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PDB: 6634 件

2HO2
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Structure of human FE65-WW domain in complex with hMena peptide.
分子名称: Amyloid beta A4 protein-binding family B member 1, GLYCEROL, Protein enabled homolog
著者Meiyappan, M, Birrane, G, Ladias, J.A.
登録日2006-07-13
公開日2007-07-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Structural Basis for Polyproline Recognition by the FE65 WW Domain.
J.Mol.Biol., 372, 2007
2HIL
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Structure of the Neisseria gonorrhoeae Type IV pilus filament from x-ray crystallography and electron cryomicroscopy
分子名称: Fimbrial protein, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, alpha-D-galactopyranose-(1-3)-2,4-bisacetamido-2,4-dideoxy-beta-D-glucopyranose
著者Craig, L, Volkmann, N, Egelman, E.H, Tainer, J.A.
登録日2006-06-29
公開日2006-09-12
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (12.5 Å)
主引用文献Type IV Pilus Structure by Cryo-Electron Microscopy and Crystallography: Implications for Pilus Assembly and Functions.
Mol.Cell, 23, 2006
2HWO
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Crystal structure of Src kinase domain in complex with covalent inhibitor
分子名称: GLYCEROL, N-(4-PHENYLAMINO-QUINAZOLIN-6-YL)-ACRYLAMIDE, Proto-oncogene tyrosine-protein kinase Src
著者Rauh, D, Blair, J.A, Shokat, K.M.
登録日2006-08-01
公開日2007-02-27
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-guided development of affinity probes for tyrosine kinases using chemical genetics.
Nat.Chem.Biol., 3, 2007
2HWP
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Crystal structure of Src kinase domain in complex with covalent inhibitor PD168393
分子名称: N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDE, Proto-oncogene tyrosine-protein kinase Src
著者Rauh, D, Blair, J.A, Shokat, K.M.
登録日2006-08-01
公開日2007-02-27
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Structure-guided development of affinity probes for tyrosine kinases using chemical genetics.
Nat.Chem.Biol., 3, 2007
2HXT
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Crystal structure of L-Fuconate Dehydratase from Xanthomonas campestris liganded with Mg++ and D-erythronohydroxamate
分子名称: (2R,3R)-N,2,3,4-TETRAHYDROXYBUTANAMIDE, L-fuconate dehydratase, MAGNESIUM ION
著者Fedorov, A.A, Fedorov, E.V, Yew, W.S, Rakus, J.F, Gerlt, J.A, Almo, S.C.
登録日2006-08-03
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Evolution of Enzymatic Activities in the Enolase Superfamily: l-Fuconate Dehydratase from Xanthomonas campestris.
Biochemistry, 45, 2006
2L68
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Solution Structure of Human Holo L-FABP
分子名称: Fatty acid-binding protein, liver
著者Cai, J, Luecke, C, Chen, Z, Qiao, Y, Klimtchuk, E.S, Hamilton, J.A.
登録日2010-11-17
公開日2011-11-23
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure and backbone dynamics of human liver fatty acid binding protein: fatty acid binding revisited.
Biophys.J., 102, 2012
2L96
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Solution structure of LAK160-P7
分子名称: LAK160-P7
著者Vermeer, L.S, Bui, T.T, Lan, Y, Jumagulova, E, Kozlowska, J, McIntyre, C, Drake, A.F, Mason, J.A.
登録日2011-02-01
公開日2012-02-01
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The role of proline induced conformational flexibility in determining the antibacterial potency of linear cationic alpha-helical peptides
To be Published
2GDQ
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Crystal structure of mandelate racemase/muconate lactonizing enzyme from Bacillus subtilis at 1.8 A resolution
分子名称: yitF
著者Malashkevich, V.N, Toro, R, Sauder, J.M, Schwinn, K.D, Emtage, S, Thompson, D.A, Rutter, M.E, Dickey, M, Groshong, C, Bain, K.T, Adams, J.M, Reyes, C, Rooney, I, Powell, A, Boice, A, Gheyi, T, Ozyurt, S, Atwell, S, Wasserman, S.R, Burley, S.K, Sali, A, Babbitt, P, Pieper, U, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-03-16
公開日2006-04-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of mandelate racemase/muconate lactonizing enzyme from Bacillus subtilis at 1.8 A resolution
To be Published
2FZ4
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Crystal Structure of the N-terminal half of Archaeoglobus Fulgidus XPB
分子名称: DNA repair protein RAD25
著者Fan, L, Tainer, J.A.
登録日2006-02-09
公開日2006-04-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conserved XPB Core Structure and Motifs for DNA Unwinding: Implications for Pathway Selection of Transcription or Excision Repair.
