5KGL

2.45A resolution structure of Apo independent phosphoglycerate mutase from C. elegans (orthorhombic form)

Summary for 5KGL

Entry DOI	10.2210/pdb5kgl/pdb
Related	5KGM 5KGN
Descriptor	2,3-bisphosphoglycerate-independent phosphoglycerate mutase, CHLORIDE ION, MANGANESE (II) ION, ... (6 entities in total)
Functional Keywords	metal binding, coupled enzyme assay, hts, structure activity relationship, rapid systems, high throughput enzymology, isomerase
Biological source	Caenorhabditis elegans
Total number of polymer chains	2
Total formula weight	122630.04
Authors	Lovell, S.,Mehzabeen, N.,Battaile, K.P.,Yu, H.,Dranchak, P.,MacArthur, R.,Li, Z.,Carlow, T.,Suga, H.,Inglese, J. (deposition date: 2016-06-13, release date: 2017-04-05, Last modification date: 2023-09-27)
Primary citation	Yu, H.,Dranchak, P.,Li, Z.,MacArthur, R.,Munson, M.S.,Mehzabeen, N.,Baird, N.J.,Battalie, K.P.,Ross, D.,Lovell, S.,Carlow, C.K.,Suga, H.,Inglese, J. Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases. Nat Commun, 8:14932-14932, 2017 Cited by PubMed: 28368002 DOI: 10.1038/ncomms14932 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45 Å)

Structure validation