukasawa, Y, Tomii, K. | 登録日 | 2016-08-26 | 公開日 | 2017-08-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Designing better diffracting crystals of biotin carboxyl carrier protein from Pyrococcus horikoshii by a mutation based on the crystal-packing propensity of amino acids. Acta Crystallogr D Struct Biol, 73, 2017
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5GU9
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![BU of 5gu9 by Molmil](/molmil-images/mine/5gu9) | Structure of biotin carboxyl carrier protein from pyrococcus horikoshi OT3 (delta N79) A138I mutant | 分子名称: | 149aa long hypothetical methylmalonyl-CoA decarboxylase gamma chain | 著者 | Yamada, K, Kunishima, N, Matsuura, Y, Nakai, K, Naitow, H, Fukasawa, Y, Tomii, K. | 登録日 | 2016-08-26 | 公開日 | 2017-08-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Designing better diffracting crystals of biotin carboxyl carrier protein from Pyrococcus horikoshii by a mutation based on the crystal-packing propensity of amino acids. Acta Crystallogr D Struct Biol, 73, 2017
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5GU8
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![BU of 5gu8 by Molmil](/molmil-images/mine/5gu8) | Structure of biotin carboxyl carrier protein from pyrococcus horikoshi OT3 (delta N79) wild type | 分子名称: | 149aa long hypothetical methylmalonyl-CoA decarboxylase gamma chain, SODIUM ION | 著者 | Yamada, K, Kunishima, N, Matsuura, Y, Nakai, K, Naitow, H, Fukasawa, Y, Tomii, K. | 登録日 | 2016-08-26 | 公開日 | 2017-08-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Designing better diffracting crystals of biotin carboxyl carrier protein from Pyrococcus horikoshii by a mutation based on the crystal-packing propensity of amino acids. Acta Crystallogr D Struct Biol, 73, 2017
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7WAG
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![BU of 7wag by Molmil](/molmil-images/mine/7wag) | Crystal structure of MurJ squeezed form | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Lipid II flippase MurJ | 著者 | Tsukazaki, T, Kohga, H, Tanaka, Y, Yoshikaie, K, Taniguchi, K, Fujimoto, K. | 登録日 | 2021-12-14 | 公開日 | 2022-06-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Crystal structure of the lipid flippase MurJ in a "squeezed" form distinct from its inward- and outward-facing forms. Structure, 30, 2022
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7WAW
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![BU of 7waw by Molmil](/molmil-images/mine/7waw) | MurJ inward closed form | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, lipid II flippase MurJ | 著者 | Tsukazaki, T, Kohga, H, Tanaka, Y, Yoshikaie, K, Taniguchi, K, Fujimoto, K. | 登録日 | 2021-12-15 | 公開日 | 2022-06-01 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of the lipid flippase MurJ in a "squeezed" form distinct from its inward- and outward-facing forms. Structure, 30, 2022
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7WAX
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![BU of 7wax by Molmil](/molmil-images/mine/7wax) | MurJ inward occluded form | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (4S)-2-METHYL-2,4-PENTANEDIOL, lipid II flippase MurJ | 著者 | Tsukazaki, T, Kohga, H, Tanaka, Y, Yoshikaie, K, Taniguchi, K, Fujimoto, K. | 登録日 | 2021-12-15 | 公開日 | 2022-06-01 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal structure of the lipid flippase MurJ in a "squeezed" form distinct from its inward- and outward-facing forms. Structure, 30, 2022
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6LEO
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![BU of 6leo by Molmil](/molmil-images/mine/6leo) | Crystal structure of thiosulfate transporter YeeE from Spirochaeta thermophila | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Sulf_transp domain-containing protein, THIOSULFATE | 著者 | Tanaka, Y, Tsukazaki, T, Yoshikaie, K, Takeuchi, A, Uchino, S, Sugano, Y. | 登録日 | 2019-11-26 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-30 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Crystal structure of a YeeE/YedE family protein engaged in thiosulfate uptake. Sci Adv, 6, 2020
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6LEP
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![BU of 6lep by Molmil](/molmil-images/mine/6lep) | Crystal structure of thiosulfate transporter YeeE inactive mutant - C91A | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Sulf_transp domain-containing protein, THIOSULFATE | 著者 | Tanaka, Y, Tsukazaki, T, Yoshikaie, K, Sugano, Y, Takeuchi, A, Uchino, S. | 登録日 | 2019-11-26 | 公開日 | 2020-09-02 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of a YeeE/YedE family protein engaged in thiosulfate uptake. Sci Adv, 6, 2020
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1UIX
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![BU of 1uix by Molmil](/molmil-images/mine/1uix) | Coiled-coil structure of the RhoA-binding domain in Rho-kinase | 分子名称: | Rho-associated kinase | 著者 | Shimizu, T, Ihara, K, Maesaki, R, Amano, M, Kaibuchi, K, Hakoshima, T. | 登録日 | 2003-07-23 | 公開日 | 2003-10-21 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Parallel coiled-coil association of the RhoA-binding domain in Rho-kinase J.Biol.Chem., 278, 2003
