5A4C
FGFR1 ligand complex
Summary for 5A4C
Entry DOI | 10.2210/pdb5a4c/pdb |
Related | 5A46 |
Descriptor | FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B, SULFATE ION, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | transferase, kinase |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cell membrane; Single-pass type I membrane protein: P11362 |
Total number of polymer chains | 2 |
Total formula weight | 72174.65 |
Authors | Klein, T.,Vajpai, N.,Phillips, J.J.,Davies, G.,Holdgate, G.A.,Phillips, C.,Tucker, J.A.,Norman, R.A.,Scott, A.S.,Higazi, D.R.,Lowe, D.,Thompson, G.S.,Breeze, A.L. (deposition date: 2015-06-05, release date: 2015-08-05, Last modification date: 2024-05-08) |
Primary citation | Klein, T.,Vajpai, N.,Phillips, J.J.,Davies, G.,Holdgate, G.A.,Phillips, C.,Tucker, J.A.,Norman, R.A.,Scott, A.D.,Higazi, D.R.,Lowe, D.,Thompson, G.S.,Breeze, A.L. Structural and Dynamic Insights Into the Energetics of Activation Loop Rearrangement in Fgfr1 Kinase. Nat.Commun., 6:7877-, 2015 Cited by PubMed: 26203596DOI: 10.1038/NCOMMS8877 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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