1ROT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rot by Molmil](/molmil-images/mine/1rot) | STRUCTURE OF FKBP59-I, THE N-TERMINAL DOMAIN OF A 59 KDA FK506-BINDING PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | FKBP59-I | Authors: | Craescu, C.T, Rouviere, N, Popescu, A, Cerpolini, E, Lebeau, M.-C, Baulieu, E.-E, Mispelter, J. | Deposit date: | 1996-06-14 | Release date: | 1996-12-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Three-dimensional structure of the immunophilin-like domain of FKBP59 in solution. Biochemistry, 35, 1996
|
|
7L8R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7l8r by Molmil](/molmil-images/mine/7l8r) | Crystal structure of human GPX4-U46C mutant K48A | Descriptor: | Isoform Cytoplasmic of Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION | Authors: | Forouhar, F, Liu, H, Seibt, T, Saneto, R, Wigby, K, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R. | Deposit date: | 2020-12-31 | Release date: | 2021-12-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism Nat.Chem.Biol., 2021
|
|
2ZQT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zqt by Molmil](/molmil-images/mine/2zqt) | |
5BNW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5bnw by Molmil](/molmil-images/mine/5bnw) | The active site of O-GlcNAc transferase imposes constraints on substrate sequence | Descriptor: | (2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, laminB1 residues 179-191 | Authors: | Pathak, S, Alonso, J, Schimpl, M, Rafie, K, Blair, D.E, Borodkin, V.S, Albarbarawi, O, van Aalten, D.M.F. | Deposit date: | 2015-05-26 | Release date: | 2015-08-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The active site of O-GlcNAc transferase imposes constraints on substrate sequence. Nat.Struct.Mol.Biol., 22, 2015
|
|
5AXK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5axk by Molmil](/molmil-images/mine/5axk) | Crystal structure of Thg1 like protein (TLP) | Descriptor: | GLYCEROL, tRNA(His)-5'-guanylyltransferase (Thg1) like protein | Authors: | Kimura, S, Suzuki, T, Yu, J, Kato, K, Yao, M. | Deposit date: | 2015-07-31 | Release date: | 2016-08-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Template-dependent nucleotide addition in the reverse (3'-5') direction by Thg1-like protein Sci Adv, 2, 2016
|
|
7L8L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7l8l by Molmil](/molmil-images/mine/7l8l) | Crystal structure of human R152H GPX4-U46C | Descriptor: | Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION | Authors: | Forouhar, F, Liu, H, Seibt, T, Saneto, R, Wigby, K, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R. | Deposit date: | 2020-12-31 | Release date: | 2021-12-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism Nat.Chem.Biol., 2021
|
|
3KUZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3kuz by Molmil](/molmil-images/mine/3kuz) | Crystal structure of the ubiquitin like domain of PLXNC1 | Descriptor: | Plexin-C1, UNKNOWN ATOM OR ION | Authors: | Wang, H, Li, B, Tempel, W, Tong, Y, Guan, X, Zhong, N, Crombet, L, MacKenzie, F, Buck, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-11-28 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the ubiquitin like domain of PLXNC1 to be published
|
|
8K4Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k4y by Molmil](/molmil-images/mine/8k4y) | Structure of a triple-helix region of human ReCol 3 from Trautec | Descriptor: | SULFATE ION, triple-helix region of human ReCol 3 | Authors: | Chu, Y, Zhai, Y, Fan, X, Li, J, Wang, L, Fu, S, Feng, P, Qian, S. | Deposit date: | 2023-07-20 | Release date: | 2023-08-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of a triple-helix region of human ReCol 3 from Trautec. To Be Published
|
|
1H4D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1h4d by Molmil](/molmil-images/mine/1h4d) | Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis protein MobA | Descriptor: | CITRIC ACID, LITHIUM ION, MOLYBDOPTERIN-GUANINE DINUCLEOTIDE BIOSYNTHESIS PROTEIN A | Authors: | Guse, A, Stevenson, C.E.M, Kuper, J, Buchanan, G, Schwarz, G, Mendel, R.R, Lawson, D.M, Palmer, T. | Deposit date: | 2003-02-26 | Release date: | 2003-05-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Biochemical and Structural Analysis of the Molybdenum Cofactor Biosynthesis Protein Moba J.Biol.Chem., 278, 2003
|
|
