7LBE

CryoEM structure of the HCMV Trimer gHgLgO in complex with neutralizing fabs 13H11 and MSL-109

Summary for 7LBE

• Entry DOI: 10.2210/pdb7lbe/pdb
• EMDB information: 23252
• Descriptor: Envelope glycoprotein H, 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose, ... (11 entities in total)
• Functional Keywords: virus, receptor, complex, neutralizing antibody, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Human cytomegalovirus (strain Merlin) (HHV-5); More
• Total number of polymer chains: 7
• Total formula weight: 290381.25

Authors

Kschonsak, M.,Rouge, L.,Arthur, C.P.,Hoangdung, H.,Patel, N.,Kim, I.,Johnson, M.,Kraft, E.,Rohou, A.L.,Gill, A.,Martinez-Martin, N.,Payandeh, J.,Ciferri, C. (deposition date: 2021-01-07, release date: 2021-03-10, Last modification date: 2021-03-17)

• Primary citation: Kschonsak, M.,Rouge, L.,Arthur, C.P.,Hoangdung, H.,Patel, N.,Kim, I.,Johnson, M.C.,Kraft, E.,Rohou, A.L.,Gill, A.,Martinez-Martin, N.,Payandeh, J.,Ciferri, C.; Structures of HCMV Trimer reveal the basis for receptor recognition and cell entry.; Cell, 184:1232-, 2021; PubMed: 33626330; DOI: 10.1016/j.cell.2021.01.036

Experimental method

ELECTRON MICROSCOPY (2.9 Å)