Mol.Cell, 22, 2006
2G1Z
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X-ray structure of the oligonucleotide sequence d(AAATTT)
分子名称: 5'-D(*AP*AP*AP*TP*TP*T)-3'
著者Valls, N, Santaolalla, A, Campos, J.L, Subirana, J.A.
登録日2006-02-15
公開日2006-03-21
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Packing features of the all-AT oligonucleotide d(AAATTT).
J.Biomol.Struct.Dyn., 24, 2007
2JGX
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Structure of CCP module 7 of complement factor H - The AMD Not at risk varient (402Y)
分子名称: COMPLEMENT FACTOR H
著者Herbert, A.P, Deakin, J.A, Schmidt, C.Q, Blaum, B.S, Egan, C, Ferreira, V.P, Pangburn, M.K, Lyon, M, Uhrin, D, Barlow, P.N.
登録日2007-02-16
公開日2007-03-20
最終更新日2018-05-02
実験手法SOLUTION NMR
主引用文献Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism.
J. Biol. Chem., 282, 2007
2JH6
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Human Thrombin Hirugen Inhibitor complex
分子名称: 2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHANESULFONAMIDE, CALCIUM ION, HIRUDIN IIIA, ...
著者Senger, S, Chan, C, Convery, M.A, Hubbard, J.A, Young, R.J, Shah, G.P, Watson, N.S.
登録日2007-02-20
公開日2007-05-08
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Sulfonamide-Related Conformational Effects and Their Importance in Structure-Based Design.
Bioorg.Med.Chem.Lett., 17, 2007
2JYD
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Structure of the fifth zinc finger of Myelin Transcription Factor 1
分子名称: F5 domain of Myelin transcription factor 1, ZINC ION
著者Gamsjaeger, R, Swanton, M.K, Kobus, F.J, Lehtomaki, E, Lowry, J.A, Kwan, A.H, Matthews, J.M, Mackay, J.P.
登録日2007-12-12
公開日2008-01-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural and biophysical analysis of the DNA binding properties of myelin transcription factor 1.
J.Biol.Chem., 283, 2008
2JIY
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PHOTOSYNTHETIC REACTION CENTER MUTANT WITH ALA M149 REPLACED WITH TRP (CHAIN M, AM149W)
分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ...
著者Fyfe, P.K, Potter, J.A, Cheng, J, Williams, C.M, Watson, A.J, Jones, M.R.
登録日2007-07-03
公開日2007-09-04
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Responses to Cavity-Creating Mutations in an Integral Membrane Protein.
Biochemistry, 46, 2007
2JJ0
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PHOTOSYNTHETIC REACTION CENTER MUTANT WITH ALA M248 REPLACED WITH TRP (CHAIN M, AM248W)
分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ...
著者Fyfe, P.K, Potter, J.A, Cheng, J, Williams, C.M, Watson, A.J, Jones, M.R.
登録日2007-07-03
公開日2007-09-04
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Responses to Cavity-Creating Mutations in an Integral Membrane Protein.
Biochemistry, 46, 2007
2JJ3
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Estrogen receptor beta ligand binding domain in complex with a Benzopyran agonist
分子名称: (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL, ESTROGEN RECEPTOR BETA
著者Norman, B.H, Richardson, T.I, Dodge, J.A, Pfeifer, L.A, Durst, G.L, Wang, Y, Durbin, J.D, Krishnan, V, Dinn, S.R, Liu, S, Reilly, J.E, Ryter, K.T.
登録日2007-07-03
公開日2007-08-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Benzopyrans as Selective Estrogen Receptor Beta Agonists (Serbas). Part 4: Functionalization of the Benzopyran A-Ring.
Bioorg.Med.Chem.Lett., 17, 2007
2JQ4
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Complete resonance assignments and solution structure calculation of ATC2521 (NESG ID: AtT6) from Agrobacterium tumefaciens
分子名称: Hypothetical protein Atu2571
著者Srisailam, S, Lemak, A, Yee, A, Karra, M.D, Lukin, J.A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG)
登録日2007-05-29
公開日2007-06-12
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution Structure of a protein (ATC2521)of unknown function from Agrobacterium tumefaciens
To be Published
2JGW
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Structure of CCP module 7 of complement factor H - The AMD at risk varient (402H)
分子名称: COMPLEMENT FACTOR H
著者Herbert, A.P, Deakin, J.A, Schmidt, C.Q, Blaum, B.S, Egan, C, Ferreira, V.P, Pangburn, M.K, Lyon, M, Uhrin, D, Barlow, P.N.
