4MQW

Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor (P31)

Summary for 4MQW

• Entry DOI: 10.2210/pdb4mqw/pdb
• Related: 4ay9
• Descriptor: Glycoprotein hormones, alpha polypeptide, Follitropin subunit beta, Follicle-stimulating hormone receptor, ... (7 entities in total)
• Functional Keywords: cystine-knot, leucine-rich repeats, glycoprotein hormone, gpcr, sulfation, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 9
• Total formula weight: 199817.15

Authors

Jiang, X.,Liu, H.,Chen, X.,He, X. (deposition date: 2013-09-16, release date: 2014-04-09, Last modification date: 2024-01-10)

• Primary citation: Jiang, X.,Fischer, D.,Chen, X.,McKenna, S.D.,Liu, H.,Sriraman, V.,Yu, H.N.,Goutopoulos, A.,Arkinstall, S.,He, X.; Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer.; J.Biol.Chem., 289:14273-14282, 2014; PubMed: 24692546; DOI: 10.1074/jbc.M114.549592

Experimental method

X-RAY DIFFRACTION (2.9 Å)