1SCF
HUMAN RECOMBINANT STEM CELL FACTOR
Summary for 1SCF
Entry DOI | 10.2210/pdb1scf/pdb |
Descriptor | STEM CELL FACTOR, PENTAETHYLENE GLYCOL, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | human stem cell factor, steel factor, kit ligand, mast cell growth factor, hormone-growth factor complex, hormone/growth factor |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein (By similarity). Soluble KIT ligand: Secreted: P21583 |
Total number of polymer chains | 4 |
Total formula weight | 124655.41 |
Authors | Jiang, X.,Gurel, O.,Langley, K.E.,Hendrickson, W.A. (deposition date: 1998-06-04, release date: 2000-07-07, Last modification date: 2022-12-21) |
Primary citation | Jiang, X.,Gurel, O.,Mendiaz, E.A.,Stearns, G.W.,Clogston, C.L.,Lu, H.S.,Osslund, T.D.,Syed, R.S.,Langley, K.E.,Hendrickson, W.A. Structure of the active core of human stem cell factor and analysis of binding to its receptor kit. EMBO J., 19:3192-3203, 2000 Cited by PubMed: 10880433DOI: 10.1093/emboj/19.13.3192 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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