7L8M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7l8m by Molmil](/molmil-images/mine/7l8m) | Crystal structure of human GPX4-U46C mutant K48L | Descriptor: | Phospholipid hydroperoxide glutathione peroxidase | Authors: | Forouhar, F, Liu, H, Seibt, T, Saneto, R, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R. | Deposit date: | 2020-12-31 | Release date: | 2021-12-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism Nat.Chem.Biol., 2021
|
|
8K4X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k4x by Molmil](/molmil-images/mine/8k4x) | Structure of a triple-helix region of human Collagen type XVII from Trautec | Descriptor: | triple-helix region of human Collagen type XVII | Authors: | Chu, Y, Zhai, Y, Fan, X, Li, J, Wang, L, Fu, S, Feng, P, Qian, S. | Deposit date: | 2023-07-20 | Release date: | 2023-08-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of a triple-helix region of human Collagen type XVII from Trautec. To Be Published
|
|
1H8Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1h8z by Molmil](/molmil-images/mine/1h8z) | Crystal structure of the class D beta-lactamase OXA-13 | Descriptor: | BETA-LACTAMASE, SULFATE ION | Authors: | Pernot, L, Frenois, F, Rybkine, T, L'Hermite, G, Petrella, S, Delettre, J, Jarlier, V, Collatz, E, Sougakoff, W. | Deposit date: | 2001-02-17 | Release date: | 2001-07-12 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structures of the Class D B-Lactamase Oxa-13 in the Native Form and in Complex with Meropenem J.Mol.Biol., 310, 2001
|
|
2ZJG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zjg by Molmil](/molmil-images/mine/2zjg) | Crystal structural of mouse kynurenine aminotransferase III | Descriptor: | GLYCEROL, Kynurenine-oxoglutarate transaminase 3 | Authors: | Han, Q, Cai, T, Tagle, D.A, Robinson, H, Li, J. | Deposit date: | 2008-03-07 | Release date: | 2009-01-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural and functional characterization of mouse kynurenine aminotransferase III To be Published
|
|
5BPZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5bpz by Molmil](/molmil-images/mine/5bpz) | Atomic-resolution structures of the APC/C subunits Apc4 and the Apc5 N-terminal domain | Descriptor: | 1,2-ETHANEDIOL, Anapc5 protein | Authors: | Cronin, N, Yang, J, Zhang, Z, Barford, D. | Deposit date: | 2015-05-28 | Release date: | 2015-09-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Atomic-Resolution Structures of the APC/C Subunits Apc4 and the Apc5 N-Terminal Domain. J.Mol.Biol., 427, 2015
|
|
2ZUA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zua by Molmil](/molmil-images/mine/2zua) | Crystal structure of nucleoside diphosphate kinase from Haloarcula quadrata | Descriptor: | Nucleoside diphosphate kinase | Authors: | Ichimura, T, Yamamura, A, Ohtsuka, J, Miyazono, K, Okai, M, Nagata, K, Tanokura, M. | Deposit date: | 2008-10-15 | Release date: | 2009-08-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Molecular mechanism of distinct salt-dependent enzyme activity of two halophilic nucleoside diphosphate kinases Biophys.J., 96, 2009
|
|
7LA4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7la4 by Molmil](/molmil-images/mine/7la4) | Integrin AlphaIIbBeta3-PT25-2 Complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Bush, M.W, Walz, T, Coller, B, Filizola, M, Spasic, A, Nesic, D, Li, J. | Deposit date: | 2021-01-05 | Release date: | 2022-01-12 | Last modified: | 2022-07-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Electron microscopy shows that binding of monoclonal antibody PT25-2 primes integrin alpha IIb beta 3 for ligand binding. Blood Adv, 5, 2021
|
|
1ROU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rou by Molmil](/molmil-images/mine/1rou) | STRUCTURE OF FKBP59-I, THE N-TERMINAL DOMAIN OF A 59 KDA FK506-BINDING PROTEIN, NMR, 22 STRUCTURES | Descriptor: | FKBP59-I | Authors: | Craescu, C.T, Rouviere, N, Popescu, A, Cerpolini, E, Lebeau, M.-C, Baulieu, E.-E, Mispelter, J. | Deposit date: | 1996-06-14 | Release date: | 1996-12-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Three-dimensional structure of the immunophilin-like domain of FKBP59 in solution. Biochemistry, 35, 1996
|
|
5KGL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5kgl by Molmil](/molmil-images/mine/5kgl) | 2.45A resolution structure of Apo independent phosphoglycerate mutase from C. elegans (orthorhombic form) | Descriptor: | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, CHLORIDE ION, MANGANESE (II) ION, ... | Authors: | Lovell, S, Mehzabeen, N, Battaile, K.P, Yu, H, Dranchak, P, MacArthur, R, Li, Z, Carlow, T, Suga, H, Inglese, J. | Deposit date: | 2016-06-13 | Release date: | 2017-04-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases. Nat Commun, 8, 2017
