7KIU
Structure of recombinant human DNase1L3 in complex with Mg2+
Summary for 7KIU
Entry DOI | 10.2210/pdb7kiu/pdb |
Descriptor | Deoxyribonuclease gamma, MAGNESIUM ION (3 entities in total) |
Functional Keywords | nuclease, dna hydrolase, apoptosis, lupus, systemic lupus erythematosus, sle, dna clearance, metal ion nuclease, net clearance, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 131381.21 |
Authors | McCord, J.J.,Keyel, P.A.,Sutton, R.B. (deposition date: 2020-10-24, release date: 2021-12-01, Last modification date: 2023-10-18) |
Primary citation | McCord, J.J.,Engavale, M.,Masoumzadeh, E.,Villarreal, J.,Mapp, B.,Latham, M.P.,Keyel, P.A.,Sutton, R.B. Structural features of Dnase1L3 responsible for serum antigen clearance. Commun Biol, 5:825-825, 2022 Cited by PubMed: 35974043DOI: 10.1038/s42003-022-03755-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.22 Å) |
Structure validation
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