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PDB: 2437 件

7KIU
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Structure of recombinant human DNase1L3 in complex with Mg2+
分子名称: Deoxyribonuclease gamma, MAGNESIUM ION
著者McCord, J.J, Keyel, P.A, Sutton, R.B.
登録日2020-10-24
公開日2021-12-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural features of Dnase1L3 responsible for serum antigen clearance.
Commun Biol, 5, 2022
7NVO
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BU of 7nvo by Molmil
Human TRiC complex in open state with nanobody bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ...
著者Kelly, J.J, Chi, G, Bulawa, C, Paavilainen, V.O, Bountra, C, Huiskonen, J.T, Yue, W.
登録日2021-03-15
公開日2022-03-02
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Snapshots of actin and tubulin folding inside the TRiC chaperonin.
Nat.Struct.Mol.Biol., 29, 2022
7NVL
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Human TRiC complex in closed state with nanobody bound (Consensus Map)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ...
著者Kelly, J.J, Chi, G, Bulawa, C, Paavilainen, V.O, Bountra, C, Huiskonen, J.T, Yue, W, Structural Genomics Consortium (SGC)
登録日2021-03-15
公開日2022-03-02
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Snapshots of actin and tubulin folding inside the TRiC chaperonin.
Nat.Struct.Mol.Biol., 29, 2022
7NVN
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Human TRiC complex in closed state with nanobody and tubulin bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ...
著者Kelly, J.J, Chi, G, Bulawa, C, Paavilainen, V.O, Bountra, C, Huiskonen, J.T, Yue, W.
登録日2021-03-15
公開日2022-03-02
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Snapshots of actin and tubulin folding inside the TRiC chaperonin.
Nat.Struct.Mol.Biol., 29, 2022
7NVM
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Human TRiC complex in closed state with nanobody Nb18, actin and PhLP2A bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Actin, ...
著者Kelly, J.J, Chi, G, Bulawa, C, Paavilainen, V.O, Bountra, C, Huiskonen, J.T, Yue, W, Structural Genomics Consortium (SGC)
登録日2021-03-15
公開日2022-03-02
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Snapshots of actin and tubulin folding inside the TRiC chaperonin.
Nat.Struct.Mol.Biol., 29, 2022
1PG5
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BU of 1pg5 by Molmil
CRYSTAL STRUCTURE OF THE UNLIGATED (T-STATE) ASPARTATE TRANSCARBAMOYLASE FROM THE EXTREMELY THERMOPHILIC ARCHAEON SULFOLOBUS ACIDOCALDARIUS
分子名称: Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, ZINC ION
著者De Vos, D, Van Petegem, F, Remaut, H, Legrain, C, Glansdorff, N, Van Beeumen, J.J.
登録日2003-05-27
公開日2004-06-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of T State Aspartate Carbamoyltransferase of the Hyperthermophilic Archaeon Sulfolobus acidocaldarius.
J.Mol.Biol., 339, 2004
7JVK
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BU of 7jvk by Molmil
Structure of the M101A variant of the SidA ornithine hydroxylase with the FAD in the "out" conformation
分子名称: ACETATE ION, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Tanner, J.J, Campbell, A.C.
登録日2020-08-21
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Determinants of Flavin Dynamics in a Class B Monooxygenase.
Biochemistry, 59, 2020
3CL2
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BU of 3cl2 by Molmil
N1 Neuraminidase N294S + Oseltamivir
分子名称: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase
著者Collins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J.
登録日2008-03-18
公開日2008-05-20
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.538 Å)
主引用文献Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
4XSJ
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BU of 4xsj by Molmil
Crystal structure of the N-terminal domain of the human mitochondrial calcium uniporter fused with T4 lysozyme
分子名称: Lysozyme,Calcium uniporter protein, mitochondrial, SULFATE ION
著者Lee, Y, Min, C.K, Kim, T.G, Song, H.K, Lim, Y, Kim, D, Shin, K, Kang, M, Kang, J.Y, Youn, H.-S, Lee, J.-G, An, J.Y, Park, K.R, Lim, J.J, Kim, J.H, Kim, J.H, Park, Z.Y, Kim, Y.-S, Wang, J, Kim, D.H, Eom, S.H.
登録日2015-01-22
公開日2015-09-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter.