|
|
8K4W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8k4w by Molmil](/molmil-images/mine/8k4w) | Structure of a triple-helix region of human collagen type I from Trautec | Descriptor: | CHLORIDE ION, triple-helix region of human collagen type I | Authors: | Chu, Y, Zhai, Y, Fan, X, Li, J, Wang, L, Fu, S, Feng, P, Qian, S. | Deposit date: | 2023-07-20 | Release date: | 2023-08-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of a triple-helix region of human collagen type I from Trautec. To Be Published
|
|
1OZE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1oze by Molmil](/molmil-images/mine/1oze) | Crystal Structures of the Ferric, Ferrous, and Ferrous-NO Forms of the Asp140Ala Mutant of Human Heme Oxygenase-1:Catalytic Implications | Descriptor: | Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Lad, L, Wang, J, Li, H, Friedman, J, Ortiz de Montellano, P.R, Poulos, T.L. | Deposit date: | 2003-04-08 | Release date: | 2003-08-05 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Crystal structures of the ferric, ferrous, and ferrous-NO forms of the Asp140Ala mutant of human heme oxygenase-1: catalytic implications J.Mol.Biol., 330, 2003
|
|
7LUM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lum by Molmil](/molmil-images/mine/7lum) | Human TRiC in ATP/AlFx closed state | Descriptor: | T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ... | Authors: | Knowlton, J.J, Gestaut, D, Ma, B, Taylor, G, Seven, A.B, Leitner, A, Wilson, G.J, Shanker, S, Yates, N.A, Prasad, B.V.V, Aebersold, R, Chiu, W, Frydman, J, Dermody, T.S. | Deposit date: | 2021-02-22 | Release date: | 2021-03-03 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural and functional dissection of reovirus capsid folding and assembly by the prefoldin-TRiC/CCT chaperone network. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7LBE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lbe by Molmil](/molmil-images/mine/7lbe) | CryoEM structure of the HCMV Trimer gHgLgO in complex with neutralizing fabs 13H11 and MSL-109 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, ... | Authors: | Kschonsak, M, Rouge, L, Arthur, C.P, Hoangdung, H, Patel, N, Kim, I, Johnson, M, Kraft, E, Rohou, A.L, Gill, A, Martinez-Martin, N, Payandeh, J, Ciferri, C. | Deposit date: | 2021-01-07 | Release date: | 2021-03-10 | Last modified: | 2021-03-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structures of HCMV Trimer reveal the basis for receptor recognition and cell entry. Cell, 184, 2021
|
|
5B1B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5b1b by Molmil](/molmil-images/mine/5b1b) | Bovine heart cytochrome c oxidase in the fully reduced state at 1.6 angstrom resolution | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | Authors: | Yano, N, Muramoto, K, Shimada, A, Takemura, S, Baba, J, Fujisawa, H, Mochizuki, M, Shinzawa-Itoh, K, Yamashita, E, Tsukihara, T, Yoshikawa, S. | Deposit date: | 2015-12-01 | Release date: | 2016-09-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The Mg2+-containing Water Cluster of Mammalian Cytochrome c Oxidase Collects Four Pumping Proton Equivalents in Each Catalytic Cycle. J.Biol.Chem., 291, 2016
|
|
7LMT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lmt by Molmil](/molmil-images/mine/7lmt) | Histone-lysine N-methyltransferase NSD2-PWWP1 with compound MRT10241866a | Descriptor: | Histone-lysine N-methyltransferase NSD2, UNKNOWN ATOM OR ION, ~{N}-cyclopropyl-3-oxidanylidene-~{N}-(thiophen-2-ylmethyl)-4~{H}-1,4-benzoxazine-7-carboxamide | Authors: | Lei, M, Freitas, R.F, Dong, A, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2021-02-05 | Release date: | 2021-03-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Histone-lysine N-methyltransferase NSD2-PWWP1 with compound MRT10241866a To Be Published
|
|
1OSN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1osn by Molmil](/molmil-images/mine/1osn) | Crystal structure of Varicella zoster virus thymidine kinase in complex with BVDU-MP and ADP | Descriptor: | (E)-5-(2-BROMOVINYL)-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Thymidine kinase | Authors: | Bird, L.E, Ren, J, Wright, A, Leslie, K.D, Degreve, B, Balzarini, J, Stammers, D.K. | Deposit date: | 2003-03-20 | Release date: | 2003-06-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of varicella zoster virus thymidine kinase J.Biol.Chem., 278, 2003
|
|