Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 40 件
3OY5
DownloadVisualize
BU of 3oy5 by Molmil
The crystal structure of uPA complex with peptide inhibitor MH027 at pH7.4
分子名称: MH027, SULFATE ION, Urokinase-type plasminogen activator
著者Jiang, L.G, Andreasen, P.A, Huang, M.D.
登録日2010-09-22
公開日2011-08-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The binding mechanism of a peptidic cyclic serine protease inhibitor
J.Mol.Biol., 412, 2011
3OX7
DownloadVisualize
BU of 3ox7 by Molmil
The crystal structure of uPA complex with peptide inhibitor MH027 at pH4.6
分子名称: MH027, SULFATE ION, TETRAETHYLENE GLYCOL, ...
著者Jiang, L.G, Andreasen, P.A, Huang, M.D.
登録日2010-09-21
公開日2011-08-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献The binding mechanism of a peptidic cyclic serine protease inhibitor
J.Mol.Biol., 412, 2011
3OY6
DownloadVisualize
BU of 3oy6 by Molmil
The crystal structure of uPA complex with peptide inhibitor MH036 at pH4.6
分子名称: MH036, Urokinase-type plasminogen activator
著者Jiang, L.G, Andreasen, P.A, Huang, M.D.
登録日2010-09-22
公開日2011-08-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The binding mechanism of a peptidic cyclic serine protease inhibitor
J.Mol.Biol., 412, 2011
3MWI
DownloadVisualize
BU of 3mwi by Molmil
The complex crystal Structure of Urokianse and 5-nitro-1H-indole-2-amidine
分子名称: 5-nitro-1H-indole-2-carboximidamide, SULFATE ION, Urokinase-type plasminogen activator
著者Jiang, L.G, Yu, H.Y, Yuan, C, Huang, Z.X, Huang, M.D.
登録日2010-05-06
公開日2011-06-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献The complex crystal Structure of Urokianse and 5-nitro-1H-indole-2-amidine
To be Published
7DZD
DownloadVisualize
BU of 7dzd by Molmil
Crystal structure of uPA in complex with cleaved camostat
分子名称: 4-carbamimidamidobenzoic acid, TRIETHYLENE GLYCOL, Urokinase-type plasminogen activator
著者Jiang, L.G, Huang, M.D.
登録日2021-01-25
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of uPA in complex with cleaved camostat
To Be Published
7VM4
DownloadVisualize
BU of 7vm4 by Molmil
Crystal structure of uPA in complex with nafamostat
分子名称: 4-carbamimidamidobenzoic acid, TRIETHYLENE GLYCOL, Urokinase-type plasminogen activator
著者Jiang, L.G, Huang, M.D.
登録日2021-10-07
公開日2022-10-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structural study of the uPA-nafamostat complex reveals a covalent inhibitory mechanism of nafamostat.
Biophys.J., 121, 2022
7VM5
DownloadVisualize
BU of 7vm5 by Molmil
Crystal structure of uPA in complex with 4-guanidinobenzoic acid
分子名称: 4-carbamimidamidobenzoic acid, TRIETHYLENE GLYCOL, Urokinase-type plasminogen activator
著者Jiang, L.G, Huang, M.D.
登録日2021-10-07
公開日2022-10-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural study of the uPA-nafamostat complex reveals a covalent inhibitory mechanism of nafamostat.
Biophys.J., 121, 2022
7VM6
DownloadVisualize
BU of 7vm6 by Molmil
Crystal structure of uPA in complex with 6-amidino-2-naphthol
分子名称: 6-oxidanylnaphthalene-2-carboximidamide, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Jiang, L.G, Huang, M.D.
登録日2021-10-07
公開日2022-10-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural study of the uPA-nafamostat complex reveals a covalent inhibitory mechanism of nafamostat.
Biophys.J., 121, 2022
7VM7
DownloadVisualize
BU of 7vm7 by Molmil
Crystal structure of inactive uPA in complex with nafamostat
分子名称: (6-carbamimidoylnaphthalen-2-yl) 4-carbamimidamidobenzoate, Urokinase-type plasminogen activator chain B
著者Jiang, L.G, Huang, M.D.
登録日2021-10-07
公開日2022-11-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural study of the uPA-nafamostat complex reveals a covalent inhibitory mechanism of nafamostat.
