6M2L
Crystal structure of Plasmodium falciparum hexose transporter PfHT1 bound with C3361
Summary for 6M2L
Entry DOI | 10.2210/pdb6m2l/pdb |
Related | 6M20 |
Descriptor | Hexose transporter 1, (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol (2 entities in total) |
Functional Keywords | mfs, hexose transporter, inhibitor, plasmodium falciparum, transport protein |
Biological source | Plasmodium falciparum |
Total number of polymer chains | 2 |
Total formula weight | 113601.47 |
Authors | |
Primary citation | Jiang, X.,Yuan, Y.,Huang, J.,Zhang, S.,Luo, S.,Wang, N.,Pu, D.,Zhao, N.,Tang, Q.,Hirata, K.,Yang, X.,Jiao, Y.,Sakata-Kato, T.,Wu, J.W.,Yan, C.,Kato, N.,Yin, H.,Yan, N. Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum. Cell, 183:258-268.e12, 2020 Cited by PubMed: 32860739DOI: 10.1016/j.cell.2020.08.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.7 Å) |
Structure validation
Download full validation report