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PDB: 502 results

7MHY
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BU of 7mhy by Molmil
Human Hedgehog acyltransferase (HHAT) in complex with palmitoyl-CoA and two Fab antibody fragments
Descriptor: 1C06 Fab heavy chain, 1C06 Fab light chain, 3H02 Fab heavy chain, ...
Authors:Long, S.B, Jiang, Y.
Deposit date:2021-04-16
Release date:2021-06-16
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Substrate and product complexes reveal mechanisms of Hedgehog acylation by HHAT.
Science, 372, 2021
7SAQ
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BU of 7saq by Molmil
Cryo-EM structure of TMEM106B fibrils extracted from a FTLD-TDP patient, polymorph 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
Authors:Cao, Q, Jiang, Y, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2021-09-23
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43.
Nature, 605, 2022
7SAR
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BU of 7sar by Molmil
Cryo-EM structure of TMEM106B fibrils extracted from a FTLD-TDP patient, polymorph 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
Authors:Cao, Q, Jiang, Y, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2021-09-23
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43.
Nature, 605, 2022
7RH9
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BU of 7rh9 by Molmil
Cryo-EM structure of human rod CNGA1/B1 channel in apo state
Descriptor: Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1
Authors:Xue, J, Han, Y, Jiang, Y.
Deposit date:2021-07-16
Release date:2021-11-03
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
Neuron, 110, 2022
7SAS
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BU of 7sas by Molmil
Cryo-EM structure of TMEM106B fibrils extracted from a FTLD-TDP patient, polymorph 3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
Authors:Cao, Q, Jiang, Y, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2021-09-23
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43.
Nature, 605, 2022
8F7S
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BU of 8f7s by Molmil
Gi bound delta-opioid receptor in complex with deltorphin
Descriptor: CHOLESTEROL, Delta-type opioid receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E.
Deposit date:2022-11-20
Release date:2022-12-14
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structures of the entire human opioid receptor family.
Cell, 186, 2023
8F7W
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BU of 8f7w by Molmil
Gi bound kappa-opioid receptor in complex with dynorphin
Descriptor: CHOLESTEROL, Dynorphin, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E.
Deposit date:2022-11-20
Release date:2022-12-14
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structures of the entire human opioid receptor family.
Cell, 186, 2023
8F7Q
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BU of 8f7q by Molmil
Gi bound mu-opioid receptor in complex with beta-endorphin
Descriptor: Beta-endorphin, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E.
Deposit date:2022-11-20
Release date:2022-12-14
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Structures of the entire human opioid receptor family.
Cell, 186, 2023
8F7R
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BU of 8f7r by Molmil
Gi bound mu-opioid receptor in complex with endomorphin
Descriptor: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E.
Deposit date:2022-11-20
Release date:2022-12-14
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structures of the entire human opioid receptor family.
Cell, 186, 2023
8F7X
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BU of 8f7x by Molmil
Gi bound nociceptin receptor in complex with nociceptin peptide
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Wang, Y, Zhuang, Y, DiBerto, J.F, Zhou, X.E, Schmitz, G.P, Yuan, Q, Jain, M.K, Liu, W, Melcher, K, Jiang, Y, Roth, B.L, Xu, H.E.
Deposit date:2022-11-20
Release date:2022-12-14
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structures of the entire human opioid receptor family.
Cell, 186, 2023
3R65
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BU of 3r65 by Molmil
MthK channel pore E92Q mutant
Descriptor: Calcium-gated potassium channel mthK, POTASSIUM ION
Authors:Shi, N, Zeng, W, Ye, S, Li, Y, Jiang, Y.
Deposit date:2011-03-21
Release date:2012-02-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crucial points within the pore as determinants of K+ channel conductance and gating
J.Mol.Biol., 411, 2011
7MHZ
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BU of 7mhz by Molmil
Human Hedgehog acyltransferase (HHAT) in complex with a palmitoylated Hedgehog peptide product and a Fab antibody fragment
Descriptor: 3H02 Fab heavy chain, 3H02 Fab light chain, Digitonin, ...
Authors:Long, S.B, Jiang, Y.
Deposit date:2021-04-16
Release date:2021-06-16
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Substrate and product complexes reveal mechanisms of Hedgehog acylation by HHAT.
Science, 372, 2021
7JVR
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BU of 7jvr by Molmil
Cryo-EM structure of Bromocriptine-bound dopamine receptor 2 in complex with Gi protein
Descriptor: Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E.
Deposit date:2020-08-22