Embo Rep., 16, 2015
5A4C
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BU of 5a4c by Molmil
FGFR1 ligand complex
分子名称: 1,2-ETHANEDIOL, 1-tert-butyl-3-[2-[3-(diethylamino)propylamino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]urea, FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, ...
著者Klein, T, Vajpai, N, Phillips, J.J, Davies, G, Holdgate, G.A, Phillips, C, Tucker, J.A, Norman, R.A, Scott, A.S, Higazi, D.R, Lowe, D, Thompson, G.S, Breeze, A.L.
登録日2015-06-05
公開日2015-08-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structural and Dynamic Insights Into the Energetics of Activation Loop Rearrangement in Fgfr1 Kinase.
Nat.Commun., 6, 2015
4ZVY
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BU of 4zvy by Molmil
Structure of human ALDH7A1 complexed with NAD+ in space group P4212
分子名称: Alpha-aminoadipic semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Tanner, J.J.
登録日2015-05-18
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis of Substrate Recognition by Aldehyde Dehydrogenase 7A1.
Biochemistry, 54, 2015
3DSH
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BU of 3dsh by Molmil
Crystal structure of dimeric interferon regulatory factor 5 (IRF-5) transactivation domain
分子名称: Interferon regulatory factor 5
著者Chen, W, Lam, S.S, Srinath, H, Jiang, Z, Correia, J.J, Schiffer, C, Fitzgerald, K.A, Lin, K, Royer Jr, W.E.
登録日2008-07-12
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5.
Nat.Struct.Mol.Biol., 15, 2008
7MUA
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BU of 7mua by Molmil
Structure of the adeno-associated virus 9 capsid at pH pH 5.5 in complex with terminal galactose
分子名称: Capsid protein VP1, beta-D-galactopyranose
著者Penzes, J.J, Chipman, P, Bhattacharya, N, Zeher, A, Huang, R, McKenna, R, Agbandje-McKenna, M.
登録日2021-05-14
公開日2021-06-09
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Adeno-associated Virus 9 Structural Rearrangements Induced by Endosomal Trafficking pH and Glycan Attachment.
J.Virol., 95, 2021
4XTB
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BU of 4xtb by Molmil
Crystal structure of the N-terminal domain of the human mitochondrial calcium uniporter
分子名称: Calcium uniporter protein, mitochondrial, TETRAETHYLENE GLYCOL
著者Lee, Y, Min, C.K, Kim, T.G, Song, H.K, Lim, Y, Kim, D, Shin, K, Kang, M, Kang, J.Y, Youn, H.-S, Lee, J.-G, An, J.Y, Park, K.R, Lim, J.J, Kim, J.H, Kim, J.H, Park, Z.Y, Kim, Y.-S, Wang, J, Kim, D.H, Eom, S.H.
登録日2015-01-23
公開日2015-09-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter.
Embo Rep., 16, 2015
7O2L
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BU of 7o2l by Molmil
Yeast 20S proteasome in complex with the covalently bound inhibitor b-lactone (2R,3S)-3-isopropyl-4-oxo-2-oxetane-carboxylate (IOC)
分子名称: (2 {R},3 {S})-3-methanoyl-4-methyl-2-hydroxy-pentanoic acid, 20S proteasome, BJ4_G0020160.mRNA.1.CDS.1, ...
著者Shi, Y.M, Hirschmann, M, Shi, Y.N, Shabbir, A, Abebew, D, Tobias, N.J, Gruen, P, Crames, J.J, Poeschel, L, Kuttenlochner, W, Richter, C, Herrmann, J, Mueller, R, Thanwisai, A, Pidot, S.J, Stinear, T.P, Groll, M, Kim, Y, Bode, H.
登録日2021-03-30
公開日2022-04-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria.
Nat.Chem., 14, 2022
5AGT
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BU of 5agt by Molmil
Crystal structure of the LeuRS editing domain of Mycobacterium tuberculosis in complex with the adduct (S)-3-(Aminomethyl)-4-chloro-7-ethoxybenzo[c][1,2]oxaborol-1(3H)-ol-AMP
分子名称: 4-Chloro-3-aminomethyl-7-[ethoxy]-3H-benzo[C][1,2]oxaborol-1-ol modified adenosine, GLYCEROL, LEUCINE--TRNA LIGASE, ...
