1CXZ

CRYSTAL STRUCTURE OF HUMAN RHOA COMPLEXED WITH THE EFFECTOR DOMAIN OF THE PROTEIN KINASE PKN/PRK1

Summary for 1CXZ

Related1A2B
DescriptorPROTEIN (HIS-TAGGED TRANSFORMING PROTEIN RHOA(0-181)), PROTEIN (PKN), MAGNESIUM ION, ... (5 entities in total)
Functional Keywordsprotein-protein complex, antiparallel coiled-coil, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Lipid-anchor; Cytoplasmic side P61586
Cytoplasm  Q16512
Total number of polymer chains2
Total molecular weight30971.42
Authors
Maesaki, R.,Ihara, K.,Shimizu, T.,Kuroda, S.,Kaibuchi, K.,Hakoshima, T. (deposition date: 1999-08-31, release date: 1999-10-08, Last modification date: 2018-03-14)
Primary citation
Maesaki, R.,Ihara, K.,Shimizu, T.,Kuroda, S.,Kaibuchi, K.,Hakoshima, T.
The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1.
Mol.Cell, 4:793-803, 1999
PubMed: 10619026 (PDB entries with the same primary citation)
DOI: 10.1016/S1097-2765(00)80389-5
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.26830.4%4.8%2.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload