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PDB: 1 results

7E7F
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Human CYP11B1 mutant in complex with metyrapone
Descriptor: CHOLIC ACID, Cytochrome P450 11B1, mitochondrial, ...
Authors:Mukai, K, Sugimoto, H, Reiko, S, Matsuura, T, Hishiki, T, Kagawa, N.
Deposit date:2021-02-26
Release date:2022-01-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Spatially restricted substrate-binding site of cortisol-synthesizing CYP11B1 limits multiple hydroxylations and hinders aldosterone synthesis.
Curr Res Struct Biol, 3, 2021

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