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2H9V
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![BU of 2h9v by Molmil](/molmil-images/mine/2h9v) | Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y27632 | 分子名称: | (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE, Rho-associated protein kinase 2 | 著者 | Yamaguchi, H, Miwa, Y, Kasa, M, Kitano, K, Amano, M, Kaibuchi, K, Hakoshima, T. | 登録日 | 2006-06-12 | 公開日 | 2006-12-05 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y-27632 J.Biochem.(Tokyo), 140, 2006
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1CXZ
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![BU of 1cxz by Molmil](/molmil-images/mine/1cxz) | CRYSTAL STRUCTURE OF HUMAN RHOA COMPLEXED WITH THE EFFECTOR DOMAIN OF THE PROTEIN KINASE PKN/PRK1 | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, PROTEIN (HIS-TAGGED TRANSFORMING PROTEIN RHOA(0-181)), ... | 著者 | Maesaki, R, Ihara, K, Shimizu, T, Kuroda, S, Kaibuchi, K, Hakoshima, T. | 登録日 | 1999-08-31 | 公開日 | 1999-10-08 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1. Mol.Cell, 4, 1999
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1A2B
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![BU of 1a2b by Molmil](/molmil-images/mine/1a2b) | HUMAN RHOA COMPLEXED WITH GTP ANALOGUE | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN RHOA | 著者 | Ihara, K, Muraguchi, S, Kato, M, Shimizu, T, Shirakawa, M, Kuroda, S, Kaibuchi, K, Hakoshima, T. | 登録日 | 1997-12-26 | 公開日 | 1998-06-17 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue. J.Biol.Chem., 273, 1998
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4X6X
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![BU of 4x6x by Molmil](/molmil-images/mine/4x6x) | Human soluble epoxide hydrolase in complex with a three substituted cyclopropane derivative | 分子名称: | 3-{4-[(1-{[(1s,2R,3S)-2,3-diphenylcyclopropyl]carbamoyl}piperidin-4-yl)oxy]phenyl}propanoic acid, Bifunctional epoxide hydrolase 2 | 著者 | Chiyo, N, Takai, K, Ishii, T. | 登録日 | 2014-12-09 | 公開日 | 2015-04-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Three-dimensional rational approach to the discovery of potent substituted cyclopropyl urea soluble epoxide hydrolase inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
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4X6Y
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1DPF
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![BU of 1dpf by Molmil](/molmil-images/mine/1dpf) | CRYSTAL STRUCTURE OF A MG-FREE FORM OF RHOA COMPLEXED WITH GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, RHOA | 著者 | Shimizu, T, Ihara, K, Maesaki, R, Kuroda, S, Kaibuchi, K, Hakoshima, T. | 登録日 | 1999-12-27 | 公開日 | 2000-06-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | An open conformation of switch I revealed by the crystal structure of a Mg2+-free form of RHOA complexed with GDP. Implications for the GDP/GTP exchange mechanism. J.Biol.Chem., 275, 2000
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3A8Q
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![BU of 3a8q by Molmil](/molmil-images/mine/3a8q) | Low-resolution crystal structure of the Tiam2 PHCCEx domain | 分子名称: | T-lymphoma invasion and metastasis-inducing protein 2 | 著者 | Terawaki, S, Kitano, K, Mori, T, Zhai, Y, Higuchi, Y, Itoh, N, Watanabe, T, Kaibuchi, K, Hakoshima, T. | 登録日 | 2009-10-07 | 公開日 | 2009-11-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module Embo J., 29, 2010
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5YHF
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![BU of 5yhf by Molmil](/molmil-images/mine/5yhf) | Crystal structure of SecDF in Super-membrane-facing form | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Protein translocase subunit SecDF | 著者 | Tanaka, Y, Tsukazaki, T, Yoshikaie, K, Furukawa, A. | 登録日 | 2017-09-28 | 公開日 | 2018-02-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Remote Coupled Drastic beta-Barrel to beta-Sheet Transition of the Protein Translocation Motor. Structure, 26, 2018
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5YVQ
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![BU of 5yvq by Molmil](/molmil-images/mine/5yvq) | Complex of Mu phage tail fiber and its chaperone | 分子名称: | GLYCEROL, Tail fiber assembly protein U, Tail fiber protein S | 著者 | Takeda, S, Sakai, K, Iwazaki, T, Yamashita, E, Nakagawa, A. | 登録日 | 2017-11-27 | 公開日 | 2019-05-22 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | 主引用文献 | Phage tail fibre assembly proteins employ a modular structure to drive the correct folding of diverse fibres. Nat Microbiol, 4, 2019
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3A8P
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![BU of 3a8p by Molmil](/molmil-images/mine/3a8p) | Crystal structure of the Tiam2 PHCCEx domain | 分子名称: | T-lymphoma invasion and metastasis-inducing protein 2 | 著者 | Terawaki, S, Kitano, K, Mori, T, Zhai, Y, Higuchi, Y, Itoh, N, Watanabe, T, Kaibuchi, K, Hakoshima, T. | 登録日 | 2009-10-07 | 公開日 | 2009-11-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module Embo J., 29, 2010
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