Release date:2021-02-24
Last modified:2021-03-31
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
7JVQ
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BU of 7jvq by Molmil
Cryo-EM structure of apomorphine-bound dopamine receptor 1 in complex with Gs protein
Descriptor: (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol, CHOLESTEROL, D(1A) dopamine receptor, ...
Authors:Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E.
Deposit date:2020-08-22
Release date:2021-02-24
Last modified:2021-03-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
7JVP
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BU of 7jvp by Molmil
Cryo-EM structure of SKF-83959-bound dopamine receptor 1 in complex with Gs protein
Descriptor: (1R)-6-chloro-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, CHOLESTEROL, D(1A) dopamine receptor, ...
Authors:Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E.
Deposit date:2020-08-22
Release date:2021-02-24
Last modified:2021-03-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
7JV5
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BU of 7jv5 by Molmil
Cryo-EM structure of SKF-81297-bound dopamine receptor 1 in complex with Gs protein
Descriptor: (1R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, CHOLESTEROL, D(1A) dopamine receptor, ...
Authors:Zhuang, Y, Xu, P, Mao, C, Wang, L, Krumm, B, Zhou, X.E, Huang, S, Liu, H, Cheng, X, Huang, X.-P, Sheng, D.-D, Xu, T, Liu, Y.-F, Wang, Y, Guo, J, Jiang, Y, Jiang, H, Melcher, K, Roth, B.L, Zhang, Y, Zhang, C, Xu, H.E.
Deposit date:2020-08-20
Release date:2021-02-24
Last modified:2021-03-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
Cell, 184, 2021
5TUA
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BU of 5tua by Molmil
structure of a Na+-selective mutant of two-pore channel from Arabidopsis thaliana AtTPC1
Descriptor: BARIUM ION, CALCIUM ION, SODIUM ION, ...
Authors:Guo, J, Zeng, W, Jiang, Y.
Deposit date:2016-11-05
Release date:2017-01-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Tuning the ion selectivity of two-pore channels.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3T4Z
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BU of 3t4z by Molmil
Crystal Structure of NaK2K Channel Y55W Mutant
Descriptor: POTASSIUM ION, Potassium channel protein
Authors:Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y.
Deposit date:2011-07-26
Release date:2011-10-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation.
Proc.Natl.Acad.Sci.USA, 108, 2011
3T4D
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BU of 3t4d by Molmil
Crystal Structure of NaK2K Channel Y55F Mutant
Descriptor: POTASSIUM ION, Potassium channel protein
Authors:Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y.
Deposit date:2011-07-25
Release date:2011-10-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation.
Proc.Natl.Acad.Sci.USA, 108, 2011
3TCU
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BU of 3tcu by Molmil
Crystal Structure of NaK2K Channel D68E Mutant
Descriptor: POTASSIUM ION, Potassium channel protein
Authors:Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y.
Deposit date:2011-08-09
Release date:2011-10-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation.
Proc.Natl.Acad.Sci.USA, 108, 2011
3OUF
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BU of 3ouf by Molmil
Structure of a K+ selective NaK mutant
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein
Authors:Derebe, M.G, Sauer, D.B, Zeng, W, Alam, A, Shi, N, Jiang, Y.
Deposit date:2010-09-14
Release date:2011-01-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites.
Proc.Natl.Acad.Sci.USA, 108, 2011
3OUS
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BU of 3ous by Molmil
MthK channel pore T59A mutant
Descriptor: Calcium-gated potassium channel mthK, POTASSIUM ION
Authors:Derebe, M.G, Sauer, D.B, Zeng, W, Alam, A, Shi, N, Jiang, Y.
Deposit date:2010-09-15
Release date:2011-01-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites.
Proc.Natl.Acad.Sci.USA, 108, 2011
3T2M
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BU of 3t2m by Molmil
Crystal Structure of NaK Channel N68D Mutant
Descriptor: POTASSIUM ION, Potassium channel protein
Authors:Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y.
Deposit date:2011-07-22
Release date:2011-10-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.953 Å)
Cite:Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation.
Proc.Natl.Acad.Sci.USA, 108, 2011
3T1C
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BU of 3t1c by Molmil
Crystal Structure of NaK Channel D66Y Mutant
Descriptor: POTASSIUM ION, Potassium channel protein
Authors:Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y.
Deposit date:2011-07-21
Release date:2011-10-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation.
Proc.Natl.Acad.Sci.USA, 108, 2011
3TET
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BU of 3tet by Molmil
Crystal Structure of NaK2K Channel Y66F Mutant
Descriptor: POTASSIUM ION, Potassium channel protein
Authors:Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y.
Deposit date:2011-08-15
Release date:2011-10-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation.
Proc.Natl.Acad.Sci.USA, 108, 2011

221716

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