7KIU

Structure of recombinant human DNase1L3 in complex with Mg2+

Summary for 7KIU

Entry DOI	10.2210/pdb7kiu/pdb
Descriptor	Deoxyribonuclease gamma, MAGNESIUM ION (3 entities in total)
Functional Keywords	nuclease, dna hydrolase, apoptosis, lupus, systemic lupus erythematosus, sle, dna clearance, metal ion nuclease, net clearance, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	131381.21
Authors	McCord, J.J.,Keyel, P.A.,Sutton, R.B. (deposition date: 2020-10-24, release date: 2021-12-01, Last modification date: 2023-10-18)
Primary citation	McCord, J.J.,Engavale, M.,Masoumzadeh, E.,Villarreal, J.,Mapp, B.,Latham, M.P.,Keyel, P.A.,Sutton, R.B. Structural features of Dnase1L3 responsible for serum antigen clearance. Commun Biol, 5:825-825, 2022 Cited by PubMed: 35974043 DOI: 10.1038/s42003-022-03755-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.22 Å)

Structure validation