著者Palencia, A, Li, X, Alley, M.R.K, Ding, C, Easom, E.E, Hernandez, V, Meewan, M, Mohan, M, Rock, F.L, Franzblau, S.G, Wang, Y, Lenaerts, A.J, Parish, T, Cooper, C.B, Waters, M.G, Ma, Z, Mendoza, A, Barros, D, Cusack, S, Plattner, J.J.
登録日2015-02-03
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium Tuberculosis that Target Leucyl-tRNA Synthetase.
Antimicrob.Agents Chemother., 60, 2016
1YCZ
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BU of 1ycz by Molmil
Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Thermotoga maritima
分子名称: GLYCEROL, UvrABC system protein C
著者Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C.
登録日2004-12-23
公開日2005-03-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into the first incision reaction during nucleotide excision repair
Embo J., 24, 2005
4Z3N
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BU of 4z3n by Molmil
Crystal structure of the MATE transporter ClbM
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CACODYLATE ION, Putative drug/sodium antiporter
著者Mousa, J.J, Bruner, S.D.
登録日2015-03-31
公開日2016-01-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献MATE transport of the E. coli-derived genotoxin colibactin.
Nat Microbiol, 1, 2016
1MA1
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BU of 1ma1 by Molmil
Structure and properties of the atypical iron superoxide dismutase from Methanobacterium thermoautotrophicum
分子名称: FE (III) ION, superoxide dismutase
著者Adams, J.J, Anderson, B.F, Renault, J.P, Verchere-Beaur, C, Morgenstern-Badarau, I, Jameson, G.B.
登録日2002-07-31
公開日2002-08-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and properties of the atypical iron superoxide dismutase from Methanobacterium thermoautotrophicum
To be published
4ZJ8
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BU of 4zj8 by Molmil
Structures of the human OX1 orexin receptor bound to selective and dual antagonists
分子名称: OLEIC ACID, [(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone, human OX1R fusion protein to P.abysii glycogen synthase
著者Yin, J, Brautigam, C.A, Shao, Z, Clark, L, Harrell, C.M, Gotter, A.L, Coleman, P, Renger, J.J, Rosenbaum, D.M.
登録日2015-04-29
公開日2016-03-09
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.751 Å)
主引用文献Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors.
Nat.Struct.Mol.Biol., 23, 2016
7KOB
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BU of 7kob by Molmil
Crystal structure of antigen 43b from Escherichia coli CFT073
分子名称: Antigen 43b, GLYCEROL
著者Martinez-Ortiz, G.C, Hor, L, Paxman, J.J, Heras, B.
登録日2020-11-07
公開日2022-03-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Variation of Antigen 43 self-association modulates bacterial compacting within aggregates and biofilms.
NPJ Biofilms Microbiomes, 8, 2022
7KOH
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BU of 7koh by Molmil
Crystal structure of antigen 43 from Escherichia coli EDL933
分子名称: Antigen 43, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Vo, J.L, Paxman, J.J, Heras, B.
登録日2020-11-09
公開日2022-03-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Variation of Antigen 43 self-association modulates bacterial compacting within aggregates and biofilms.
NPJ Biofilms Microbiomes, 8, 2022
7KO9
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BU of 7ko9 by Molmil
Crystal structure of antigen 43 from uropathogenic Escherichia coli UTI89
分子名称: AidA-I family adhesin, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
著者Vo, J.L, Hor, L, Paxman, J.J, Heras, B.
登録日2020-11-07
公開日2022-03-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Variation of Antigen 43 self-association modulates bacterial compacting within aggregates and biofilms.
NPJ Biofilms Microbiomes, 8, 2022
7A9D
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BU of 7a9d by Molmil
Crystal structure of H12 Haemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin
著者Xiong, X, Walker, P, Zhang, J, Gamblin, S, Skehel, J.J.
登録日2020-09-01
公開日2020-12-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Hemagglutinin Structure and Activities.
Cold Spring Harb Perspect Med, 11, 2021
1XF2
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BU of 1xf2 by Molmil
Structure of Fab DNA-1 complexed with dT3
分子名称: 5'-D(*TP*TP*T)-3', SULFATE ION, antibody heavy chain Fab, ...
著者Schuermann, J.P, Prewitt, S.P, Deutscher, S.L, Tanner, J.J.
登録日2004-09-13
公開日2005-04-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Evidence for Structural Plasticity of Heavy Chain Complementarity-determining Region 3 in Antibody-ssDNA Recognition
J.Mol.Biol., 347, 2005

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