7MUA

Structure of the adeno-associated virus 9 capsid at pH pH 5.5 in complex with terminal galactose

This is a non-PDB format compatible entry.

Summary for 7MUA

• Entry DOI: 10.2210/pdb7mua/pdb
• EMDB information: 23973 23986 23993 23999 24000 24003
• Descriptor: Capsid protein VP1, beta-D-galactopyranose (2 entities in total)
• Functional Keywords: adeno-associated virus, ph, phospholipase-a2, capsid, gene therapy, aav9, dependoparvovirus, intracellular trafficking, endosome, virus like particle, galactose, glycan attachment
• Biological source: Adeno-associated virus 9
• Total number of polymer chains: 60
• Total formula weight: 3519274.20

Authors

Penzes, J.J.,Chipman, P.,Bhattacharya, N.,Zeher, A.,Huang, R.,McKenna, R.,Agbandje-McKenna, M. (deposition date: 2021-05-14, release date: 2021-06-09, Last modification date: 2021-09-22)

• Primary citation: Penzes, J.J.,Chipman, P.,Bhattacharya, N.,Zeher, A.,Huang, R.,McKenna, R.,Agbandje-McKenna, M.; Adeno-associated Virus 9 Structural Rearrangements Induced by Endosomal Trafficking pH and Glycan Attachment.; J.Virol., 95:e0084321-e0084321, 2021; PubMed: 34260280; DOI: 10.1128/JVI.00843-21

Experimental method

ELECTRON MICROSCOPY (2.68 Å)