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PDB: 98 件

4G9Z
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Lassa nucleoprotein with dsRNA reveals novel mechanism for immune suppression
分子名称: Nucleoprotein, RNA (5'-R(P*GP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*C)-3'), ...
著者Jiang, X, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C, Scottish Structural Proteomics Facility (SSPF)
登録日2012-07-24
公開日2013-04-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4GVE
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Tacaribe nucleoprotein structure
分子名称: MAGNESIUM ION, Nucleoprotein, ZINC ION
著者Jiang, X, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C.
登録日2012-08-30
公開日2013-05-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4GV6
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Structures of Lassa and Tacaribe viral nucleoproteins with or without 5 triphosphate dsRNA substrate reveal a unique 3 -5 exoribonuclease mechanism to suppress type I interferon production
分子名称: MANGANESE (II) ION, Nucleoprotein, RNA (5'-R(*(GTP)P*GP*GP*C)-3'), ...
著者Jiang, X, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C.
登録日2012-08-30
公開日2013-05-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4GV9
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Lassa nucleoprotein C-terminal domain in complex with triphosphated dsRNA soaking for 5 min
分子名称: MANGANESE (II) ION, Nucleoprotein, RNA (5'-R(*(GTP)P*GP*GP*C)-3'), ...
著者Jiang, X, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C.
登録日2012-08-30
公開日2013-05-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4GV3
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Structures of Lassa and Tacaribe viral nucleoproteins with or without 5 triphosphate dsRNA substrate reveal a unique 3 -5 exoribonuclease mechanism to suppress type I interferon production
分子名称: MANGANESE (II) ION, Nucleoprotein, RNA (5'-R(*(GTP)P*GP*GP*C)-3'), ...
著者Jiang, X, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C.
登録日2012-08-30
公開日2013-05-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
1GKO
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An Engineered Transthyretin Monomer that is Non-amyloidogenic - Unless Partially Denatured
分子名称: TRANSTHYRETIN
著者Jiang, X, Smith, C.S, Petrassi, H.M, Hammarstrom, P, White, J.T, Sacchettini, J.C, Kelly, J.W.
登録日2001-08-17
公開日2001-11-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献An Engineered Transthyretin Monomer that is Nonamyloidogenic, Unless It is Partially Denatured
Biochemistry, 40, 2001
1SCF
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HUMAN RECOMBINANT STEM CELL FACTOR
分子名称: CALCIUM ION, PENTAETHYLENE GLYCOL, STEM CELL FACTOR
著者Jiang, X, Gurel, O, Langley, K.E, Hendrickson, W.A.
登録日1998-06-04
公開日2000-07-07
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the active core of human stem cell factor and analysis of binding to its receptor kit.
EMBO J., 19, 2000
4AY9
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Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLLICLE-STIMULATING HORMONE RECEPTOR, FOLLITROPIN SUBUNIT BETA, ...
著者Jiang, X, Liu, H, Chen, X, He, X.
登録日2012-06-19
公開日2012-08-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Follicle-Stimulating Hormone in Complex with the Entire Ectodomain of its Receptor.
Proc.Natl.Acad.Sci.USA, 109, 2012
3WZF
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Crystal structure of human cytoplasmic aspartate aminotransferase
分子名称: Aspartate aminotransferase, cytoplasmic
著者Jiang, X, Chang, H, Zhou, Y, Chen, L, Yang, Q.
登録日2014-09-24
公開日2015-10-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.991 Å)
主引用文献Recombinant expression, purification and Preliminary crystallographic studies of human cytoplasmic aspartate aminotransferase
To be Published
5AX8
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Recombinant expression, purification and preliminary crystallographic studies of the mature form of human mitochondrial aspartate aminotransferase
分子名称: Aspartate aminotransferase, mitochondrial
著者Jiang, X, Wang, J, Chang, H, Zhou, Y.
登録日2015-07-20
公開日2016-03-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.989 Å)
主引用文献Recombinant expression, purification and crystallographic studies of the mature form of human mitochondrial aspartate aminotransferase
Biosci Trends, 10, 2016
2GU0
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Crystal Structure of Human Rotavirus NSP2 (Group C / Bristol Strain)
分子名称: Nonstructural protein 2
著者Jiang, X, Prasad, B.V.V.
登録日2006-04-28
公開日2006-09-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-function analysis of rotavirus NSP2 octamer by using a novel complementation system
J.Virol., 80, 2006
6DI1
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CRYSTAL STRUCTURE OF BTK IN COMPLEX WITH COVALENT FRAGMENT LIGAND
分子名称: 4-amino-2-[(3S)-3-(propanoylamino)pyrrolidin-1-yl]pyrimidine-5-carboxamide, Tyrosine-protein kinase BTK
著者Jiang, X.
登録日2018-05-22
公開日2018-10-17
最終更新日2018-10-24
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Discovery of a novel series of pyridine and pyrimidine carboxamides as potent and selective covalent inhibitors of Btk.
Bioorg. Med. Chem. Lett., 28, 2018
6JIR
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Crystal structure of C. crescentus beta sliding clamp with PEG bound to putative beta-motif tethering region
分子名称: 1,2-ETHANEDIOL, Beta sliding clamp, DI(HYDROXYETHYL)ETHER, ...
著者Jiang, X, Teng, M, Li, X.
登録日2019-02-23
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Caulobacter crescentus beta sliding clamp employs a noncanonical regulatory model of DNA replication.