Biophys.J., 121, 2022
5YC6
DownloadVisualize
BU of 5yc6 by Molmil
The crystal structure of uPA in complex with 4-Bromobenzylamirne at pH4.6
分子名称: 1-(4-BROMOPHENYL)METHANAMINE, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Jiang, L.G, Zhang, X, Huang, M.D.
登録日2017-09-06
公開日2018-10-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献Halogen bonding for the design of inhibitors by targeting the S1 pocket of serine proteases
Rsc Adv, 8, 2018
5YC7
DownloadVisualize
BU of 5yc7 by Molmil
The crystal structure of uPA in complex with 4-Bromobenzylamirne at pH7.4
分子名称: 1-(4-BROMOPHENYL)METHANAMINE, SULFATE ION, Urokinase-type plasminogen activator
著者Jiang, L.G, Zhang, X, Huang, M.D.
登録日2017-09-06
公開日2018-10-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Halogen bonding for the design of inhibitors by targeting the S1 pocket of serine proteases
Rsc Adv, 8, 2018
5Z1C
DownloadVisualize
BU of 5z1c by Molmil
The crystal structure of uPA in complex with 4-Iodobenzylamine at pH7.4
分子名称: 1-(4-iodophenyl)methanamine, Urokinase-type plasminogen activator
著者Jiang, L.G, Zhang, X, Luo, Z.P, Huang, M.D.
登録日2017-12-25
公開日2018-12-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Halogen bonding for the design of inhibitors by targeting the S1 pocket of serine proteases
Rsc Adv, 49, 2018
5YUP
DownloadVisualize
BU of 5yup by Molmil
Crystal Structure of the Fab fragment of FVIIa antibody mAb4F5
分子名称: the heavy chain of the Fab fragment of FVIIa antibody mAb4F5, the light chain of the Fab fragment of FVIIa antibody mAb4F5
著者Jiang, L.G, Persson, E, Huang, M.D.
登録日2017-11-22
公開日2019-06-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Crystal structure, epitope, and functional impact of an antibody against a superactive FVIIa provide insights into allosteric mechanism.
Res Pract Thromb Haemost, 3, 2019
5ZC5
DownloadVisualize
BU of 5zc5 by Molmil
uPA-NU-09F
分子名称: 3-azanyl-5-(azepan-1-yl)-N-carbamimidoyl-6-(4-fluoranyl-1-benzofuran-2-yl)pyrazine-2-carboxamide, Urokinase-type plasminogen activator chain B
著者Jiang, L.G, Buckley, B.J, Huang, M.D, Kelso, M.J, Ranson, M.
登録日2018-02-15
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.
J. Med. Chem., 61, 2018
6XVD
DownloadVisualize
BU of 6xvd by Molmil
Crystal structure of complex of urokinase and a upain-1 variant(W3F) in pH7.4 condition
分子名称: Urokinase-type plasminogen activator, upain-1-W3F
著者Xue, G.P, Xie, X, Zhou, Y, Yuan, C, Huang, M.D, Jiang, L.G.
登録日2020-01-21
公開日2020-02-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Insight to the residue in P2 position prevents the peptide inhibitor from being hydrolyzed by serine proteases.
Biosci.Biotechnol.Biochem., 84, 2020
8ITR
DownloadVisualize
BU of 8itr by Molmil
Crystal structure of lysophosphatidylcholine in complex with human serum albumin
分子名称: Albumin, [1-MYRISTOYL-GLYCEROL-3-YL]PHOSPHONYLCHOLINE
著者Wang, Y, Jiang, L.G, Huang, M.D.
登録日2023-03-22
公開日2024-01-31
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Crystal structures of human serum albumin in complex with lysophosphatidylcholine.
Biophys.J., 122, 2023
3G7N
DownloadVisualize
BU of 3g7n by Molmil
Crystal Structure of a Triacylglycerol Lipase from Penicillium Expansum at 1.3
分子名称: DI(HYDROXYETHYL)ETHER, Lipase, PENTAETHYLENE GLYCOL, ...
著者Bian, C.B, Yuan, C, Chen, L.Q, Edward, J.M, Lin, L, Jiang, L.G, Huang, Z.X, Huang, M.D.
登録日2009-02-10
公開日2010-02-23
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of a triacylglycerol lipase from Penicillium expansum at 1.3 A determined by sulfur SAD
Proteins, 78, 2010
6JYP
DownloadVisualize