登録日2007-02-16
公開日2007-03-20
最終更新日2018-05-02
実験手法SOLUTION NMR
主引用文献Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism.
J. Biol. Chem., 282, 2007
2JN4
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Solution NMR Structure of Protein RP4601 from Rhodopseudomonas palustris. Northeast Structural Genomics Consortium Target RpT2; Ontario Center for Structural Proteomics Target RP4601.
分子名称: Hypothetical protein fixU, nifT
著者Lemak, A, Srisailam, S, Yee, A, Karra, M.D, Lukin, J.A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG)
登録日2006-12-22
公開日2007-01-23
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution structure of a hypothetical protein RP4601 from Rhodopseudomonas palustris
To be Published
2JF9
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ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH A TAMOXIFEN-SPECIFIC PEPTIDE ANTAGONIST
分子名称: 1,2-ETHANEDIOL, 4-HYDROXYTAMOXIFEN, AB5 PEPTIDE, ...
著者Heldring, N, Pawson, T, McDonnell, D, Treuter, E, Gustafsson, J.A, Pike, A.C.W.
登録日2007-01-29
公開日2007-02-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Insights Into Corepressor Recognition by Antagonist-Bound Estrogen Receptors.
J.Biol.Chem., 282, 2007
2K31
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Solution Structure of cGMP-binding GAF domain of Phosphodiesterase 5
分子名称: GUANOSINE-3',5'-MONOPHOSPHATE, Phosphodiesterase 5A, cGMP-specific
著者Heikaus, C.C, Stout, J.R, Sekharan, M.R, Eakin, C.M, Rajagopal, P, Brzovic, P.S, Beavo, J.A, Klevit, R.E.
登録日2008-04-16
公開日2008-06-03
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution Structure of the cGMP Binding GAF Domain from Phosphodiesterase 5: Insights into Nucleotide Selectivity, Dimerization, and cGMP-Dependent Conformational Change.
J.Biol.Chem., 283, 2008
2JX1
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Structure of the fifth zinc finger of Myelin Transcription Factor 1 in complex with RARE DNA
分子名称: DNA (5'-D(*DAP*DCP*DCP*DGP*DAP*DAP*DAP*DGP*DTP*DTP*DCP*DAP*DC)-3'), DNA (5'-D(*DGP*DTP*DGP*DAP*DAP*DCP*DTP*DTP*DTP*DCP*DGP*DGP*DT)-3'), Myelin transcription factor 1
著者Gamsjaeger, R, Swanton, M.K, Kobus, F.J, Lehtomaki, E, Lowry, J.A, Kwan, A.H, Matthews, J.M, Mackay, J.P.
登録日2007-11-01
公開日2007-12-11
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the fifth zinc finger of Myelin Transcription Factor 1 in complex with RARE DNA
To be Published
2JK7
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XIAP BIR3 bound to a Smac Mimetic
分子名称: (3S,6S,7Z,10AS)-N-(DIPHENYLMETHYL)-6-{[(2S)-2-(METHYLIDENEAMINO)BUTANOYL]AMINO}-5-OXO-1,2,3,5,6,9,10,10A-OCTAHYDROPYRROLO[1,2-A]AZOCINE-3-CARBOXAMIDE, BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4, ZINC ION
著者Saito, N.G, Meagher, J.L, Stuckey, J.A.
登録日2008-08-21
公開日2008-11-04
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Structure-Based Design, Synthesis, Evaluation, and Crystallographic Studies of Conformationally Constrained Smac Mimetics as Inhibitors of the X-Linked Inhibitor of Apoptosis Protein (Xiap).
J.Med.Chem., 51, 2008
2JVJ
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NMR Solution Structure of the Hyper-Sporulation Response Regulator Spo0F Mutant I90A from Bacillus subtilis
分子名称: Sporulation initiation phosphotransferase F
著者Bobay, B.G, McLaughlin, P.D, Thompson, R.J, Hoch, J.A, Cavanagh, J.
登録日2007-09-20
公開日2008-02-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Covariance identifies dynamic residues at the interfaces in protein/protein complexes
To be Published
2KZZ
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KLENOW FRAGMENT WITH NORMAL SUBSTRATE AND ZINC ONLY
分子名称: DNA (5'-D(*GP*CP*TP*T*AP*CP*G)-3'), PROTEIN (DNA POLYMERASE I), ZINC ION
著者Brautigam, C.A, Sun, S, Piccirilli, J.A, Steitz, T.A.
登録日1998-07-07
公開日1999-12-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli.
Biochemistry, 38, 1999

223790

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