5AX8

Recombinant expression, purification and preliminary crystallographic studies of the mature form of human mitochondrial aspartate aminotransferase

Summary for 5AX8

Related3PDB
DescriptorAspartate aminotransferase, mitochondrial (1 entity in total)
Functional Keywordsaspartate aminotransferase, plasma membrane fatty acid binding protein, kynurenine aminotransferase-iv, three-dimensional structure, transferase
Biological sourceHomo sapiens (Human)
Cellular locationMitochondrion matrix  P00505
Total number of polymer chains4
Total molecular weight182332.34
Authors
Jiang, X.,Wang, J.,Chang, H.,Zhou, Y. (deposition date: 2015-07-20, release date: 2016-03-16, Last modification date: 2016-04-06)
Primary citation
Jiang, X.,Wang, J.,Chang, H.,Zhou, Y.
Recombinant expression, purification and crystallographic studies of the mature form of human mitochondrial aspartate aminotransferase
Biosci Trends, 10:79-84, 2016
PubMed: 26902786 (PDB entries with the same primary citation)
DOI: 10.5582/bst.2015.01150
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.989 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.290330.3%11.2%5.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution