6NAF
| De novo designed homo-trimeric amantadine-binding protein | 分子名称: | (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, SODIUM ION, amantadine-binding protein | 著者 | Selvaraj, B, Park, J, Cuneo, M.J, Myles, D.A.A, Baker, D. | 登録日 | 2018-12-05 | 公開日 | 2019-12-18 | 最終更新日 | 2023-10-25 | 実験手法 | NEUTRON DIFFRACTION (1.923 Å), X-RAY DIFFRACTION | 主引用文献 | De novo design of a homo-trimeric amantadine-binding protein. Elife, 8, 2019
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2XVD
| ephB4 kinase domain inhibitor complex | 分子名称: | EPHRIN TYPE-B RECEPTOR 4, MAGNESIUM ION, {4-METHYL-3-[(1-METHYLETHYL)(2-{[3-(METHYLSULFONYL)-5-MORPHOLIN-4-YLPHENYL]AMINO}PYRIMIDIN-4-YL)AMINO]PHENYL}METHANOL | 著者 | Read, J, Brassington, C.A, Green, I, McCall, E.J, Valentine, A.L. | 登録日 | 2010-10-25 | 公開日 | 2011-06-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Inhibitors of the Tyrosine Kinase Ephb4. Part 4: Discovery and Optimization of a Benzylic Alcohol Series. Bioorg.Med.Chem.Lett., 21, 2011
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2XYR
| Crystal structure of the nsp16 nsp10 SARS coronavirus complex | 分子名称: | CHLORIDE ION, MAGNESIUM ION, NON-STRUCTURAL PROTEIN 10, ... | 著者 | Decroly, E, Debarnot, C, Ferron, F, Bouvet, M, Coutard, B, Imbert, I, Gluais, L, Papageorgiou, N, Ortiz-Lombardia, M, Lescar, J, Canard, B. | 登録日 | 2010-11-18 | 公開日 | 2011-10-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex. Plos Pathog., 7, 2011
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2XWA
| Crystal Structure of Complement Factor D Mutant R202A | 分子名称: | COMPLEMENT FACTOR D, GLYCEROL | 著者 | Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P. | 登録日 | 2010-11-01 | 公開日 | 2011-01-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation. Science, 330, 2010
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2XZ4
| Crystal structure of the LFZ ectodomain of the peptidoglycan recognition protein LF | 分子名称: | 1,2-ETHANEDIOL, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, COPPER (II) ION, ... | 著者 | Basbous, N, Coste, F, Leone, P, Vincentelli, R, Royet, J, Kellenberger, C, Roussel, A. | 登録日 | 2010-11-23 | 公開日 | 2011-04-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | The Drosophila Peptidoglycan-Recognition Protein Lf Interacts with Peptidoglycan-Recognition Protein Lc to Downregulate the Imd Pathway. Embo Rep., 12, 2011
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2XZZ
| Crystal structure of the human transglutaminase 1 beta-barrel domain | 分子名称: | PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE K | 著者 | Vollmar, M, Krysztofinska, E, Krojer, T, Yue, W.W, Cooper, C, Kavanagh, K, Allerston, C, Chaikuad, A, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U. | 登録日 | 2010-11-30 | 公開日 | 2011-01-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of the Human Transglutaminase 1 Beta-Barrel Domain To be Published
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2Y1T
| Bacillus subtilis prophage dUTPase in complex with dUDP | 分子名称: | DEOXYURIDINE-5'-DIPHOSPHATE, SPBC2 PROPHAGE-DERIVED DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YOSS | 著者 | Garcia-Nafria, J, Harkiolaki, M, Persson, R, Fogg, M.J, Wilson, K.S. | 登録日 | 2010-12-10 | 公開日 | 2011-02-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | The Structure of Bacillus Subtilis Sp Beta Prophage Dutpase and its Complexes with Two Nucleotides Acta Crystallogr.,Sect.D, 67, 2011
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214D
| THE SOLUTION STRUCTURE OF A DNA DUPLEX CONTAINING A SINGLE 2'-O-METHYL-BETA-D-ARAT | 分子名称: | DNA (5'-D(*CP*GP*CP*AP*TP*AP*TP*AP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*AP*(T41)P*AP*TP*GP*CP*G)-3') | 著者 | Gotfredsen, C.H, Spielmann, H.P, Wengel, J, Jacobsen, J.P. | 登録日 | 1995-07-07 | 公開日 | 1995-10-15 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of a DNA duplex containing a single 2'-O-methyl-beta-D-araT: combined use of NMR, restrained molecular dynamics, and full relaxation matrix refinement. Bioconjug.Chem., 7, 1996
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6NT3
| Cryo-EM structure of a human-cockroach hybrid Nav channel. | 分子名称: | (7E,21R,24S)-27-amino-24-hydroxy-18,24-dioxo-19,23,25-trioxa-24lambda~5~-phosphaheptacos-7-en-21-yl (9Z,12E)-octadeca-9,12-dienoate, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Clairfeuille, T, Rohou, A, Payandeh, J. | 登録日 | 2019-01-28 | 公開日 | 2019-02-20 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structures of a human-cockroach hybrid Nav channel in the presence and absence of the alpha-scorpion toxin AaH2. Science, 2019
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4KYZ
| Three-dimensional structure of triclinic form of de novo design insertion domain, Northeast Structural Genomics Consortium (NESG) Target OR327 | 分子名称: | Designed protein OR327 | 著者 | Kuzin, A, Su, M, Seetharaman, J, Maglaqui, M, Xiao, R, Lee, D, Gleixner, J, Baker, D, Everett, J.K, Acton, T.B, Kornhaber, G, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-05-29 | 公開日 | 2013-07-24 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.492 Å) | 主引用文献 | Precise assembly of complex beta sheet topologies from de novo designed building blocks. Elife, 4, 2015
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2AF8
| ACTINORHODIN POLYKETIDE SYNTHASE ACYL CARRIER PROTEIN FROM STREPTOMYCES COELICOLOR A3(2), NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | ACTINORHODIN POLYKETIDE SYNTHASE ACYL CARRIER PROTEIN | 著者 | Crump, M.P, Crosby, J, Dempsey, C.E, Parkinson, J.A, Murray, M, Hopwood, D.A, Simpson, T.J. | 登録日 | 1997-03-23 | 公開日 | 1997-09-26 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2). Biochemistry, 36, 1997
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2AKZ
| Fluoride Inhibition of Enolase: Crystal Structure of the Inhibitory Complex | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FLUORIDE ION, Gamma enolase, ... | 著者 | Qin, J, Chai, G, Brewer, J.M, Lovelace, L.L. | 登録日 | 2005-08-04 | 公開日 | 2006-03-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Fluoride inhibition of enolase: crystal structure and thermodynamics Biochemistry, 45, 2006
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1MX8
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2ANB
| Crystal Structure Of Oligomeric E.coli Guanylate Kinase In Complex With GMP | 分子名称: | GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase, SULFATE ION | 著者 | Hible, G, Renault, L, Schaeffer, F, Christova, P, Radulescu, A.Z, Evrin, C, Gilles, A.M, Cherfils, J. | 登録日 | 2005-08-11 | 公開日 | 2005-08-30 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Calorimetric and crystallographic analysis of the oligomeric structure of Escherichia coli GMP kinase J.Mol.Biol., 352, 2005
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1JBI
| NMR structure of the LCCL domain | 分子名称: | cochlin | 著者 | Liepinsh, E, Trexler, M, Kaikkonen, A, Weigelt, J, Banyai, L, Patthy, L, Otting, G. | 登録日 | 2001-06-05 | 公開日 | 2001-10-17 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of the LCCL domain and implications for DFNA9 deafness disorder. EMBO J., 20, 2001
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6NXJ
| Flavin Transferase ApbE from Vibrio cholerae, H257G mutant | 分子名称: | FAD:protein FMN transferase, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION | 著者 | Osipiuk, J, Fang, X, Chakravarthy, S, Juarez, O, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-02-08 | 公開日 | 2019-03-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Conserved residue His-257 ofVibrio choleraeflavin transferase ApbE plays a critical role in substrate binding and catalysis. J.Biol.Chem., 294, 2019
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4L2I
| Electron transferring flavoprotein of Acidaminococcus fermentans: Towards a mechanism of flavin-based electron bifurcation | 分子名称: | CHLORIDE ION, Electron transfer flavoprotein alpha subunit, Electron transfer flavoprotein alpha/beta-subunit, ... | 著者 | Mowafy, A.M, Chowdhury, N.P, Demmer, J, Upadhyay, V, Kolzer, S, Jayamani, E, Kahnt, J, Demmer, U, Ermler, U, Buckel, W. | 登録日 | 2013-06-04 | 公開日 | 2014-01-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Studies on the Mechanism of Electron Bifurcation Catalyzed by Electron Transferring Flavoprotein (Etf) and Butyryl-CoA Dehydrogenase (Bcd) of Acidaminococcus fermentans. J.Biol.Chem., 289, 2014