Febs J., 287, 2020
6IZO
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Crystal structure of DNA polymerase sliding clamp from Caulobacter crescentus
分子名称: 1,2-ETHANEDIOL, Beta sliding clamp, DI(HYDROXYETHYL)ETHER
著者Jiang, X, Zhang, L, Teng, M, Li, X.
登録日2018-12-20
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Caulobacter crescentus beta sliding clamp employs a noncanonical regulatory model of DNA replication.
Febs J., 287, 2020
4JAJ
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Crystal Structure of Aurora Kinase A in complex with BENZO[C][1,8]NAPHTHYRIDIN-6(5H)-ONE
分子名称: Aurora kinase A, benzo[c][1,8]naphthyridin-6(5H)-one
著者Jiang, X, Josephson, K, Huck, B, Goutopoulos, A, Karra, S.
登録日2013-02-18
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
4JAI
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Crystal Structure of Aurora Kinase A in complex with N-{4-[(6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridin-1-yl)amino]phenyl}benzamide
分子名称: Aurora kinase A, N-{4-[(6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridin-1-yl)amino]phenyl}benzamide
著者Jiang, X, Josephson, K, Huck, B, Goutopoulos, A, Karra, S.
登録日2013-02-18
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
6JK6
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Crystal structure of human chitotriosidase-1 (hCHIT) catalytic domain in complex with compound 2-8-s2
分子名称: 6-azanyl-11-methyl-2-oxidanylidene-7-[[(2R)-oxolan-2-yl]methyl]-N-(pyridin-3-ylmethyl)-1,9-diaza-7-azoniatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,6,9,11,13-hexaene-5-carboxamide, Chitotriosidase-1
著者Jiang, X, Yang, Q.
登録日2019-02-27
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.571 Å)
主引用文献A Series of Compounds Bearing a Dipyrido-Pyrimidine Scaffold Acting as Novel Human and Insect Pest Chitinase Inhibitors.
J.Med.Chem., 63, 2020
6JMN
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Crystal structure of Ostrinia furnacalis Chitinase h complexed with compound 2-8-s2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-azanyl-11-methyl-2-oxidanylidene-7-[[(2R)-oxolan-2-yl]methyl]-N-(pyridin-3-ylmethyl)-1,9-diaza-7-azoniatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,6,9,11,13-hexaene-5-carboxamide, Chitinase
著者Jiang, X, Yang, Q.
登録日2019-03-12
公開日2020-05-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Series of Compounds Bearing a Dipyrido-Pyrimidine Scaffold Acting as Novel Human and Insect Pest Chitinase Inhibitors.
J.Med.Chem., 63, 2020
6JJR
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Crystal structure of human chitotriosidase-1 (hChit1) catalytic domain in complex with compound 2-8-14
分子名称: 6-azanyl-2-oxidanylidene-N-[(1S)-1-phenylethyl]-7-(phenylmethyl)-1$l^{4},9-diaza-7-azoniatricyclo[8.4.0.0^{3,8}]tetradeca-1(14),3(8),4,6,10,12-hexaene-5-carboxamide, Chitotriosidase-1
著者Jiang, X, Yang, Q.
登録日2019-02-26
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.834 Å)
主引用文献A Series of Compounds Bearing a Dipyrido-Pyrimidine Scaffold Acting as Novel Human and Insect Pest Chitinase Inhibitors.
J.Med.Chem., 63, 2020
6JK9
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Crystal structure of Serratia marcescens Chitinase B complexed with compound 2-8-14
分子名称: 6-azanyl-2-oxidanylidene-N-[(1S)-1-phenylethyl]-7-(phenylmethyl)-1$l^{4},9-diaza-7-azoniatricyclo[8.4.0.0^{3,8}]tetradeca-1(14),3(8),4,6,10,12-hexaene-5-carboxamide, Chitinase
著者Jiang, X, Yang, Q.
登録日2019-02-27
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.312 Å)
主引用文献A Series of Compounds Bearing a Dipyrido-Pyrimidine Scaffold Acting as Novel Human and Insect Pest Chitinase Inhibitors.
J.Med.Chem., 63, 2020
5GXB
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crystal structure of a LacY/Nanobody complex
分子名称: Lactose permease, nanobody
著者Jiang, X, Wu, J.P, Yan, N, Kaback, H.R.
登録日2016-09-16
公開日2016-10-26
最終更新日2022-10-12
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation.
Proc.Natl.Acad.Sci.USA, 113, 2016
6M20
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Crystal structure of Plasmodium falciparum hexose transporter PfHT1 bound with glucose
分子名称: Hexose transporter 1, beta-D-glucopyranose, nonyl beta-D-glucopyranoside
著者Jiang, X, Yuan, Y.Y, Zhang, S, Wang, N, Yan, C.Y, Yan, N.
登録日2020-02-26
公開日2020-09-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum.
Cell, 183, 2020
4MQW
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Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor (P31)
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Follicle-stimulating hormone receptor, ...
著者Jiang, X, Liu, H, Chen, X, He, X.
登録日2013-09-16
公開日2014-04-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer.
J.Biol.Chem., 289, 2014
6M2L
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Crystal structure of Plasmodium falciparum hexose transporter PfHT1 bound with C3361
分子名称: (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol, Hexose transporter 1
著者Jiang, X, Yuan, Y.Y, Zhang, S, Wang, N, Yan, C.Y, Yan, N.
登録日2020-02-27
公開日2020-09-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum.
Cell, 183, 2020
6JVB
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Crystal Structure of Human CRMP2 1-532, AGE-modified
分子名称: Dihydropyrimidinase-related protein 2
著者Jiang, X, Ogawa, T, Hirokawa, N.
登録日2019-04-16
公開日2019-10-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Enhanced carbonyl stress induces irreversible multimerization of CRMP2 in schizophrenia pathogenesis.
Life Sci Alliance, 2, 2019

 

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