6M2L

Crystal structure of Plasmodium falciparum hexose transporter PfHT1 bound with C3361

Summary for 6M2L

• Entry DOI: 10.2210/pdb6m2l/pdb
• Related: 6M20
• Descriptor: Hexose transporter 1, (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol (2 entities in total)
• Functional Keywords: mfs, hexose transporter, inhibitor, plasmodium falciparum, transport protein
• Biological source: Plasmodium falciparum
• Total number of polymer chains: 2
• Total formula weight: 113601.47

Authors

Jiang, X.,Yuan, Y.Y.,Zhang, S.,Wang, N.,Yan, C.Y.,Yan, N. (deposition date: 2020-02-27, release date: 2020-09-09, Last modification date: 2023-11-29)

• Primary citation: Jiang, X.,Yuan, Y.,Huang, J.,Zhang, S.,Luo, S.,Wang, N.,Pu, D.,Zhao, N.,Tang, Q.,Hirata, K.,Yang, X.,Jiao, Y.,Sakata-Kato, T.,Wu, J.W.,Yan, C.,Kato, N.,Yin, H.,Yan, N.; Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum.; Cell, 183:258-268.e12, 2020; PubMed: 32860739; DOI: 10.1016/j.cell.2020.08.015

Experimental method

X-RAY DIFFRACTION (3.7 Å)