Summary for 5YC7
Entry DOI | 10.2210/pdb5yc7/pdb |
Descriptor | Urokinase-type plasminogen activator, 1-(4-BROMOPHENYL)METHANAMINE, SULFATE ION, ... (4 entities in total) |
Functional Keywords | halogen bonding, serine protease, upa, p1 group, protease inhibitors, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 27997.71 |
Authors | Jiang, L.G.,Zhang, X.,Huang, M.D. (deposition date: 2017-09-06, release date: 2018-10-03, Last modification date: 2023-11-22) |
Primary citation | Jiang, L.G.,Zhang, X.,Zhou, Y.,Chen, Y.Y.,Luo, Z.P.,Li, J.Y.,Yuan, C.,Huang, M.D. Halogen bonding for the design of inhibitors by targeting the S1 pocket of serine proteases Rsc Adv, 8:28189-28197, 2018 Cited by DOI: 10.1039/c8ra03145bPDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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