5UP4

Structure of the HIV-1 Capsid Protein and spacer peptide 1 by Cryo-EM

Summary for 5UP4

Entry DOI	10.2210/pdb5up4/pdb
EMDB information	8582
Descriptor	HIV-1 Capsid Protein and spacer peptide 1 (1 entity in total)
Functional Keywords	hiv-1, spacer peptide 1, capsid protein, cryoem, helical assembly, reconstruction, virus
Biological source	Human immunodeficiency virus 1
Cellular location	Host cytoplasm . Host nucleus . Matrix protein p17: Virion . Virion : B6DRA0
Total number of polymer chains	18
Total formula weight	443776.82
Authors	Perilla, J.R.,Schirra, R.,Zhang, P.,Schulten, K. (deposition date: 2017-02-01, release date: 2017-12-06, Last modification date: 2017-12-13)
Primary citation	Wang, M.,Quinn, C.M.,Perilla, J.R.,Zhang, H.,Shirra, R.,Hou, G.,Byeon, I.J.,Suiter, C.L.,Ablan, S.,Urano, E.,Nitz, T.J.,Aiken, C.,Freed, E.O.,Zhang, P.,Schulten, K.,Gronenborn, A.M.,Polenova, T. Quenching protein dynamics interferes with HIV capsid maturation. Nat Commun, 8:1779-1779, 2017 Cited by PubMed: 29176596 DOI: 10.1038/s41467-017-01856-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (9 Å)

Structure validation