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PDB: 3272 件
5TFI
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Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with dGTP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
著者Wang, C, Aleksandrov, A.A, Yang, Z, Forouhar, F, Proctor, E, Kota, P, An, J, Kaplan, A, Khazanov, N, Boel, G, Stockwell, B.R, Senderowitz, H, Dokholyan, N.V, Riordan, J.R, Brouillette, C.G, Hunt, J.F.
登録日2016-09-25
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.891 Å)
主引用文献Thermodynamic correction of F508del-CFTR by ligand binding to a remote site in the mutated domain
To Be Published
5TBT
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BU of 5tbt by Molmil
Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase complexed with Cytidine
分子名称: 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, Purine nucleoside phosphorylase, SULFATE ION
著者Faheem, M, Torini, J.R, Romanello, L, Brandao-Neto, J, Pereira, H.M.
登録日2016-09-13
公開日2017-10-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleoside selectivity of PNPs.
PLoS ONE, 13, 2018
5TBU
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BU of 5tbu by Molmil
Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase complexed with Hypoxanthine
分子名称: DIMETHYL SULFOXIDE, HYPOXANTHINE, Purine nucleoside phosphorylase
著者Faheem, M, Torini, J.R, Romanello, L, Brandao-Neto, J, Pereira, H.M.
登録日2016-09-13
公開日2017-10-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleoside selectivity of PNPs.
PLoS ONE, 13, 2018
5TF7
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BU of 5tf7 by Molmil
Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
著者Wang, C, Aleksandrov, A.A, Yang, Z, Forouhar, F, Proctor, E, Kota, P, An, J, Kaplan, A, Khazanov, N, Boel, G, Stockwell, B.R, Senderowitz, H, Dokholyan, N.V, Riordan, J.R, Brouillette, C.G, Hunt, J.F.
登録日2016-09-24
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.931 Å)
主引用文献Thermodynamic correction of F508del-CFTR by ligand binding to a remote site in the mutated domain
To Be Published
5TFF
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BU of 5tff by Molmil
Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with UTP
分子名称: Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, URIDINE 5'-TRIPHOSPHATE
著者Wang, C, Aleksandrov, A.A, Yang, Z, Forouhar, F, Proctor, E, Kota, P, An, J, Kaplan, A, Khazanov, N, Boel, G, Stockwell, B.R, Senderowitz, H, Dokholyan, N.V, Riordan, J.R, Brouillette, C.G, Hunt, J.F.
登録日2016-09-25
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.891 Å)
主引用文献Thermodynamic correction of F508del-CFTR by ligand binding to a remote site in the mutated domain
To Be Published
5TGK
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BU of 5tgk by Molmil
Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with dATP
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
著者Wang, C, Aleksandrov, A.A, Yang, Z, Forouhar, F, Proctor, E, Kota, P, An, J, Kaplan, A, Khazanov, N, Boel, G, Stockwell, B.R, Senderowitz, H, Dokholyan, N.V, Riordan, J.R, Brouillette, C.G, Hunt, J.F.
登録日2016-09-28
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.912 Å)
主引用文献Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator.
J. Biol. Chem., 2018
5SWD
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BU of 5swd by Molmil
Structure of the adenine riboswitch aptamer domain in an intermediate-bound state
分子名称: ADENINE, MAGNESIUM ION, Vibrio vulnificus strain 93U204 chromosome II, ...
著者Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H.
登録日2016-08-08
公開日2016-11-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Nature, 541, 2017
5SWE
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Ligand-bound structure of adenine riboswitch aptamer domain converted in crystal from its ligand-free state using ligand mixing serial femtosecond crystallography
分子名称: ADENINE, Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain
著者Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H.
登録日2016-08-08
公開日2016-11-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Nature, 541, 2017
5UMS
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BU of 5ums by Molmil
Crystal structure of middle double PH domain of human FACT complex subunit SSRP1
分子名称: FACT complex subunit SSRP1
著者Su, D, Hu, Q, Thompson, J.R, Botuyan, M.V, Mer, G.
