2AWG

Structure of the PPIase domain of the Human FK506-binding protein 8

Summary for 2AWG

• Entry DOI: 10.2210/pdb2awg/pdb
• Descriptor: 38 kDa FK-506 binding protein (2 entities in total)
• Functional Keywords: fkbp-type, ppiase, bcl-2 inhibitor, shh signalling antagonist, structural genomics consortium, sgc, signaling protein inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion membrane; Single-pass membrane protein; Cytoplasmic side (By similarity): Q14318
• Total number of polymer chains: 1
• Total formula weight: 12638.40

Authors

Walker, J.R.,Davis, T.,Newman, E.M.,Finerty, P.,Mackenzie, F.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2005-09-01, release date: 2005-09-27, Last modification date: 2023-08-23)

• Primary citation: Walker, J.R.,Davis, T.,Newman, E.M.,Finerty, P.,Mackenzie, F.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Bochkarev, A.,Dhe-Paganon, S.; Structure of the human FK-506 binding protein 8; To be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)