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6NO4
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5TBD
| Crystal Structure of anti-MSP2 Fv fragment (mAb4D11) in complex with 3D7-MSP2 215-222 | 分子名称: | Fv fragment (mAb4D1) heavy chain, Merozoite surface protein 2 | 著者 | Seow, J, Morales, R.A.V, MacRaild, C.A, Bankala, K, Drinkwater, N, Dingjan, T, Jaipuria, G, Wilde, K, Anders, R.F, Atreya, H.S, Christ, D, McGowan, S, Norton, R.S. | 登録日 | 2016-09-12 | 公開日 | 2017-02-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure and Characterisation of a Key Epitope in the Conserved C-Terminal Domain of the Malaria Vaccine Candidate MSP2. J. Mol. Biol., 429, 2017
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5TBS
| Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase complexed with adenine | 分子名称: | ADENINE, DIMETHYL SULFOXIDE, Purine nucleoside phosphorylase | 著者 | Faheem, M, Torini, J.R, Romanello, L, Brandao-Neto, J, Pereira, H.M. | 登録日 | 2016-09-13 | 公開日 | 2017-10-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleoside selectivity of PNPs. PLoS ONE, 13, 2018
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2AKE
| Structure of human tryptophanyl-tRNA synthetase in complex with tRNA(Trp) | 分子名称: | SULFATE ION, TRYPTOPHAN, Tryptophanyl-tRNA synthetase, ... | 著者 | Shen, N, Guo, L, Yang, B, Jin, Y, Ding, J. | 登録日 | 2005-08-03 | 公開日 | 2006-07-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of human tryptophanyl-tRNA synthetase in complex with tRNA(Trp) reveals the molecular basis of tRNA recognition and specificity Nucleic Acids Res., 34, 2006
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2ANJ
| Crystal Structure of the Glur2 Ligand Binding Core (S1S2J-Y450W) Mutant in Complex With the Partial Agonist Kainic Acid at 2.1 A Resolution | 分子名称: | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2 | 著者 | Holm, M.M, Naur, P, Vestergaard, B, Geballe, M.T, Gajhede, M, Kastrup, J.S, Traynelis, S.F, Egebjerg, J. | 登録日 | 2005-08-11 | 公開日 | 2005-08-30 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A Binding Site Tyrosine Shapes Desensitization Kinetics and Agonist Potency at GluR2: a mutagenic, kinetic, and crystallographic study J.Biol.Chem., 280, 2005
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2AWG
| Structure of the PPIase domain of the Human FK506-binding protein 8 | 分子名称: | 38 kDa FK-506 binding protein | 著者 | Walker, J.R, Davis, T, Newman, E.M, Finerty, P, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2005-09-01 | 公開日 | 2005-09-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of the human FK-506 binding protein 8 To be Published
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2AOA
| Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain | 分子名称: | 2-(4-((9S,10S,14S,Z)-18-(2-AMINO-2-OXOETHYL)-9-(CARBOXYMETHYL)-14-(NAPHTHALEN-1-YLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL)PHENYL)MALONIC ACID, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Growth factor receptor-bound protein 2 | 著者 | Phan, J, Shi, Z.D, Burke, T.R, Waugh, D.S. | 登録日 | 2005-08-12 | 公開日 | 2005-10-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2 Domain. J.Mol.Biol., 353, 2005
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2AWN
| Crystal structure of the ADP-Mg-bound E. Coli MALK (Crystallized with ATP-Mg) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Maltose/maltodextrin import ATP-binding protein malK | 著者 | Lu, G, Westbrooks, J.M, Davidson, A.L, Chen, J. | 登録日 | 2005-09-01 | 公開日 | 2005-12-13 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | ATP hydrolysis is required to reset the ATP-binding cassette dimer into the resting-state conformation. Proc.Natl.Acad.Sci.Usa, 102, 2005
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