BU of 6jyp by Molmil
Crystal structure of uPA_H99Y in complex with 3-azanyl-5-(azepan-1-yl)-N-[bis(azanyl)methylidene]-6-chloranyl-pyrazine-2-carboxamide
分子名称: 3-azanyl-5-(azepan-1-yl)-N-[bis(azanyl)methylidene]-6-chloranyl-pyrazine-2-carboxamide, SULFATE ION, Urokinase-type plasminogen activator
著者Buckley, B, Jiang, L.G, Huang, M.D, Kelso, M, Ranson, M.
登録日2019-04-27
公開日2020-05-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献uPA-HMA
To Be Published
6L05
DownloadVisualize
BU of 6l05 by Molmil
Crystal structure of uPA_H99Y in complex with 50F
分子名称: 3-azanyl-5-(azepan-1-yl)-6-(1-benzofuran-2-yl)-Ncarbamimidoyl-pyrazine-2-carboxamide, Urokinase-type plasminogen activator
著者Buckley, B, Jiang, L.G, Huang, M.D, Kelso, M, Ranson, M.
登録日2019-09-26
公開日2020-09-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Crystal structure of uPA_H99Y in complex with 50F
To Be Published
6L04
DownloadVisualize
BU of 6l04 by Molmil
Crystal structure of uPA_H99Y in complex with 31F
分子名称: 3-azanyl-5-(azepan-1-yl)-N-carbamimidoyl-6-(2,4-dimethoxypyrimidin-5-yl)pyrazine-2-carboxamide, Urokinase-type plasminogen activator
著者Buckley, B, Jiang, L.G, Huang, M.D, Kelso, M, Ranson, M.
登録日2019-09-26
公開日2020-09-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Crystal structure of uPA_H99Y in complex with 31F
To Be Published
6JYQ
DownloadVisualize
BU of 6jyq by Molmil
Crystal structure of uPA_H99Y in complex with 3-azanyl-5-(azepan-1-yl)-N-carbamimidoyl-6-(furan-2-yl)pyrazine-2-carboxamide
分子名称: 3-azanyl-5-(azepan-1-yl)-N-carbamimidoyl-6-(furan-2-yl)pyrazine-2-carboxamide, SULFATE ION, Urokinase-type plasminogen activator
著者Buckley, B, Jiang, L.G, Huang, M.D, Kelso, M, Ranson, M.
登録日2019-04-27
公開日2020-05-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献H99Y-6F-HMA-pH7
To Be Published
8ITT
DownloadVisualize
BU of 8itt by Molmil
Crystal structure of lysophosphatidylcholine in complex with human serum albumin and myristate
分子名称: Albumin, MYRISTIC ACID, [1-MYRISTOYL-GLYCEROL-3-YL]PHOSPHONYLCHOLINE
著者Wang, Y, Jiang, L.G, Huang, M.D.
登録日2023-03-22
公開日2024-01-31
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Crystal structures of human serum albumin in complex with lysophosphatidylcholine.
Biophys.J., 122, 2023
7WOK
DownloadVisualize
BU of 7wok by Molmil
Crystal structure of HSA soaked with cisplatin for one week
分子名称: Albumin, Cisplatin, PHOSPHATE ION
著者Chen, S.L, Yuan, C, Jiang, L.G, Luo, Z.P, Huang, M.D.
登録日2022-01-21
公開日2022-07-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystallographic analysis of interaction between cisplatin and human serum albumin: Effect of fatty acid.
Int.J.Biol.Macromol., 216, 2022
7WOJ
DownloadVisualize
BU of 7woj by Molmil
Crystal structure of HSA-Myr complex soaked with cisplatin for one week
分子名称: Albumin, Cisplatin, MYRISTIC ACID
著者Chen, S.L, Yuan, C, Jiang, L.G, Luo, Z.P, Huang, M.D.
登録日2022-01-21
公開日2022-07-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Crystallographic analysis of interaction between cisplatin and human serum albumin: Effect of fatty acid.
Int.J.Biol.Macromol., 216, 2022
6AG3
DownloadVisualize
BU of 6ag3 by Molmil
Crystal structure of uPA in complex with 3,5-bis(azanyl)-N-carbamimidoyl-6-(2,4-dimethoxypyrimidin-5-yl)pyrazine-2-carboxamide
分子名称: 3,5-bis(azanyl)-N-carbamimidoyl-6-(2,4-dimethoxypyrimidin-5-yl)pyrazine-2-carboxamide, Urokinase-type plasminogen activator
著者Buckley, B, Jiang, L.G, Majed, H, Huang, M.D, Kelso, M, Ranson, M.
登録日2018-08-09
公開日2019-09-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献uPA-HMA
To Be Published

 

12>

222926

件を2024-07-24に公開中

PDB statisticsPDBj update infoContact PDBjnumon