登録日2017-01-29
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.569 Å)
主引用文献Crystal structure of middle double PH domain of human FACT complex subunit SSRP1
To Be Published
5UMV
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BU of 5umv by Molmil
Crystal structure of the BRCT domain of S. cerevisiae Rev1
分子名称: DNA repair protein REV1
著者Lee, J, Xu, C, Thompson, J.R, Botuyan, M.V, Mer, G.
登録日2017-01-29
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of the BRCT domain of S. cerevisiae Rev1
To Be Published
5UP4
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BU of 5up4 by Molmil
Structure of the HIV-1 Capsid Protein and spacer peptide 1 by Cryo-EM
分子名称: HIV-1 Capsid Protein and spacer peptide 1
著者Perilla, J.R, Schirra, R, Zhang, P, Schulten, K.
登録日2017-02-01
公開日2017-12-06
最終更新日2017-12-13
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Quenching protein dynamics interferes with HIV capsid maturation.
Nat Commun, 8, 2017
5UOT
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BU of 5uot by Molmil
CryoEM structure of the helical assembly of full length MxB
分子名称: Interferon-induced GTP-binding protein Mx2
著者Perilla, J.R, Alvarez, F.J.D, Zhang, P, Schulten, K.
登録日2017-02-01
公開日2018-02-21
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献CryoEM structure of MxB reveals a novel oligomerization interface critical for HIV restriction.
Sci Adv, 3, 2017
5UW6
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BU of 5uw6 by Molmil
PCY1 in Complex with Follower Peptide and Covalent Inhibitor ZPP
分子名称: CALCIUM ION, N-BENZYLOXYCARBONYL-L-PROLYL-L-PROLINAL, Peptide cyclase 1, ...
著者Chekan, J.R, Nair, S.K.
登録日2017-02-20
公開日2017-05-31
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Characterization of the macrocyclase involved in the biosynthesis of RiPP cyclic peptides in plants.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5V9I
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BU of 5v9i by Molmil
Crystal structure of catalytic domain of G9a with MS0105
分子名称: GLYCEROL, Histone-lysine N-methyltransferase EHMT2, N~2~-cyclohexyl-N~4~-(1-ethylpiperidin-4-yl)-6,7-dimethoxy-N~2~-methylquinazoline-2,4-diamine, ...
著者Dong, A, Zeng, H, Liu, J, Xiong, Y, Babault, N, Jin, J, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Wu, H, Brown, P.J, Structural Genomics Consortium (SGC)
登録日2017-03-23
公開日2018-03-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystal structure of catalytic domain of G9a with MS0105
to be published
5ULC
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BU of 5ulc by Molmil
PLASMODIUM FALCIPARUM BROMODOMAIN-CONTAINING PROTEIN PF10_0328
分子名称: Bromodomain protein 1
著者Wernimont, A.K, Amaya, M.F, Lam, A, Ali, A, Zhang, A.Z, Kenzina, L, Lin, Y.H, MacKenzie, F, Kozieradzki, I, Cossar, D, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Weigelt, J, Hui, R, Walker, J.R, Qiu, W, Brand, V, Structural Genomics Consortium (SGC)
登録日2017-01-24
公開日2017-02-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献PLASMODIUM FALCIPARUM BROMODOMAIN-CONTAINING PROTEIN PF10_0328
To be published
5UMU
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BU of 5umu by Molmil
Crystal structure of the middle double PH domain of human FACT complex subunit SPT16
分子名称: ACETATE ION, FACT complex subunit SPT16, FORMIC ACID
著者Hu, Q, Thompson, J.R, Heroux, A, Su, D, Botuyan, M.V, Mer, G.
登録日2017-01-29
公開日2018-01-31
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献Crystal structure of the middle double PH domain of human FACT complex subunit SPT16
To Be Published
5SV4
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BU of 5sv4 by Molmil
Anti-Ricin A-chain Single Domain Antibody A3C8
分子名称: SULFATE ION, Single Domain Antibody A3C8
著者Compton, J.R, Legler, P.M.
登録日2016-08-04
公開日2016-10-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Stability of isolated antibody-antigen complexes as a predictive tool for selecting toxin neutralizing antibodies.
