7KIU

Structure of recombinant human DNase1L3 in complex with Mg2+

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Deoxyribonuclease gamma	polymer	281	32772.4	4	UniProt (Q13609) Pfam (PF03372)	Homo sapiens (Human)	DNase gamma,DNase I homolog protein DHP2,Liver and spleen DNase,LSD,Deoxyribonuclease I-like 3,DNase I-like 3,DNase1L3
2	E, F, G, H, I... (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	12	Chemie (MG)
3	Q, R, S, T (A, B, C, D)	water	water		18.0	174	Chemie (HOH)

Sequence modifications

A, B, C, D: 21 - 282 (UniProt: Q13609)

PDB	External Database	Details
Gly 2	-	expression tag
Asp 3	-	expression tag
Ile 4	-	expression tag
Thr 5	-	expression tag
His 6	-	expression tag
Met 7	-	expression tag
Ala 8	-	expression tag
Ser 9	-	expression tag
Met 10	-	expression tag
Thr 11	-	expression tag
Gly 12	-	expression tag
Gly 13	-	expression tag
Gln 14	-	expression tag
Gln 15	-	expression tag
Met 16	-	expression tag
Gly 17	-	expression tag
Arg 18	-	expression tag
Asp 19	-	expression tag
Pro 20	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	131089.5
Non-Polymers*	Number of molecules	12
	Total formula weight	291.7
All*	Total formula weight	131381.2

*Water molecules are not included.