MAbs, 9, 2017
5SZX
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BU of 5szx by Molmil
Epstein-Barr virus Zta DNA binding domain homodimer in complex with methylated DNA
分子名称: DNA (5'-D(*AP*AP*GP*CP*AP*CP*TP*GP*AP*GP*(5CM)P*GP*AP*TP*GP*AP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*TP*CP*AP*TP*(5CM)P*GP*CP*TP*CP*AP*GP*TP*GP*CP*T)-3'), PHOSPHATE ION, ...
著者Hong, S, Horton, J.R, Cheng, X.
登録日2016-08-15
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta.
Nucleic Acids Res., 45, 2017
5UZA
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BU of 5uza by Molmil
Adenine riboswitch aptamer domain labelled with iodo-uridine by position-selective labelling of RNA (PLOR)
分子名称: ADENINE, MAGNESIUM ION, RNA (71-MER)
著者Liu, Y, Stagno, J.R, Wang, Y.-X.
登録日2017-02-25
公開日2018-02-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Incorporation of isotopic, fluorescent, and heavy-atom-modified nucleotides into RNAs by position-selective labeling of RNA.
Nat Protoc, 13, 2018
5UW3
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PCY1 in Complex with Follower Peptide
分子名称: CACODYLATE ION, Peptide cyclase 1, Presegetalin A1
著者Chekan, J.R, Nair, S.K.
登録日2017-02-20
公開日2017-05-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Characterization of the macrocyclase involved in the biosynthesis of RiPP cyclic peptides in plants.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5V9P
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BU of 5v9p by Molmil
Crystal structure of pyrrolidine amide inhibitor [(3S)-3-(4-bromo-1H-pyrazol-1-yl)pyrrolidin-1-yl][3-(propan-2-yl)-1H-pyrazol-5-yl]methanone (compound 35) in complex with KDM5A
分子名称: Lysine-specific demethylase 5A, NICKEL (II) ION, SULFATE ION, ...
著者Kiefer, J.R, Liang, J, Vinogradova, M.
登録日2017-03-23
公開日2017-05-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
5UZW
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BU of 5uzw by Molmil
PCY1 G696Insertion Variant in Complex with Follower Peptide and the Covalent Inhibitor ZPP
分子名称: CALCIUM ION, N-BENZYLOXYCARBONYL-L-PROLYL-L-PROLINAL, Peptide cyclase 1, ...
著者Chekan, J.R, Nair, S.K.
登録日2017-02-27
公開日2017-05-31
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Characterization of the macrocyclase involved in the biosynthesis of RiPP cyclic peptides in plants.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UMR
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BU of 5umr by Molmil
Crystal structure of N-terminal domain of human FACT complex subunit SSRP1
分子名称: FACT complex subunit SSRP1
著者Su, D, Hu, Q, Thompson, J.R, Heroux, A, Botuyan, M.V, Mer, G.
登録日2017-01-29
公開日2018-01-31
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献Crystal structure of N-terminal domain of human FACT complex subunit SSRP1
To Be Published
5UMT
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BU of 5umt by Molmil
Crystal structure of N-terminal domain of human FACT complex subunit SPT16
分子名称: 1,2-ETHANEDIOL, FACT complex subunit SPT16, GLYCEROL
著者Su, D, Hu, Q, Thompson, J.R, Botuyan, M.V, Mer, G.
登録日2017-01-29
公開日2018-01-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.092 Å)
主引用文献Crystal structure of N-terminal domain of human FACT complex subunit SPT16
To Be Published
5TFA
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BU of 5tfa by Molmil
Nucleotide-binding domain 1 of the human cystic fibrosis transmembrane conductance regulator (CFTR) with dUTP
分子名称: Cystic fibrosis transmembrane conductance regulator, DEOXYURIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Wang, C, Aleksandrov, A.A, Yang, Z, Forouhar, F, Proctor, E, Kota, P, An, J, Kaplan, A, Khazanov, N, Boel, G, Stockwell, B.R, Senderowitz, H, Dokholyan, N.V, Riordan, J.R, Brouillette, C.G, Hunt, J.F.
登録日2016-09-24
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Thermodynamic correction of F508del-CFTR by ligand binding to a remote site in the mutated domain
To Be Published

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件を2024-07-10に公開中

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